Zobrazeno 1 - 10
of 109
pro vyhledávání: '"A. G. Demaine"'
Autor:
Patricia Balaresque, Georgina R Bowden, Susan M Adams, Ho-Yee Leung, Turi E King, Zoë H Rosser, Jane Goodwin, Jean-Paul Moisan, Christelle Richard, Ann Millward, Andrew G Demaine, Guido Barbujani, Carlo Previderè, Ian J Wilson, Chris Tyler-Smith, Mark A Jobling
Publikováno v:
PLoS Biology, Vol 8, Iss 1, p e1000285 (2010)
The relative contributions to modern European populations of Paleolithic hunter-gatherers and Neolithic farmers from the Near East have been intensely debated. Haplogroup R1b1b2 (R-M269) is the commonest European Y-chromosomal lineage, increasing in
Externí odkaz:
https://doaj.org/article/19f7fca69e5141dfabba525748e440e9
Publikováno v:
Journal of Endocrinology and Diabetes. 3:1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cb72994fb6e189948c0fc14c328c82e
https://doi.org/10.15226/2374-6890/3/6/00167
https://doi.org/10.15226/2374-6890/3/6/00167
Autor:
Annwyne Houldsworth, Andy G. Demaine, E Kaminski, Magdalena Metzner, Steve Shaw, Matthew E. Cramp
Publikováno v:
Journal of Medical Virology. 86:941-947
Hepatitis C virus (HCV) is a pathogen causing chronic hepatitis, cirrhosis, and liver cancer occurring in about 3% of the world's population. Most individuals infected with HCV develop persistent viremia. Oxidative stress may play an important role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f5c6dea18bd723d4e8669036d0eccc0
https://doi.org/10.1002/jmv.23923
https://doi.org/10.1002/jmv.23923
Autor:
Matthew E. Cramp, Annwyne Houldsworth, Andrea Hodgkinson, Andrew G. Demaine, E. R. Kaminski, Magdalena Metzner
Publikováno v:
Journal of Medical Virology. 86:162-168
Several cell surface molecules have hepatitis C virus (HCV) binding properties and may serve as receptors facilitating viral entry into cells. The large extracellular loop (LEL) of CD81 has been shown to bind the HCV envelope protein E2 with several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13a0d6e8f80ffdd4f5f85f0ba6aaa077
https://doi.org/10.1002/jmv.23726
https://doi.org/10.1002/jmv.23726
Publikováno v:
Transplant Immunology. 25:16-19
Reactive oxygen species (ROS) such as superoxide (O(2)(-)) play important roles in inflammatory processes. By altering the redox environment, ROS modulate the activation of transcription factors and cytokine genes involved in acute cellular rejection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081f3c9cb8b50d40c11fc2f3377344a9
https://doi.org/10.1016/j.trim.2011.05.005
https://doi.org/10.1016/j.trim.2011.05.005
Publikováno v:
International Journal of Diabetes Mellitus. 2(3):169-174
Aims To investigate whether high glucose induces myo-inositol oxygenase (MIOX) expression in peripheral blood mononuclear cells through transcription factors, nuclear factor of activated T cells 5 (NFAT5) and carbohydrate response element binding pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cefd3d2bb34d6992a135bfad8ba6e3
Publikováno v:
Journal of Interferon & Cytokine Research. 30:59-66
Type 1 diabetes is an autoimmune disease that is caused by destruction of pancreatic beta-cells. Type 1 diabetes is a heterogenic disease with environmental factors as well as genetic components. It is well established that environmental factors can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670d841b358559c5bc959cef0b782063
https://doi.org/10.1089/jir.2009.0026
https://doi.org/10.1089/jir.2009.0026
Autor:
PH Thurairajah, E. R. Kaminski, Nikolai V. Naoumov, Doha Hegazy, Shilpa Chokshi, Andrew G. Demaine, Matthew E. Cramp, Steve Shaw
Publikováno v:
The Journal of Infectious Diseases. 198:1749-1755
Background. Injection drug users (IDUs) are at risk of acquiring hepatitis C virus (HCV) infection. We have identified a cohort of long-term IDUs who remain uninfected by HCV despite high-risk behavior. We have categorized these subjects as “expose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d52bc73e12ec4d23d0526c9e7190e49
https://doi.org/10.1086/593337
https://doi.org/10.1086/593337
Autor:
Michael J. McMahon, Derek A. O'Reilly, Michael Larvin, Mark T Cartmell, Andrew N. Kingsnorth, Andrew G. Demaine, Sakhawat H. Rahman, Andreas Kage, Michael Becker, Olfert Landt, Kevin Sargen, Heiko Witt, Hans-Ulrich Schulz
Publikováno v:
European Journal of Gastroenterology & Hepatology. 20:726-731
Acute pancreatitis (AP) is a disease whose pathogenesis remains largely obscure. Genetic research has focussed attention upon the role of the pancreatic protease/protease inhibitor system. The aim of this study was to investigate the prevalence of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ec0ba9e578834685b459dca383cdd5
https://doi.org/10.1097/meg.0b013e3282f5728c
https://doi.org/10.1097/meg.0b013e3282f5728c
Autor:
Annwyne Houldsworth, D. Hegazy, Andy G. Demaine, PH Thurairajah, E. R. Kaminski, Matthew E. Cramp, Steve Shaw, Magdalena Metzner
Publikováno v:
Clinical and Experimental Immunology. 152:538-541
Summary Cellular immunity with interferon gamma production could have a role in protection from hepatitis C virus (HCV). Interleukin (IL)-12 is a key cytokine in promoting such anti-viral T helper 1 (Th1) responses. We hypothesized that a genetic bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d608b11159d077de85e9f2c1dcce06d6
https://doi.org/10.1111/j.1365-2249.2008.03655.x
https://doi.org/10.1111/j.1365-2249.2008.03655.x