Nivolumab and ipilimumab with concurrent stereotactic radiosurgery for intracranial metastases from non-small cell lung cancer: analysis of the safety cohort for non-randomized, open-label, phase I/II trial

Autor: Jing Li, Yan Wang, Chad Tang, James Welsh, Renata Ferrarotto, Mehmet Altan, Tina Cascone, Juhee Song, Marcelo V Negrao, John V Heymach, Brett W Carter, Ferdinandos Skoulidis, Yasir Y Elamin, Xiuning Le, Caroline Chung, George R Blumenschein, Nandita Guha-Thakurta, Jeffrey S Wefel, Amol J Ghia, Debra N Yeboa, Mary Frances McAleer, Kristina D Woodhouse, Susan L McGovern, Chenyang Wang, Betty Y S Kim, Jeffrey S Weinberg, Tina M Briere

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 7 (2023)

Background Up to 20% of patients with non-small cell lung cancer (NSCLC) develop brain metastasis (BM), for which the current standard of care is radiation therapy with or without surgery. There are no prospective data on the safety of stereotactic r

Externí odkaz: https://doaj.org/article/51e050d61d114362ab9f5637b2331ad5

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Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer

Autor: Francis, Alicia, Morgan, Allison M., Waanders, Angela J., Viaene, Angela N., Buccoliero, Anna Maria, Chinnaiyan, Arul M., Leonard, Carina A., Kline, Cassie N., Caporalini, Chiara, Kinsinger, Christopher R., Li, Chunde, Kram, David E., Hanson, Derek, Appert, Elizabeth, Kawaler, Emily A., Raabe, Eric H., Jackson, Eric M., Greenfield, Jeffrey P., Stone, Gabrielle S., Getz, Gad, Grant, Gerald, Teo, Guo Ci, Pollack, Ian F., Cain, Jason E., Foster, Jessica B., Phillips, Joanna J., Palma, July E., Ketchum, Karen A., Ruggles, Kelly V., Blumenberg, Lili, Cornwell, Macintosh, Sarmady, Mahdi, Domagalski, Marcin J., Cieślik, Marcin P., Santi, Mariarita, Li, Marilyn M., Ellis, Matthew J., Wyczalkowski, Matthew A., Connors, Meghan, Scagnet, Mirko, Gupta, Nalin, Edwards, Nathan J., Vitanza, Nicholas A., Vaske, Olena M., Becher, Oren, McGarvey, Peter B., Firestein, Ron, Mueller, Sabine, Winebrake, Samuel G., Dhanasekaran, Saravana Mohan, Cai, Shuang, Partap, Sonia, Patton, Tatiana, Le, Toan, Lorentzen, Travis D., Liu, Wenke, Bocik, William E., Petralia, Francesca, Tignor, Nicole, Reva, Boris, Koptyra, Mateusz, Chowdhury, Shrabanti, Rykunov, Dmitry, Krek, Azra, Ma, Weiping, Zhu, Yuankun, Ji, Jiayi, Calinawan, Anna, Whiteaker, Jeffrey R., Colaprico, Antonio, Stathias, Vasileios, Omelchenko, Tatiana, Song, Xiaoyu, Raman, Pichai, Guo, Yiran, Brown, Miguel A., Ivey, Richard G., Szpyt, John, Guha Thakurta, Sanjukta, Gritsenko, Marina A., Weitz, Karl K., Lopez, Gonzalo, Kalayci, Selim, Gümüş, Zeynep H., Yoo, Seungyeul, da Veiga Leprevost, Felipe, Chang, Hui-Yin, Krug, Karsten, Katsnelson, Lizabeth, Wang, Ying, Kennedy, Jacob J., Voytovich, Uliana J., Zhao, Lei, Gaonkar, Krutika S., Ennis, Brian M., Zhang, Bo, Baubet, Valerie, Tauhid, Lamiya, Lilly, Jena V., Mason, Jennifer L., Farrow, Bailey, Young, Nathan, Leary, Sarah, Moon, Jamie, Petyuk, Vladislav A., Nazarian, Javad, Adappa, Nithin D., Palmer, James N., Lober, Robert M., Rivero-Hinojosa, Samuel, Wang, Liang-Bo, Wang, Joshua M., Broberg, Matilda, Chu, Rosalie K., Moore, Ronald J., Monroe, Matthew E., Zhao, Rui, Smith, Richard D., Zhu, Jun, Robles, Ana I., Mesri, Mehdi, Boja, Emily, Hiltke, Tara, Rodriguez, Henry, Zhang, Bing, Schadt, Eric E., Mani, D.R., Ding, Li, Iavarone, Antonio, Wiznerowicz, Maciej, Schürer, Stephan, Chen, Xi S., Heath, Allison P., Rokita, Jo Lynne, Nesvizhskii, Alexey I., Fenyö, David, Rodland, Karin D., Liu, Tao, Gygi, Steven P., Paulovich, Amanda G., Resnick, Adam C., Storm, Phillip B., Rood, Brian R., Wang, Pei

Publikováno v: In Cell 23 December 2020 183(7):1962-1985

Ventricular apparent diffusion coefficient measurements in patients with neoplastic leptomeningeal disease

Autor: James M. Debnam, Ryan B. Said, Heng-Hsiao Liu, Jia Sun, Jihong Wang, Wei Wei, Dima Suki, Rory R. Mayer, T. Linda Chi, Leena Ketonen, Nandita Guha-Thakurta, Jeffrey S. Weinberg

Publikováno v: Cancer Imaging, Vol 20, Iss 1, Pp 1-11 (2020)

Abstract Background To test the hypothesis that intraventricular ADC values can be used to determine the presence of neoplastic leptomeningeal disease (LMD). Materials and methods ADC values were measured at multiple sites in the ventricular system i

Externí odkaz: https://doaj.org/article/f42071d60606493eab3b102e290c65ce

Phase 1 study of spinal cord constraint relaxation with single session spine stereotactic radiosurgery in the primary management of patients with inoperable, previously irradiated metastatic epidural spinal cord compression

Autor: Amol J Ghia, Nandita Guha-Thakurta, Juhee Song, Peter Thall, Tina M Briere, Stephen H Settle, Hadley J Sharp, Jing Li, MaryFrances McAleer, Eric L Chang, Claudio E Tatsui, Paul D Brown, Laurence D Rhines

Publikováno v: North American Spine Society Journal, Vol 6, Iss , Pp 100066- (2021)

Background: Patients with previously irradiated metastatic epidural spinal cord compression (MESCC) who are not surgical candidates are at high risk of neurologic deterioration due to disease in the setting of limited treatment options. We seek to es

Externí odkaz: https://doaj.org/article/1648ca4f321543d7ac18e2248bdefc9f