Zobrazeno 1 - 9
of 9
pro vyhledávání: '"A. H. Boulares"'
Autor:
Augusto C. Ochoa, Liqin Zheng, L. Del Valle, Maria Dulfary Sanchez-Pino, Amir A. Al-Khami, Jone Garay, Samuel C. Okpechi, A. H. Boulares, Salome V. Ibba, Paulo C. Rodriguez, Dorota Wyczechowska, Mohamed A. Ghonim, Kusma Pyakurel
Background Increasing evidence has shown the close link between energy metabolism and the differentiation, function, and longevity of immune cells. Chronic inflammatory conditions such as parasitic infections and cancer trigger a metabolic reprogramm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6214e6c0a6feda2ea0a0394f62173b
https://europepmc.org/articles/PMC5578913/
https://europepmc.org/articles/PMC5578913/
Autor:
Amarjit S. Naura, A. H. Boulares, Arthur L. Haas, Youssef Errami, Virginia P. Ronchi, Mourad Zerfaoui, Mustapha Oumouna, Rahul Datta, Hogyoung Kim, J. Ju
Publikováno v:
Allergy. 66:853-861
Background: We recently showed that poly(ADP-ribose)polymerase-1 (PARP-1) may play a role in allergen (ovalbumin)-induced airway eosinophilia, potentially through a specific effect on IL-5 production. We also reported that while IL-5 replenishment pr
Autor:
Cynthia M. Simbulan-Rosenthal, Linda H. Malkas, A H Boulares, Jennifer Coll, Robert J. Hickey, Dean S. Rosenthal, Mark E. Smulson
Publikováno v:
Biochemistry. 37:9363-9370
Poly(ADP-ribose) polymerase (PARP) is a component of the multiprotein DNA replication complex (MRC, DNA synthesome) that catalyzes replication of viral DNA in vitro. PARP poly(ADP-ribosyl)ates 15 of the approximately 40 proteins of the MRC, including
Autor:
Youssef Errami, Amarjit S. Naura, Rahul Datta, Bashir M. Rezk, A. H. Boulares, Chetan P. Hans, Khalid Matrougui, Mustapha Oumouna, Mourad Zerfaoui
Publikováno v:
The European respiratory journal. 33(2)
Inducible nitric oxide synthase (iNOS) inhibition was recently shown to exert no effect on allergen challenge in human asthma, raising serious concerns about the role of the protein in the disease. The present study investigated the role of iNOS in o
Autor:
Mustapha Oumouna, Mourad Zerfaoui, Amarjit S. Naura, Dahui You, Stephania A. Cormier, A. H. Boulares, Chetan P. Hans
Summary Background Identifying therapeutic drugs that block the release or effects of T-helper type 2 (Th2) cytokines after allergen exposure is an important goal for the treatment of allergic inflammatory diseases including asthma. We recently showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61e1a9b16884eb2622388f668e350ed
https://europepmc.org/articles/PMC2740645/
https://europepmc.org/articles/PMC2740645/
Autor:
A. Sheidlin, K. Kawakami, A. Yasukawa, S. Moochhala, C. N. D'Alessandro-Gabazza, A. W. Cheever, K. R. Qazi, M. Toda, C. Hans, A. Eklund, T. Takagi, M. Inui, E. C. Gabazza, I. O. Rosas, H. Kim, T. R. Ramalingam, N. Yamamoto, S. Gabrielsson, J. Park, D. Tanno, D. Boveda Ruiz, J. Ju, T. Aoyagi, M. Kaku, N. Mukaida, Y. Kuninaka, Y. Hirakata, L. Shi, A. C. Ochoa, B. Dahlberg, B. R. Gochuico, P. Torregrosa Paredes, J. Morser, O. Taguchi, P. C. Rodriguez, H. Kunishima, P. Gil Bernabe, A. Y. Ramirez-Marmol, K. Narasaiah, J. Lu, S. K. Madala, M. Naito, C. A. Hales, S. W. S. Sio, S. Leu, T. A. Wynn, T. Kondo, A. S. Naura, A. Kimura, H. Zhao, M. Kitagawa, M. Zerfaoui, Y. Miyake, J. Grunewald, M. Bhatia, H. Boulares, Y. Ishida, M. S. Wilson
Publikováno v:
International Immunology. 22:iv118-iv119
Publikováno v:
The Journal of biological chemistry. 274(33)
An early transient burst of poly(ADP-ribosyl)ation of nuclear proteins was recently shown to be required for apoptosis to proceed in various cell lines (Simbulan-Rosenthal, C., Rosenthal, D., Iyer, S., Boulares, H., and Smulson, M. (1998) J. Biol. Ch
Publikováno v:
Molecular and cellular biochemistry. 193(1-2)
We have focused on the roles of PARP and poly(ADP-ribosyl)ation early in apoptosis, as well as during the early stages of differentiation-linked DNA replication. In both nuclear processes, a transient burst of PAR synthesis and PARP expression occurs
Publikováno v:
Cancer research. 58(20)
The antiangiogenic, tubulin-binding drug combretastatin A-4 exhibits a selective toxicity for proliferating endothelial cells in vitro and induces vascular shutdown in tumor models in vivo. The mechanism of combretastatin A-4 cytotoxicity has now bee