Zobrazeno 1 - 10
of 503
pro vyhledávání: '"A. G. Tzioufas"'
Publikováno v:
Immuno, Vol 2, Iss 4, Pp 584-608 (2022)
Among other systemic autoimmune diseases, primary Sjögren syndrome (pSS) bears the highest risk for lymphoma development. In pSS, chronic antigenic stimulation gradually drives the evolution from polyclonal B-cell expansion to oligoclonal/monoclonal
Externí odkaz:
https://doaj.org/article/e01afe237a2a45219a0ca2c8220ae43e
Autor:
Georgios Boutzios, Sofia Chatzi, Andreas V. Goules, Areti Mina, George C. Charonis, Panayiotis G. Vlachoyiannopoulos, Athanasios G. Tzioufas
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundGraves’ orbitopathy (GO) is an autoimmune disorder affecting the orbital fat and muscles. A significant role of IL-6 in the pathogenesis of GO has been described and tocilizumab (TCZ), an IL-6 inhibitor targeting IL-6R has been given in s
Externí odkaz:
https://doaj.org/article/018118abfc404e99aaab786e23f79300
Autor:
Dimitris Anastasios Palamidas, Loukas Chatzis, Maria Papadaki, Ilias Gissis, Konstantinos Kambas, Evangelos Andreakos, Andreas V. Goules, Athanasios G. Tzioufas
Publikováno v:
Cells, Vol 13, Iss 5, p 430 (2024)
Giant cell arteritis (GCA) is an autoimmune disease affecting large vessels in patients over 50 years old. It is an exemplary model of a classic inflammatory disorder with IL-6 playing the leading role. The main comorbidities that may appear acutely
Externí odkaz:
https://doaj.org/article/6bc057735e2a4153aeef669dda488bd5
Autor:
Vasileios C. Pezoulas, Andreas Goules, Fanis Kalatzis, Luke Chatzis, Konstantina D. Kourou, Aliki Venetsanopoulou, Themis P. Exarchos, Saviana Gandolfo, Konstantinos Votis, Evi Zampeli, Jan Burmeister, Thorsten May, Manuel Marcelino Pérez, Iryna Lishchuk, Thymios Chondrogiannis, Vassiliki Andronikou, Theodora Varvarigou, Nenad Filipovic, Manolis Tsiknakis, Chiara Baldini, Michele Bombardieri, Hendrika Bootsma, Simon J. Bowman, Muhammad Shahnawaz Soyfoo, Dorian Parisis, Christine Delporte, Valérie Devauchelle-Pensec, Jacques-Olivier Pers, Thomas Dörner, Elena Bartoloni, Roberto Gerli, Roberto Giacomelli, Roland Jonsson, Wan-Fai Ng, Roberta Priori, Manuel Ramos-Casals, Kathy Sivils, Fotini Skopouli, Witte Torsten, Joel A. G. van Roon, Mariette Xavier, Salvatore De Vita, Athanasios G. Tzioufas, Dimitrios I. Fotiadis
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 471-484 (2022)
For many decades, the clinical unmet needs of primary Sjögren’s Syndrome (pSS) have been left unresolved due to the rareness of the disease and the complexity of the underlying pathogenic mechanisms, including the pSS-associated lymphomagenesis pr
Externí odkaz:
https://doaj.org/article/b16981d4192d4498a244cd7bedcee6c8
Autor:
Panagiotis K. Panagopoulos, Andreas V. Goules, Vasiliki E. Georgakopoulou, Anastasios Kallianos, Eirini Chatzinikita, Vasileios C. Pezoulas, Katerina Malagari, Dimitrios I. Fotiadis, Panayiotis Vlachoyiannopoulos, Theodoros Vassilakopoulos, Athanasios G. Tzioufas
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundA number of studies report small airways involvement in patients with systemic sclerosis (SSc). Furthermore, small airways dysfunction is increasingly recognized in patients with interstitial lung disease (ILD) of idiopathic or autoimmune e
Externí odkaz:
https://doaj.org/article/28f5a7fa51184eb9a132b77905a187e9
Autor:
Theodoros Androutsakos, Theodoros A. Voulgaris, Athanasios-Dimitrios Bakasis, Maria-Loukia Koutsompina, Loukas Chatzis, Ourania D. Argyropoulou, Vasilis Pezoulas, Dimitrios I. Fotiadis, George Papatheodoridis, Athanasios G. Tzioufas, Andreas V. Goules
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPrimary Sjögren syndrome (pSS) is a systemic autoimmune epithelitis, potentially affecting salivary epithelium, biliary epithelium, and hepatocytes. Common immunological mechanisms might cause clinically silent liver inflammation, and comb
Externí odkaz:
https://doaj.org/article/5a61800ba43e4b33a673d78a3f709f5e
Autor:
Vasileios C. Pezoulas, Costas Papaloukas, Maëva Veyssiere, Andreas Goules, Athanasios G. Tzioufas, Vassili Soumelis, Dimitrios I. Fotiadis
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3058-3068 (2021)
Unlike autoimmune diseases, there is no known constitutive and disease-defining biomarker for systemic autoinflammatory diseases (SAIDs). Kawasaki disease (KD) is one of the “undiagnosed” types of SAIDs whose pathogenic mechanism and gene mutatio
Externí odkaz:
https://doaj.org/article/c17da14ac0f845e686a0065bae108146
Autor:
Georgios Boutzios, Eleni Koukoulioti, Andreas V. Goules, Ioannis Kalliakmanis, Ilias Giovannopoulos, Panayiotis Vlachoyiannopoulos, Haralampos M. Moutsopoulos, Athanasios G. Tzioufas
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundHashimoto thyroiditis (HT) is an autoimmune disease which may result in extensive damage of the thyroid gland. Chronic atrophic gastritis (CAG), is the most frequent HT-associated disorder, with anti-parietal cell autoantibodies (APCA) bein
Externí odkaz:
https://doaj.org/article/1bd115ffc3e44640bf39f9163000fc46
Autor:
Konstantina D. Kourou, Vasileios C. Pezoulas, Eleni I. Georga, Themis Exarchos, Costas Papaloukas, Michalis Voulgarelis, Andreas Goules, Andrianos Nezos, Athanasios G. Tzioufas, Earalampos M. Moutsopoulos, Clio Mavragani, Dimitrios I. Fotiadis
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 1, Pp 49-56 (2020)
Lymphoma development constitutes one of the most serious clinico-pathological manifestations of patients with Sjögren's Syndrome (SS). Over the last decades the risk for lymphomagenesis in SS patients has been studied aiming to identify novel bioma
Externí odkaz:
https://doaj.org/article/2d633b63df074461851f80840e7a0cf9
Autor:
Vasileios C. Pezoulas, Konstantina D. Kourou, Fanis Kalatzis, Themis P. Exarchos, Evi Zampeli, Saviana Gandolfo, Andreas Goules, Chiara Baldini, Fotini Skopouli, Salvatore De Vita, Athanasios G. Tzioufas, Dimitrios I. Fotiadis
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 1, Pp 83-90 (2020)
Goal: To present a framework for data sharing, curation, harmonization and federated data analytics to solve open issues in healthcare, such as, the development of robust disease prediction models. Methods: Data curation is applied to remove data inc
Externí odkaz:
https://doaj.org/article/f4fa2243396d407cbf1684c54718fd00