Zobrazeno 1 - 10
of 68
pro vyhledávání: '"A. Gacek-Matthews"'
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Nonribosomal peptide synthetases (NRPSs) and polyketide synthetases (PKSs) play a pivotal role in the production of bioactive natural products, such as antibiotics and cytotoxins. Despite biomedical and pharmaceutical importance, the molecul
Externí odkaz:
https://doaj.org/article/2f185f66f2b14acda99479261788cd65
Autor:
Kim L. de Luca, Pim M. J. Rullens, Magdalena A. Karpinska, Sandra S. de Vries, Agnieszka Gacek-Matthews, Lőrinc S. Pongor, Gaëlle Legube, Joanna W. Jachowicz, A. Marieke Oudelaar, Jop Kind
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Accurate repair of DNA damage is critical for maintenance of genomic integrity and cellular viability. Because damage occurs non-uniformly across the genome, single-cell resolution is required for proper interrogation, but sensitive detectio
Externí odkaz:
https://doaj.org/article/4a8adea22a094f2e87579c732274e6d0
Akademický článek
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Autor:
Alice Rassinger, Agnieszka Gacek-Matthews, Joseph Strauss, Robert L. Mach, Astrid R. Mach-Aigner
Publikováno v:
Fungal Biology and Biotechnology, Vol 5, Iss 1, Pp 1-18 (2018)
Abstract Background The filamentous fungus Trichoderma reesei (T. reesei) is a natural producer of cellulolytic and xylanolytic enzymes and is therefore industrially used. Many industries require high amounts of enzymes, in particular cellulases. Str
Externí odkaz:
https://doaj.org/article/15152f3e06ff4b78b194424d98f2b732
Autor:
Simone Bachleitner, Jens Laurids Sørensen, Agnieszka Gacek-Matthews, Michael Sulyok, Lena Studt, Joseph Strauss
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Fungi produce a plethora of secondary metabolites (SMs) involved in cellular protection, defense, and signaling. Like other metabolic processes, transcription of SM biosynthesis genes is tightly regulated to prevent an unnecessary use of resources. G
Externí odkaz:
https://doaj.org/article/67185471771741b59ff294bb649bef43
Autor:
Juliane Fischer, Sebastian Y Müller, Tina Netzker, Nils Jäger, Agnieszka Gacek-Matthews, Kirstin Scherlach, Maria C Stroe, María García-Altares, Francesco Pezzini, Hanno Schoeler, Michael Reichelt, Jonathan Gershenzon, Mario KC Krespach, Ekaterina Shelest, Volker Schroeckh, Vito Valiante, Thorsten Heinzel, Christian Hertweck, Joseph Strauss, Axel A Brakhage
Publikováno v:
eLife, Vol 7 (2018)
The eukaryotic epigenetic machinery can be modified by bacteria to reprogram the response of eukaryotes during their interaction with microorganisms. We discovered that the bacterium Streptomyces rapamycinicus triggered increased chromatin acetylatio
Externí odkaz:
https://doaj.org/article/cafdcfa42f084b8b805c8be272eef709
Akademický článek
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Autor:
Eva Maria, Kalbhenn, Markus, Kranzler, Agnieszka, Gacek-Matthews, Gregor, Grass, Timo D, Stark, Elrike, Frenzel, Monika, Ehling-Schulz
Publikováno v:
International journal of molecular sciences. 23(19)
The emetic type of foodborne disease caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3667a600c0ddb1f2110d873eca803394
https://pubmed.ncbi.nlm.nih.gov/36232797
https://pubmed.ncbi.nlm.nih.gov/36232797
Autor:
Agnieszka Gacek-Matthews, Harald Berger, Takahiko Sasaki, Kathrin Wittstein, Clemens Gruber, Zachary A Lewis, Joseph Strauss
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006222 (2016)
Histone posttranslational modifications (HPTMs) are involved in chromatin-based regulation of fungal secondary metabolite biosynthesis (SMB) in which the corresponding genes-usually physically linked in co-regulated clusters-are silenced under optima
Externí odkaz:
https://doaj.org/article/71453a9162ee421db4b84364be82d55f
Autor:
Imrich Barák, Genia Lücking, Monika Ehling-Schulz, Michael Sulyok, Agnieszka Gacek-Matthews, Zuzana Chromiková
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
mBio
mBio
This study revealed a novel, potentially conserved mechanism involved in the biosynthesis of microbial natural products, exemplified by the mitochondrial active depsipeptide cereulide. Similar to other bioactive substances, such as the last-resort an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abbed4d520ff3b97ab7411a981e0047
https://doi.org/10.1128/mbio.01577-20
https://doi.org/10.1128/mbio.01577-20