Zobrazeno 1 - 10
of 41
pro vyhledávání: '"A. G. Mezhlumyan"'
Autor:
A. G. Mezhlumyan, A. V. Tallerova, P. Yu. Povarnina, N. M. Sazonova, A. V. Tarasiuk, T. A. Gudasheva
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 11-17 (2020)
At the Zakusov Institute of Pharmacology designed and synthesized dimeric dipeptide mimetics of the 1st (GK-6) and 4th (GK-2) nerve growth factor loops, 1st (GSB-214), 2nd (GTS-201) and 4th (GSB -106, GSB-106Ac) brain-derived neurotrophic factor loop
Externí odkaz:
https://doaj.org/article/d4dfcd3deb5448cbb115f2500a9500cc
Autor:
Armen G. Mezhlumyan, Anna V. Tallerova, Polina Y. Povarnina, Aleksey V. Tarasiuk, Nellya M. Sazonova, Tatiana A. Gudasheva, Sergey B. Seredenin
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 284 (2022)
Neurotrophins are considered as an attractive target for the development of antidepressants with a novel mechanism of action. Previously, the dimeric dipeptide mimetics of individual loops of nerve growth factor, NGF (GK-6, loop 1; GK-2, loop 4) and
Externí odkaz:
https://doaj.org/article/d59c9dd10e184a8bb8ce4f2d39ea3d64
Autor:
Tatiana A. Gudasheva, Anna V. Tallerova, Armen G. Mezhlumyan, Tatyana A. Antipova, Ilya O. Logvinov, Yulia N. Firsova, Polina Y. Povarnina, Sergey B. Seredenin
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 252 (2021)
A mimetic of the BDNF loop 4, bis (N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide, named GSB-106, was designed and synthesized in our scientific group. The compound activated TrkB, MAPK/ERK, PI3K/AKT, and PLCγ in in vitro experiments. In vivo
Externí odkaz:
https://doaj.org/article/fd6b301f445d496195370eaf3ae8921a
Autor:
L. G. Mezhlumyan, I. L. Khikmatullaev, Sh. Kh. Rakhimova, D. A. Narbutaeva, S. M. Yusupova, S. F. Aripova
Publikováno v:
Chemistry of Natural Compounds. 58:187-189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1fa55922d8d445ba5ad4086b753a278
https://doi.org/10.1007/s10600-022-03631-y
https://doi.org/10.1007/s10600-022-03631-y
Publikováno v:
Pharmaceutical Chemistry Journal. 55:101-105
Antidepressant activities of the original compounds GSB-106 [bis(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide], a mimetic of the fourth loop of brain-derived neurotrophic factor (BDNF); GML-3(N-butyl-N-methyl-1-phenylpyrrolo[1,2-a]pyrazine-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e18bcc17203adef7d819015a7072fe2
https://doi.org/10.1007/s11094-021-02397-x
https://doi.org/10.1007/s11094-021-02397-x
Autor:
A. E. Eshbekov, S. D. Gusakova, L. G. Mezhlumyan, Sh. K. Khidoyatova, M. Kh. Malikova, R. K. Rakhmanberdyeva
Publikováno v:
Chemistry of Natural Compounds. 57:1-5
The carbohydrate, lipid, and protein contents of Phaseolus vulgaris L. pods during the milk-ripe and fruit-ripening stages were studied and their compositions and physicochemical parameters were established. The content of water-soluble polysaccharid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43003a598371d409d98e7b6be77bc1d1
https://doi.org/10.1007/s10600-021-03266-5
https://doi.org/10.1007/s10600-021-03266-5
Autor:
A. G. Mezhlumyan, T. A. Antipova, T. A. Gudasheva, Anna V. Tallerova, P. Yu. Povarnina, I. O. Logvinov, S. B. Seredenin
Publikováno v:
Pharmaceutical Chemistry Journal. 54:431-434
The influence of the dimeric dipeptide mimetic of brain-derived neurotrophic factor (BDNF) bis(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide (GSB-106, dosage form) during three-day peroral administration at a dose of 0.1 mg/kg on the 1% sucro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f4095770aee2814011156b2047702d5
https://doi.org/10.1007/s11094-020-02217-8
https://doi.org/10.1007/s11094-020-02217-8
Autor:
I. O. Logvinov, Armen G. Mezhlumyan, Anna V. Tallerova, Polina Povarnina, Tatiana A Gudasheva, T. A. Antipova, Yulia N. Firsova, Sergey B. Seredenin
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 252, p 252 (2021)
Volume 11
Issue 2
Biomolecules, Vol 11, Iss 252, p 252 (2021)
Volume 11
Issue 2
A mimetic of the BDNF loop 4, bis (N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide, named GSB-106, was designed and synthesized in our scientific group. The compound activated TrkB, MAPK/ERK, PI3K/AKT, and PLCγ in in vitro experiments. In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69eb52d7a4f0292879db9b4820262a3a
https://pubmed.ncbi.nlm.nih.gov/33578683
https://pubmed.ncbi.nlm.nih.gov/33578683
Autor:
L. G. Mezhlumyan, Sh. Kh. Rakhimova, Z. A. Khushbaktova, U. Sh. Ishimov, D. A. Narbutaeva, N. Sh. Azimov, S. F. Aripova
Publikováno v:
Chemistry of Natural Compounds. 57:599-600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::789dc50b9d8ae3ff66313d2d87487fa7
https://doi.org/10.1007/s10600-021-03430-x
https://doi.org/10.1007/s10600-021-03430-x
Publikováno v:
Chemistry of Natural Compounds. 57:597-598
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::625249190b337d9d3dfa26ef45de9db8
https://doi.org/10.1007/s10600-021-03429-4
https://doi.org/10.1007/s10600-021-03429-4