Zobrazeno 1 - 10
of 33
pro vyhledávání: '"A. G. Tatosyan"'
Autor:
Elena M. Tchevkina, Anna Martinjuk, Andrei Komelkov, Natalya Dyakova, Larisa Agapova, A. G. Tatosyan
Publikováno v:
Oncogene. 24:329-335
RAS oncogenes play a critical role in oncogenic transformation and metastases formation. Here we show that Ha-ras greatly stimulates spontaneous metastatic activity of transformed cells through the Ras/RalGDS/RalA intracellular signaling pathway. Int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17642149dba711b83a6d2db5f98e208b
https://doi.org/10.1038/sj.onc.1208094
https://doi.org/10.1038/sj.onc.1208094
Autor:
I. B. Zborovskaya, A. G. Tatosyan
Publikováno v:
Molecular Biology. 38:155-164
Studies performed in the recent decade in the Laboratory of the Regulation of Cell and Virus Oncogenes associated structural and functional defects of several oncogenes and tumor suppressor genes with various stages of non-small-cell lung cancer. Hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b90ed4bd390e74f235ef0f8bec86ea2
https://doi.org/10.1023/b:mbil.0000023729.73314.84
https://doi.org/10.1023/b:mbil.0000023729.73314.84
Publikováno v:
Russian Journal of Genetics. 39:571-577
Allele distribution at a highly polymorphic minisatellite adjacent to the c-Hras1 gene as well as deletions of microsatellite markers, D3S966, D3S1298, D9S171, and a microsatellite within p53 gene, were examined in bronchial epithelium specimens obta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2a0952aa3a0466e55f9d0d5177f52a0
https://doi.org/10.1023/a:1023791902747
https://doi.org/10.1023/a:1023791902747
Autor:
Maria V. Samsonova, Ekaterina Y. Steshina, Svetlana Yu. Chikina, Andrei Chernyaev, Alexander G. Chuchalin, I. B. Zborovskaya, Victor V. Chizhikov, Guram Ungiadze, Alexander V. Gasparian, A. G. Tatosyan
Publikováno v:
Oncogene. 21:2398-2405
Ionizing radiation is a potent lung carcinogen, but the precise molecular damage associated with it is still unknown. In this study we investigated cancer-related molecular abnormalities including K-ras (codon 12) mutation, p16(INK4A) promoter hyperm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd05cdcbac09de4faf8385fca2e170f
https://doi.org/10.1038/sj.onc.1205310
https://doi.org/10.1038/sj.onc.1205310
Publikováno v:
Molecular Biology. 36:370-375
Hamster tumor cell lines obtained with the Rous sarcoma virus and characterized by a high metastatic activity in vitro were transfected with the gene for Ca2+/calmodulin-dependent serine–threonine death-associated protein kinase (DAPk). Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc4e29e6b356c606266fb9e1ff6c830
https://doi.org/10.1023/a:1016007329183
https://doi.org/10.1023/a:1016007329183
Autor:
Olga A. Mizenina, Yuriy G. Yanushevich, Jacques Camonis, Jean de Gunzburg, Anna Rodina, Michail A. Krasilnikov, Armand Tavitian, Elena Musatkina, A. G. Tatosyan
Publikováno v:
Journal of Biological Chemistry. 276:34006-34012
We have isolated a novel isoform of phospholipase A(2). This enzyme was designated srPLA(2) because it was discovered while analyzing the proteins interacting with different forms of the v-Src oncoproteins isolated from Rous sarcoma virus-transformed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf95de97827977ce4901a845757fe76
https://doi.org/10.1074/jbc.m011320200
https://doi.org/10.1074/jbc.m011320200
Autor:
I. B. Zborovskaya, Boris E. Polotskii, Vera Delektorskaya, Konstantin Laktionov, Alexander V. Gasparian, A. G. Tatosyan, Victor Chizhikov
Publikováno v:
Molecular Carcinogenesis. 30:151-158
Allelic losses at 1p32-pter have been reported as frequent events in human non-small cell lung cancer (NSCLC). To further characterize the region of deletions, we studied loss of heterozygosity on a panel of 102 microdissected NSCLC samples with 20 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe9fec8d3f8676361cb971c334f7724
https://doi.org/10.1002/mc.1023
https://doi.org/10.1002/mc.1023
Publikováno v:
Molecular Biology. 34:772-775
The method of differential display of cDNA produced on the RNA from highly and poorly metastasizing cell lines revealed a number of genes with different expression depending on the metastatic potential. An mRNA corresponding to one of these cDNA frag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3720546b476782bc8da9fa4e84faeded
https://doi.org/10.1007/bf02759623
https://doi.org/10.1007/bf02759623
Publikováno v:
Molecular Biology. 34:403-407
We studied the relation between genetic anomalies in thep73 gene encoding a product structurally and functionally similar to the protein p53 and the pathogenesis of non-small-cell lung carcinoma (NSCLC; 83 patients). Loss of one of thep73 alleles was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3168e17994706d54b3f546dbdc5a65
https://doi.org/10.1007/bf02759672
https://doi.org/10.1007/bf02759672
Autor:
L. M. Kashkina, Mikhail A. Nikiforov, Andrei Komelkov, Andrei V. Gudkov, Natalia A. Dyakova, Nicolai E. Kushlinsky, Olga Mizenina, A. G. Tatosyan, G. I. Deichman, Marina O. Prilutskaya, Erna G. Gorojanskaya
Publikováno v:
International Journal of Cancer. 66:747-752
We have previously demonstrated that hamster embryo fibroblasts (HEFs) transformed by Rous Sarcoma virus, Schmidt-Ruppin strain (RSV-SR) are highly resistant to damage by H 2 O 2 (H 2 O 2 R ), (in contrast to HEFs transformed spontaneously, or by bov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d8653217f07ebb9549b423256ae5434
https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<747::aid-ijc7>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<747::aid-ijc7>3.0.co