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Autor:
F. Kremer
Publikováno v:
Zeitschrift für Naturforschung C. 39:1204-1204
Autor:
E B Goosenberg, James M. Gallo, P F Engstrom, Thomas C. Hamilton, Christine E. Szarka, T Halbherr, A M Balshem, G R Pfeiffer, F Green, Kang Shen Yao, M L Clapper, Peter J. O'Dwyer, H Frucht, Samuel Litwin, James M. Brennan
Publikováno v:
Journal of Clinical Investigation. 98:1210-1217
Prolonged exposure to mutagenic substances is strongly associated with an individual's risk of developing colorectal cancer. Clinical investigation of oltipraz as a chemopreventive agent is supported by its induction of the expression of detoxication
Autor:
N. Y. Jiang, Jacques-Pierre Moreau, Jia-Ming Qian, Sun Hyuk Kim, H. Frucht, David H. Coy, R. T. Jensen, Lu-Wa Wang, Jaw-Town Lin
Publikováno v:
Journal of Biological Chemistry. 266:16441-16447
During a search for possible cyclization points in shortened, potent bombesin agonists and antagonists, it was found that the joining of amino acid residues in positions 6 and 14 by various means resulted in retention of significant binding affinity
Publikováno v:
Journal of Clinical Investigation. 86:1904-1912
Cholera toxin (CT) inhibited the in vitro growth of three of four human small-cell lung carcinoma (SCLC) cell lines with a 50% inhibitory concentration of 27-242 ng/ml. Loss of surface membrane ruffling and the capacity of [Tyr4]-bombesin, vasopressi
Autor:
C E, Szarka, K S, Yao, G R, Pfeiffer, A M, Balshem, S, Litwin, H, Frucht, E B, Goosenberg, P F, Engstrom, M L, Clapper, P J, O'Dwyer
Publikováno v:
Cancer detection and prevention. 25(4)
The dithiolethione oltipraz is being developed as a chemopreventive agent for many malignancies, including colorectal cancer, on the basis of its in vivo protective activity against chemically induced tumors in a variety of animal models. This protec
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(9)
We have demonstrated previously cell surface receptors for gastrointestinal peptides on 10 human colon cancer cell lines. Because most of the cells studied bind muscarinic cholinergic agonists, we undertook the determination of the cholinergic recept
Publikováno v:
University Chemistry. 2024, Vol. 39 Issue 3, p231-238. 8p.
Autor:
M L, Clapper, C E, Szarka, G R, Pfeiffer, T A, Graham, A M, Balshem, S, Litwin, E B, Goosenberg, H, Frucht, P F, Engstrom
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(1)
Previous studies suggest that cruciferous vegetables may provide protection against carcinogen exposure by inducing detoxification enzymes. ICR(Ha) mice were gavaged with broccoli tablets (1 g/kg), and colon tissues were collected after treatment. Gl