Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques

Autor: Sommer Holmes, Hui Li, Xiaoying Shen, Mitchell Martin, Ryan Tuck, Yue Chen, Elena E. Giorgi, Hélène Fradin Kirshner, Madison Berry, Elizabeth Van Italie, Sravani Venkatayogi, Joshua S. Martin Beem, Robert J. Edwards, Katayoun Mansouri, Ajay Singh, Cindy Kuykendall, Thaddeus Gurley, M. Anthony Moody, Nicole DeNayer, Todd Demarco, Thomas N. Denny, Yunfei Wang, Tyler D. Evangelous, John T. Clinton, Bhavna Hora, Kshitij Wagh, Michael S. Seaman, Kevin O. Saunders, Nicholas Solomotis, Johnathan Misamore, Mark G. Lewis, Kevin Wiehe, David C. Montefiori, George M. Shaw, Wilton B. Williams

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)

Abstract The details of the pediatric immune system that supports induction of antibodies capable of neutralizing geographically-diverse or heterologous HIV-1 is currently unclear. Here we explore the pediatric immune environment in neonatal macaque

Externí odkaz: https://doaj.org/article/8a02ed03cb6c4c07b1bf35351c55e38c

Contribution of malnutrition to infant and child deaths in Sub-Saharan Africa and South Asia

Autor: Khatia Munguambe, Quique Bassat, Mahbubur Rahman, Sibone Mocumbi, Cynthia G Whitney, Amy Wise, Shams El Arifeen, Meerjady Sabrina Flora, Soter Ameh, Emily S Gurley, Mustafizur Rahman, Ariel Nhacolo, Cheick Bougadari Traore, Inacio Mandomando, Clara Menendez, Janet Agaya, Jane Juma, Shabir A Madhi, Tadesse Gure, George Aol, Hennie Lombaard, Ziyaad Dangor, James Bunn, Samba O Sow, Amara Jambai, Dickson Gethi, Sanwarul Bari, Natalia Rakislova, Tacilta Nhampossa, Maria Maixenchs, Mohammed Kamal, Joseph Oundo, Lola Madrid, Tahmina Shirin, Ikechukwu Udo Ogbuanu, Addisu Alemu, Hailemariam Legesse, Awa Traore, Portia C Mutevedzi, Helina Heluf, Victor Akelo, Dickens Onyango, Richard Omore, Yasmin Adam, Peter Otieno, Margaret Mannah, Karen L Kotloff, Milagritos D Tapia, Rima Koka, Mohammad Zahid Hossain, Dickens Kowuor, Tom Sesay, James Squire, Francis Moses, Kitiezo Aggrey Igunza, Andrew Moseray, Afruna Rahman, Nana Kourouma, Seydou Sissoko, Rosauro Varo, Sana Mahtab, Martin Hale, Jeanie du Toit, Zachary J Madewell, Dianna M Blau, Fatima Solomon, Gillian Sorour, Jeannette Wadula, Karen Petersen, Sanjay G Lala, Sithembiso Velaphi, Richard Chawana, Nellie Myburgh, Shahana Parveen, Mahbubul Hoque, Saria Tasnim, Ferdousi Islam, Farida Ariuman, Mohammad Mosiur Rahman, Dilruba Ahmed, Fikremelekot Temesgen, Melisachew Mulatu Yeshi, Mahlet Abayneh Gizaw, Stian MS Orlien, Solomon Ali, Peter Nyamthimba Onyango, Richard Oliech, Joyce Akinyi Were, Thomas Misore, Harun Owuor, Christopher Muga, Christine Ochola, Ashka Mehta, Brigitte Gaume, Adama Mamby Keita, Diakaridia Kone, Diakaridia Sidibe, Doh Sanogo, Kounandji Diarra, Tiéman Diarra, Kiranpreet Chawla, Zara Manhique, Fatmata Bintu Tarawally, Martin Seppeh, Ronald Mash, Julius Ojulong, Babatunde Duduyemi, Alim Swaray-Deen, Okokon Ita, Cornell Chukwuegbo, Sulaiman Sannoh, Princewill Nwajiobi, Erick Kaluma, Oluseyi Balogun, Carrie Jo Cain, Solomon Samura, Samuel Pratt, Joseph Kamanda Sesay, Osman Kaykay, Binyam Halu, Francis Smart, Sartie Kenneh, Ferdousi Begum, Priya Mehta-Gupta Das, Ogony Benard Oluoch, Caleb K Sagam, Ronita Luke, Milton Kincardett, Elisio G Xerinda, Markus Roos Breines, Ketema Degefa, J. Anthony G Scott, Kazi Munisul Islam, Parminder S Suchdev, Nelesh P. Govender, Peter J. Swart, Nawshad Uddin Ahmed, Alexander M. Ibrahim, Sharon M. Tennant, Carol L. Greene, J. Kristie Johnson, Karen D. Fairchild, Uma U. Onwuchekwa, Joseph Bangura

Publikováno v: BMJ Global Health, Vol 9, Iss 12 (2024)

Introduction Malnutrition contributes to 45% of all childhood deaths globally, but these modelled estimates lack direct measurements in countries with high malnutrition and under-5 mortality rates. We investigated malnutrition’s role in infant and

Externí odkaz: https://doaj.org/article/080ae47446d94bdfba6536fa9e658e9e

Awareness, use, motivations and methods of accessing genetic testing in 2022 in the United States

Autor: Sukh Makhnoon, MinJae Lee, Tanushree Prasad, Alexa Badalamenti, Tami Gurley, Erika A. Waters, Celette Sugg Skinner

Publikováno v: Frontiers in Genetics, Vol 15 (2024)

IntroductionAwareness, access, and use of clinical and direct-to-consumer (DTC) genetic tests has increased in recent years with documented disparities in these services. We provide updated data on test awareness and use, and report novel data on mot

Externí odkaz: https://doaj.org/article/b5943c77edc84cbba62daf9dbf07842d

Management of isolated native tricuspid valve infective endocarditis by a multidisciplinary program: a single-center retrospective cohort study

Autor: Bennett Collis, Talal Alnabelsi, Evan Hall, Chloe Cao, Meredith Johnson, John Gurley, Luke Strnad, Hassan Reda, Tessa London, Erinn Ogburn, Michael Sekela, Bobbi Jo Stoner, Sami El-Dalati

Publikováno v: Therapeutic Advances in Infectious Disease, Vol 11 (2024)

Background: Isolated native tricuspid valve infective endocarditis remains a challenging disease to treat given the large number of patients with substance use disorder. There is limited data on the optimal treatment strategy and the impact of a mult

Externí odkaz: https://doaj.org/article/f88aef4053f04df0886a83683d9b1ea1

Etiologies and comorbidities of meningitis deaths in children under 5 years in high-mortality settings: Insights from the CHAMPS Network in the post-pneumococcal vaccine era

Autor: Mahtab, Sana ^{a, ⁎}, Madewell, Zachary J. ^b, Baillie, Vicky ^a, Dangor, Ziyaad ^a, Lala, Sanjay G. ^c, Assefa, Nega ^{d, e}, Berihun, Mulu ^d, Madrid, Lola ^{d, e}, Regassa, Lemma Demissie ^d, Scott, J. Anthony G. ^e, Ameh, Soter ^f, Bangura, Joseph S. ^g, Ita, Okokon ^h, Kaluma, Erick ^f, Ogbuanu, Ikechukwu Udo ^f, Gaume, Brigitte ⁱ, Kotloff, Karen L. ⁱ, Sow, Samba O. ^j, Tapia, Milagritos D. ⁱ, Ajanovic, Sara ^{k, l}, Garrine, Marcelino ^k, Mandomando, Inacio ^{k, l, m}, Varo, Rosauro ^{k, l}, Xerinda, Elisio G. ^k, Alam, Muntasir ⁿ, El Arifeen, Shams ⁿ, Gurley, Emily S. ^{n, o}, Hossain, Mohammad Zahid ⁿ, Rahman, Afruna ⁿ, Akelo, Victor ^p, Igunza, Kitiezo Aggrey ^q, Onyango, Clayton ^r, Onyango, Dickens ^s, Verani, Jennifer R. ^t, Mutevedzi, Portia ^u, Whitney, Cynthia G. ^u, Blau, Dianna M. ^b, Madhi, Shabir A. ^{a, v}, Bassat, Quique ^{k, l, w, x, y}

Publikováno v: In Journal of Infection December 2024 89(6)