Zobrazeno 1 - 10
of 132
pro vyhledávání: '"A. Gerasyuto"'
Akademický článek
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Autor:
Jana Narasimhan, Suzanne Letinski, Stephen P Jung, Aleksey Gerasyuto, Jiashi Wang, Michael Arnold, Guangming Chen, Jean Hedrick, Melissa Dumble, Kanchana Ravichandran, Talya Levitz, Chang Cui, Catherine L Drennan, JoAnne Stubbe, Gary Karp, Arthur Branstrom
Publikováno v:
eLife, Vol 11 (2022)
Antibiotic-resistant Neisseria gonorrhoeae (Ng) are an emerging public health threat due to increasing numbers of multidrug resistant (MDR) organisms. We identified two novel orally active inhibitors, PTC-847 and PTC-672, that exhibit a narrow spectr
Externí odkaz:
https://doaj.org/article/e2f24e41f41645fe97c9ca6615d7120b
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 1170-1178 (2013)
A successful enone version of an intramolecular aza-[3 + 3] annulation reaction is described here. Use of piperidinium trifluoroacetate salt as the catalyst and toluene as the solvent appears to be critical for a successful annulation. We also demons
Externí odkaz:
https://doaj.org/article/f06ead3ec67d466dbc66d8c44ac1046e
Akademický článek
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Autor:
Jana Narasimhan, Suzanne Letinski, Stephen P Jung, Aleksey Gerasyuto, Jiashi Wang, Michael Arnold, Guangming Chen, Jean Hedrick, Melissa Dumble, Kanchana Ravichandran, Talya Levitz, Chang Cui, Catherine L Drennan, JoAnne Stubbe, Gary Karp, Arthur Branstrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242c3ecb2516113bcfac9a95f12d9626
https://doi.org/10.7554/elife.67447.sa2
https://doi.org/10.7554/elife.67447.sa2
Akademický článek
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Autor:
M. Dumble, Kanchana R. Ravichandran, Christopher J. Chang, Catherine L. Drennan, J. Hedrick, Michael Arnold, J. Wang, G. Chen, T. S. Levitz, S. Letinski, J. Narasimhan, A. Branstrom, A. Gerasyuto, Gary Mitchell Karp, JoAnne Stubbe, S. Jung
Antibiotic resistant Neisseria gonorrhoeae (Ng) are an emerging public health threat due to increasing numbers of multidrug resistant (MDR) organisms. We identified two novel orally active inhibitors, PTC-847 and PTC-672, that exhibit a narrow spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b47d759b4635c34c0cc90d75813787f
https://doi.org/10.1101/2020.11.19.389957
https://doi.org/10.1101/2020.11.19.389957
Autor:
Woll Matthew G, Marla Weetall, Jiashi Wang, Sean M. Smith, Arthur Branstrom, Aleksey I. Gerasyuto, Neil Gregory Almstead, Xiaoyan Zhang, Srinivasa Peddi, Guangming Chen, J V N Prasad, Nanjing Zhang, Jana Narasimhan, Josephine Sheedy, Michael Arnold, Melissa Dumble, Gary Mitchell Karp, John D. Baird
Publikováno v:
Journal of Medicinal Chemistry
There exists an urgent medical need to identify new chemical entities (NCEs) targeting multidrug resistant (MDR) bacterial infections, particularly those caused by Gram-negative pathogens. 4-Hydroxy-2-pyridones represent a novel class of nonfluoroqui
Autor:
Wu Yin, Zhe Nie, Karen Dingley, Michael Trzoss, Goran Krilov, Netonia Marshall, Shulu Feng, Robert Pelletier, Jeff Bell, Paul Devine, Peter Skrdla, Roman Shimanovich, Min Ye, David Calkins, Mary Grimes, Wayne Tang, Andrew Placzek, Morgan Lawrenz, Fiona McRobb, Aleksey Gerasyuto, Victoria Feher, Sayan Mondal, Kristian Jensen, Hamish Wright, Daniel Weiss, Karen Akinsanya
Publikováno v:
Blood. 138:1187-1187
Introduction: MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) is a key mediator of the NF-κB signaling pathway, the main driver of a subset of B-cell lymphomas and functions by forming a complex with CARMA1 and BCL10 to me
Autor:
Kristian Jensen, Wayne Tang, Mary Grimes, David Calkins, W. George Lai, Sayan Mondal, Victoria A. Feher, Jeff Bell, Wu Yin, Fiona M. McRobb, Shulu Feng, Michael Trzoss, Goran Krilov, Hamish Wright, Andrew Placzek, Robert Pelletier, Morgan Lawrenz, Nie Zhe, Aleksey Gerasyuto, Karen Akinsanya
Publikováno v:
Blood. 136:30-30
Introduction: MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1), was identified as a translocation protein fused with cIAP2 in mucosa-associated lymphoid tissue (MALT) B cell lymphomas. MALT1, a key mediator of NF-κB signali