Zobrazeno 1 - 10
of 1 133
pro vyhledávání: '"A. Gaiti"'
Publikováno v:
Stem Cell Research, Vol 79, Iss , Pp 103502- (2024)
Externí odkaz:
https://doaj.org/article/941c40d9be494ff1af245b3e2122b7d3
Autor:
Saravanan Ganesan, Mariela Cortés-López, Ariel D. Swett, Xiaoguang Dai, Scott Hickey, Paulina Chamely, Allegra G. Hawkins, Sissel Juul, Dan A. Landau, Federico Gaiti
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102966- (2024)
Summary: Studying RNA splicing factor mutations is challenging due to difficulties in distinguishing wild-type and mutant cells within complex human tissues and inaccuracies associated with reconstructing splicing signals from short-read sequencing d
Externí odkaz:
https://doaj.org/article/1a6555dac06745db9830feffe2205b45
Autor:
Gaiti Hasan
Publikováno v:
Contact, Vol 7 (2024)
All living organisms need to respond appropriately to changes in the extracellular milieu. Cellular mechanisms that enable such responses evolved in parallel with organismal complexity and intracellular Ca 2+ signaling is one such mechanism where ext
Externí odkaz:
https://doaj.org/article/4d3a9faade0c4fb8b0b737e8dfe6e766
Publikováno v:
eLife, Vol 12 (2024)
Maturation and fine-tuning of neural circuits frequently require neuromodulatory signals that set the excitability threshold, neuronal connectivity, and synaptic strength. Here, we present a mechanistic study of how neuromodulator-stimulated intracel
Externí odkaz:
https://doaj.org/article/25f86ec3d57f4e948fc547b00f357094
Autor:
Cortés-López, Mariela, Chamely, Paulina, Hawkins, Allegra G., Stanley, Robert F., Swett, Ariel D., Ganesan, Saravanan, Mouhieddine, Tarek H., Dai, Xiaoguang, Kluegel, Lloyd, Chen, Celine, Batta, Kiran, Furer, Nili, Vedula, Rahul S., Beaulaurier, John, Drong, Alexander W., Hickey, Scott, Dusaj, Neville, Mullokandov, Gavriel, Stasiw, Adam M., Su, Jiayu, Chaligné, Ronan, Juul, Sissel, Harrington, Eoghan, Knowles, David A., Potenski, Catherine J., Wiseman, Daniel H., Tanay, Amos, Shlush, Liran, Lindsley, Robert C., Ghobrial, Irene M., Taylor, Justin, Abdel-Wahab, Omar, Gaiti, Federico, Landau, Dan A.
Publikováno v:
In Cell Stem Cell 7 September 2023 30(9):1262-1281
Akademický článek
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Akademický článek
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Autor:
Pragnya Chakraborty, Bipan Kumar Deb, Vikas Arige, Thasneem Musthafa, Sundeep Malik, David I Yule, Colin W Taylor, Gaiti Hasan
Publikováno v:
eLife, Vol 12 (2023)
Loss of endoplasmic reticular (ER) Ca2+ activates store-operated Ca2+ entry (SOCE) by causing the ER localized Ca2+ sensor STIM to unfurl domains that activate Orai channels in the plasma membrane at membrane contact sites (MCS). Here, we demonstrate
Externí odkaz:
https://doaj.org/article/cb7de2cdcce24cca9ec2a6b6302e1887
Publikováno v:
Stem Cell Research, Vol 67, Iss , Pp 103033- (2023)
Phospholipase A2 group 6 (PLA2G6, iPLA2β or PARK14) gene encodes a calcium-independent group 6 phospholipase A2 enzyme and is associated with young-onset autosomal recessive Parkinson’s disease (PD). We generated human induced pluripotent stem cel
Externí odkaz:
https://doaj.org/article/738be464049541d5bf18c550277f0f85