Zobrazeno 1 - 10
of 62
pro vyhledávání: '"A. H. Beesley"'
Autor:
Tina Carter, Maxine Crook, Ashleigh Murch, Alex H. Beesley, Nick de Klerk, Adrian Charles, Ursula R. Kees
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background NUT carcinoma (NC), previously known as NUT midline carcinoma, is a rare and very aggressive cancer that occurs in both children and adults. NC is largely chemoresistant, with an overall survival of less than 7 months. Because the
Externí odkaz:
https://doaj.org/article/ac8e20fd505c4ce596078feda2e43064
Autor:
Anja Stirnweiss, Hetal Dholaria, Joyce Oommen, Kathy Hardy, Gareth Jevon, Alex H. Beesley, Rishi S. Kotecha
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
An 8-year and 10-month-old boy presented following 2 weeks of abdominal pain, vomiting, constipation, and rectal pain. A diffuse lower-abdominal mass was felt upon palpation, with radiological findings confirming the presence of a large, multilobulat
Externí odkaz:
https://doaj.org/article/e195495a3f034367b0a85ebe1d940f0b
Autor:
Ursula R. Kees, Jette Ford, Amy L. Samuels, Denise Anderson, Martin J. Firth, Alex H. Beesley
Patients relapsing with T-cell acute lymphoblastic leukemia (T-ALL) face a dismal outcome. The aim of this study was to identify new markers of drug resistance and clinical response in T-ALL. We measured gene expression and drug sensitivity in 15 ped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a377a32eda6df9a0ded304a0b16393
https://doi.org/10.1158/0008-5472.c.6505596
https://doi.org/10.1158/0008-5472.c.6505596
Autor:
Adrian Charles, Ursula R. Kees, Ashleigh Murch, Nicholas de Klerk, Tina Carter, Maxine Crook, Alex H. Beesley
Publikováno v:
BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Background NUT carcinoma (NC), previously known as NUT midline carcinoma, is a rare and very aggressive cancer that occurs in both children and adults. NC is largely chemoresistant, with an overall survival of less than 7 months. Because the carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe7ba227e93102ecfecbffbb6c391e6
https://doi.org/10.1186/s12885-021-08432-0
https://doi.org/10.1186/s12885-021-08432-0
Autor:
Alex H. Beesley, Hetal Dholaria, Rishi S. Kotecha, Kathy Hardy, Gareth Jevon, Joyce Oommen, Anja Stirnweiss
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
An 8-year and 10-month-old boy presented following 2 weeks of abdominal pain, vomiting, constipation, and rectal pain. A diffuse lower-abdominal mass was felt upon palpation, with radiological findings confirming the presence of a large, multilobulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13dc5580e63ec1c5c40888b6423e1d9f
https://www.frontiersin.org/articles/10.3389/fonc.2021.590913/full
https://www.frontiersin.org/articles/10.3389/fonc.2021.590913/full
Autor:
Rishi S. Kotecha, Jette Ford, Alex H. Beesley, Denise Anderson, Catherine H. Cole, Ursula R. Kees
Publikováno v:
Haematologica, Vol 97, Iss 9 (2012)
Externí odkaz:
https://doaj.org/article/56df332ac530407f991a66530e6057aa
Autor:
Richard W Francis, Katherine Thompson-Wicking, Kim W Carter, Denise Anderson, Ursula R Kees, Alex H Beesley
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39987 (2012)
The hallmarks of many haematological malignancies and solid tumours are chromosomal translocations, which may lead to gene fusions. Recently, next-generation sequencing techniques at the transcriptome level (RNA-Seq) have been used to verify known an
Externí odkaz:
https://doaj.org/article/5a4ece483d374a75936bb06a1368bb61
Publikováno v:
Oncotarget. 8:112313-112329
NUT midline carcinoma (NMC) is a rare and aggressive cancer, with survival typically less than seven months, that can arise in people of any age. Genetically, NMC is defined by the chromosomal fusion of NUTM1 with a chromatin-binding partner, typical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8688251fdb7b307d66d33278adfed2e
https://doi.org/10.18632/oncotarget.22862
https://doi.org/10.18632/oncotarget.22862
Autor:
Amy L. Samuels, Rosemary Sutton, Richard B. Lock, Julia E. Wells, Babasaheb D. Yadav, Katerina Bendak, Alex H. Beesley, Ursula R. Kees, Nicola C. Venn, Denise Anderson, Catherine H. Cole, Glenn M. Marshall
Publikováno v:
Oncotarget
Relapse in pediatric T-cell acute lymphoblastic leukemia (T-ALL) remains a significant clinical problem and is thought to be associated with clonal selection during treatment. In this study we used an established pre-clinical model of induction thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b344e8263b0fa63fa1b63f6eaa178f6
https://doi.org/10.18632/oncotarget.11233
https://doi.org/10.18632/oncotarget.11233
Autor:
E. Ferrari, Meegan Howlett, Anja Stirnweiss, Raelene Endersby, Adrian Charles, Catherine H. Cole, Timothy W. Failes, Ursula R. Kees, Alex H. Beesley, Greg M. Arndt
Publikováno v:
British Journal of Cancer
Background: The NUT midline carcinoma (NMC) is a rare but fatal cancer for which systematic testing of therapy options has never been performed. Methods: On the basis of disease biology, we compared the efficacy of the CDK9 inhibitor flavopiridol (FP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fa80538abd5964102f4604522cc777
https://doi.org/10.1038/bjc.2014.54
https://doi.org/10.1038/bjc.2014.54