Zobrazeno 1 - 10
of 111
pro vyhledávání: '"A. G. Iyevleva"'
Autor:
G. A. Yanus, A. G. Iyevleva, E. N. Suspitsin, A. V. Tumakova, E. V. Belogubova, S. N. Aleksakhina, A. V. Togo, E. N. Imyanitov
Publikováno v:
Сеченовский вестник, Vol 14, Iss 2, Pp 5-20 (2023)
Kidney cancer (KC) is a common disease characterized by extreme heterogeneity. There are nine known monogenic diseases associated with a significantly elevated KC risk: von Hippel-Lindau disease, MET-associated papillary renal cancer, familial multip
Externí odkaz:
https://doaj.org/article/824ae3fb06854f82907ac808d22b6d45
Autor:
N. V. Mitiushkina, I. A. Stepanov, D. O. Yurlov, E. A. Filippova, S. V. Odintsova, A. M. Lozhkina, S. V. Orlov, A. G. Iyevleva
Publikováno v:
Сибирский онкологический журнал, Vol 19, Iss 4, Pp 132-137 (2020)
Introduction. Translocations of ALK receptor tyrosine kinase occur in approximately 5–9 % of lung adenocarcinomas. The use of ALK inhibitors usually results in the reduction of tumor size. Nevertheless, the extent and duration of response can vary
Externí odkaz:
https://doaj.org/article/031eb41cb88046efac51b21b066f0b82
Autor:
D. V. Pashkov, A. R. Venina, A. O. Ivantsov, G. A. Yanus, G. A. Raskin, E. N. Imyanitov, S. E. Kubrina, A. D. Mikushina, G. M. Manikhas, E. V. Ponomareva, I. I. Dzidzava, A. G. Iyevleva
Publikováno v:
Сибирский онкологический журнал, Vol 19, Iss 1, Pp 31-39 (2020)
Background. Tumors demonstrating the phenomenon of microsatellite instability (MSI) represent a special category of colorectal cancer (CRC). Such neoplasms account for up to 20 % of CRC and are characterized by specific molecular and clinical manifes
Externí odkaz:
https://doaj.org/article/ea66271a35ba42a88fcb321f821f2e0b
Autor:
M. V. Matsko, D. E. Matsko, N. M. Volkov, A. Yu. Ulitin, V. M. Moiseenko, E. N. Imyanitov, A. G. Iyevleva
Publikováno v:
Сибирский онкологический журнал, Vol 18, Iss 3, Pp 34-44 (2019)
Primary glioblastoma (GB) is a rapidly progressing central nervous system tumor with aggressive biological behavior. Long-term glioblastoma survival, defined as survival beyond 3 years, is a rare phenomenon. Various factors contributing to such prolo
Externí odkaz:
https://doaj.org/article/0d4f0d5f247d49c4910fcc0be2154a1f
Publikováno v:
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 25, Iss 2, Pp 7-18 (2018)
Hereditary breast and ovarian cancer is one of the most common genetic pathology. Medical and genetic counseling of patients with hereditary breast and ovarian cancer and their families plays the important role in cancer care, as it helps to develop
Externí odkaz:
https://doaj.org/article/445fa1669c4449ecb2bec7f557f6851f
Autor:
K. B. Kotiv, T. V. Gorodnova, A. O. Ivantsov, A. G. Iyevleva, S. N. Aleksakhina, G. M. Manichas, A. S. Lisyanskaya, R. P. Salomatov, M. S. Shushaniia, M. V. Borodenko, L. D. Roman, G. I. Mikhailiuk, O. N. Mikheeva, T. G. Grigorieva, I. V. Berlev, E. N. Imyanitov, A. P. Sokolenko
Publikováno v:
Сибирский онкологический журнал, Vol 16, Iss 6, Pp 31-40 (2017)
Germ-line mutations in BRCA1 and BRCA2 genes are the most established risk factors for hereditary breast and ovarian cancers. The purpose of the study was to analyze BRCA1/2 testing in ovarian cancer patients. Materials and methods. We analyzed 222 p
Externí odkaz:
https://doaj.org/article/31f595ac4f1a4d64a72ee96e73f7dd63
Autor:
Aleksandr A. Romanko, Rimma S. Mulkidjan, Vladislav I. Tiurin, Evgeniya S. Saitova, Elena V. Preobrazhenskaya, Elena A. Krivosheyeva, Natalia V. Mitiushkina, Anna D. Shestakova, Evgeniya V. Belogubova, Alexandr O. Ivantsov, Aglaya G. Iyevleva, Evgeny N. Imyanitov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14203 (2023)
The majority of NTRK1, NTRK2, and NTRK3 rearrangements result in increased expression of the kinase portion of the involved gene due to its fusion to an actively transcribed gene partner. Consequently, the analysis of 5′/3′-end expression imbalan
Externí odkaz:
https://doaj.org/article/97a6f0cc85ef4f67a0b3ccc368ba5d70
Autor:
Vladislav I. Tiurin, Elena V. Preobrazhenskaya, Natalia V. Mitiushkina, Aleksandr A. Romanko, Aleksandra A. Anuskina, Rimma S. Mulkidjan, Evgeniya S. Saitova, Elena A. Krivosheyeva, Elena D. Kharitonova, Mikhail P. Shevyakov, Ilya A. Tryakin, Svetlana N. Aleksakhina, Aigul R. Venina, Tatiana N. Sokolova, Aleksandr S. Martianov, Anna D. Shestakova, Alexandr O. Ivantsov, Aglaya G. Iyevleva, Evgeny N. Imyanitov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10530 (2023)
RET-kinase-activating gene rearrangements occur in approximately 1–2% of non-small-cell lung carcinomas (NSCLCs). Their reliable detection requires next-generation sequencing (NGS), while conventional methods, such as immunohistochemistry (IHC), fl
Externí odkaz:
https://doaj.org/article/ed3b25190915448b95cf3beca4b1f854
Autor:
Tatiana N. Sokolova, Svetlana N. Aleksakhina, Grigoriy A. Yanus, Aleksandr V. Sultanbaev, Konstantin V. Menshikov, Anna N. Lysenko, Ruslan A. Zukov, Alena V. Zyuzyukina, Yulia N. Murunova, Elena I. Rossokha, Sergey Y. Bakharev, Elena A. Basova, Tatiana A. Kasmynina, Irina S. Shumskaya, Yana I. Bakshun, Khedi S. Musaeva, Alfia I. Khasanova, Vadim N. Dmitriev, Marina B. Bolieva, Christina H. Gadzaova, Oleg L. Petrenko, Dmitriy A. Maksimov, Vladimir I. Vladimirov, Viktor E. Goldberg, Nataliya O. Popova, Marianna V. Kibisheva, Zaur M. Khamgokov, Alexey E. Vasilyev, Aglaya G. Iyevleva, Evgeny N. Imyanitov
Publikováno v:
Современная онкология, Vol 23, Iss 1, Pp 61-67 (2021)
Relevance. PIK3CA belongs to the top three most frequently mutated genes in breast cancer (BC), especially in estrogen receptor (ER) positive, HER2 negative BC subtype. With an approval of selective PI3K-alpha inhibitor, alpelisib, this alteration ha
Externí odkaz:
https://doaj.org/article/49ac17b627194a6ea7e6222ff26d5a94
Autor:
Aleksandr S. Martianov, Natalia V. Mitiushkina, Anastasia N. Ershova, Darya E. Martynenko, Mikhail G. Bubnov, Priscilla Amankwah, Grigory A. Yanus, Svetlana N. Aleksakhina, Vladislav I. Tiurin, Aigul R. Venina, Aleksandra A. Anuskina, Yuliy A. Gorgul, Anna D. Shestakova, Mikhail A. Maidin, Alexey M. Belyaev, Liliya S. Baboshkina, Aglaya G. Iyevleva, Evgeny N. Imyanitov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4868 (2023)
This study aimed to analyze clinical and regional factors influencing the distribution of actionable genetic alterations in a large consecutive series of colorectal carcinomas (CRCs). KRAS, NRAS and BRAF mutations, HER2 amplification and overexpressi
Externí odkaz:
https://doaj.org/article/a169542c441740c8ad3333e7f0a1b1f3