Zobrazeno 1 - 10
of 81
pro vyhledávání: '"A. G. Bukrinskaya"'
Publikováno v:
Molecular Biology. 45:811-815
HIV-1 matrix protein (MA) is a multifunctional structural protein located on the N-terminus of Gag precursor p55 and is responsible for its transport to the plasma membrane, the site of virus assembly. In the present paper, it has been shown that MA
Autor:
Michael Bukrinsky, A. G. Bukrinskaya
Publikováno v:
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology. 1:271-277
On entering a host cell, genomic components of human immunodeficiency virus (HIV) are translocated from plasma membrane to cell nucleus where the key events of the infectious process—virus genome integration into cell chromosomes and provirus forma
Publikováno v:
Doklady Biological Sciences. 408:249-252
Autor:
Sergey I. Lupandin, Valentina A. Divocha, Anatoliy I. Gozhenko, Galina K. Vorkunova, Alissa G. Bukrinskaya
Publikováno v:
World Journal of AIDS. :33-35
HIV-1 matrix protein (MA) is a multifunctional structural protein localized on N terminus of Gag precursor p55. MA participates in HIV-1 assembly as membranotropic part of Gag precursor as well as an individual protein spliced from Gag early in infec
Autor:
A. G. Bukrinskaya
Publikováno v:
Archives of Virology. 149:1067-1082
HIV-1 particles have been studied by structural and chemical approaches, however, the processes of assembly, budding and maturation are just beginning to be characterized, and molecular details of these processes remain poorly defined. This brief rev
Autor:
Ching-Man A. Virbasius, Natalia Sharova, Alissa G. Bukrinskaya, Xiaochun Zhu, Mario Stevenson, Michael R. Green, Caryn DeHoratius, Stefan A. Dupont
Publikováno v:
Nature. 402:681-685
An important aspect of the pathophysiology of human immunodeficiency virus type-1 (HIV-1) infection is the ability of the virus to replicate in non-dividing cells1,2,3. HIV-1 matrix (MA), the amino-terminal domain of the Pr55 gag polyprotein (Pr55),
Autor:
A. G. Bukrinskaya, V.V. Jdanov, N.K. Sharova, T.V. Khakhulina, O.P. Bogdan, I.V. Alymova, M.E. Burstein, A. Serbin, L.L. Stotskaya, E.E. Manukchina
Publikováno v:
Antiviral Research. 41:135-144
Newly developed antiviral compounds consisting of an adamantane derivative chemically linked to a water-soluble polyanionic matrix were shown to inhibit HIV-1 infection in lymphoblastoid cells, HeLa CD4+ beta-galactosidase (MAGI) cells and macrophage
Publikováno v:
The Journal of Experimental Medicine
After interaction of human immunodeficiency virus type 1 (HIV-1) virions with cell surface receptors, a series of poorly characterized events results in establishment of a viral reverse transcription complex in the host cell cytoplasm. This process i
Autor:
Thomas E. Smithgall, Alice G. Bukrinskaya, Robert E. Lewis, Anuja Ghorpade, Nina K. Heinzinger, Mario Stevenson
Publikováno v:
Proceedings of the National Academy of Sciences. 93:367-371
In the replication of human immunodeficiency virus type 1 (HIV-1), gag MA (matrix), a major structural protein of the virus, carries out opposing targeting functions. During virus assembly, gag MA is cotranslationally myristoylated, a modification re
Autor:
Koen Verhoef, A E Greijer, A G Bukrinskaya, J. L. B. Van Wamel, Sabine E.C. Koken, Ben Berkhout
Publikováno v:
Journal of biological chemistry, 269(11), 8366-8375. American Society for Biochemistry and Molecular Biology Inc.
Human immunodeficiency viruses HIV-1 and HIV-2 encode a Tat protein that specifically activates transcription from the viral long terminal repeat. To characterize the properties of the Tat proteins, we have expressed them in Escherichia coli. The pur