Zobrazeno 1 - 10
of 4 616
pro vyhledávání: '"A. Follmann"'
Autor:
Gilbert, Peter B., Peng, James, Han, Larry, Lange, Theis, Lu, Yun, Nie, Lei, Shih, Mei-Chiung, Waddy, Salina P., Wiley, Ken, Yann, Margot, Zafari, Zafar, Ghosh, Debashis, Follmann, Dean, Juraska, Michal, Díaz, Iván
For many rare diseases with no approved preventive interventions, promising interventions exist, yet it has been difficult to conduct a pivotal phase 3 trial that could provide direct evidence demonstrating a beneficial effect on the target disease o
Externí odkaz:
http://arxiv.org/abs/2407.06350
Autor:
Lindsay N. Carpp, Ollivier Hyrien, Youyi Fong, David Benkeser, Sanne Roels, Daniel J. Stieh, Ilse Van Dromme, Griet A. Van Roey, Avi Kenny, Ying Huang, Marco Carone, Adrian B. McDermott, Christopher R. Houchens, Karen Martins, Lakshmi Jayashankar, Flora Castellino, Obrimpong Amoa-Awua, Manjula Basappa, Britta Flach, Bob C. Lin, Christopher Moore, Mursal Naisan, Muhammed Naqvi, Sandeep Narpala, Sarah O’Connell, Allen Mueller, Leo Serebryannyy, Mike Castro, Jennifer Wang, Christos J. Petropoulos, Alex Luedtke, Yiwen Lu, Chenchen Yu, Michal Juraska, Nima S. Hejazi, Daniel N. Wolfe, Jerald Sadoff, Glenda E. Gray, Beatriz Grinsztejn, Paul A. Goepfert, Linda-Gail Bekker, Aditya H. Gaur, Valdilea G. Veloso, April K. Randhawa, Michele P. Andrasik, Jenny Hendriks, Carla Truyers, An Vandebosch, Frank Struyf, Hanneke Schuitemaker, Macaya Douoguih, James G. Kublin, Lawrence Corey, Kathleen M. Neuzil, Dean Follmann, Richard A. Koup, Ruben O. Donis, Peter B. Gilbert, On behalf of the Immune Assays Team, the Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team, the United States Government (USG)/CoVPN Biostatistics Team
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Assessment of immune correlates of severe COVID-19 has been hampered by the low numbers of severe cases in COVID-19 vaccine efficacy (VE) trials. We assess neutralizing and binding antibody levels at 4 weeks post-Ad26.COV2.S vaccination as c
Externí odkaz:
https://doaj.org/article/e3fbd928bb5b421b95c9d27047187105
Autor:
Joshua S. Woodworth, Vanessa Contreras, Dennis Christensen, Thibaut Naninck, Nidhal Kahlaoui, Anne-Sophie Gallouët, Sébastien Langlois, Emma Burban, Candie Joly, Wesley Gros, Nathalie Dereuddre-Bosquet, Julie Morin, Ming Liu Olsen, Ida Rosenkrands, Ann-Kathrin Stein, Grith Krøyer Wood, Frank Follmann, Thomas Lindenstrøm, Tu Hu, Roger Le Grand, Gabriel Kristian Pedersen, Rasmus Mortensen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Development of new vaccines tailored for difficult-to-target diseases is hampered by a lack of diverse adjuvants for human use, and none of the currently available adjuvants induce Th17 cells. Here, we develop a liposomal adjuvant, CAF®10b,
Externí odkaz:
https://doaj.org/article/247707a325064a6ea6e1237d4d196721
Autor:
S. Blödt, S. Erstling, M. Becker, G. Carl, M. Follmann, S. Frenz, C. Holmberg, T. Langer, A. Pachanov, D. Pieper, M. Nothacker
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background To investigate awareness, use, and perceptions of the patient guidelines (PGs) of the German Guideline Program in Oncology (GGPO) and to explore general preferences regarding cancer information among patients and healthcare provid
Externí odkaz:
https://doaj.org/article/1b2c8d29858641ecb0ef32b67af5ea25
Autor:
Bo Zhang, Youyi Fong, Jonathan Fintzi, Eric Chu, Holly E. Janes, Avi Kenny, Marco Carone, David Benkeser, Lars W. P. van der Laan, Weiping Deng, Honghong Zhou, Xiaowei Wang, Yiwen Lu, Chenchen Yu, Bhavesh Borate, Haiyan Chen, Isabel Reeder, Lindsay N. Carpp, Christopher R. Houchens, Karen Martins, Lakshmi Jayashankar, Chuong Huynh, Carl J. Fichtenbaum, Spyros Kalams, Cynthia L. Gay, Michele P. Andrasik, James G. Kublin, Lawrence Corey, Kathleen M. Neuzil, Frances Priddy, Rituparna Das, Bethany Girard, Hana M. El Sahly, Lindsey R. Baden, Thomas Jones, Ruben O. Donis, Richard A. Koup, Peter B. Gilbert, Dean Follmann, On behalf of the United States Government (USG) COVID-19 Immune Assays Team, Moderna, Inc. Team, Coronavirus Vaccine Prevention Network (CoVPN)/Coronavirus Efficacy (COVE) Team, USG/CoVPN Biostatistics Team
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract In the phase 3 Coronavirus Efficacy (COVE) trial (NCT04470427), post-dose two Ancestral Spike-specific binding (bAb) and neutralizing (nAb) antibodies were shown to be correlates of risk (CoR) and of protection against Ancestral-lineage COVI
Externí odkaz:
https://doaj.org/article/3b5ac665acef48f6bef0aa0502ebe57b
Autor:
Nadja Könsgen, Julia Hauprich, Sarah Wahlen, Irma Hellbrecht, Monika Becker, Stefanie Bühn, Nora Meyer, Susanne Blödt, Günther Carl, Markus Follmann, Stefanie Frenz, Thomas Langer, Monika Nothacker, Corinna Schaefer, Dawid Pieper, Jessica Breuing
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Oncological patients have high information needs that are often unmet. Patient versions of oncological clinical practice guidelines (PVG) translate clinical practice guidelines into laypersons’ language and might help to address
Externí odkaz:
https://doaj.org/article/a97fa8143ec140f189a1b02aef33af3d
Autor:
Lindsey R. Baden, Hana M. El Sahly, Brandon Essink, Dean Follmann, Gregory Hachigian, Cynthia Strout, J. Scott Overcash, Susanne Doblecki-Lewis, Jennifer A. Whitaker, Evan J. Anderson, Kathleen Neuzil, Lawrence Corey, Frances Priddy, Joanne E. Tomassini, Mollie Brown, Bethany Girard, Dina Stolman, Veronica Urdaneta, Xiaowei Wang, Weiping Deng, Honghong Zhou, Avika Dixit, Rituparna Das, Jacqueline M. Miller, the COVE Trial Consortium
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Primary vaccination with mRNA-1273 (100-µg) was safe and efficacious at preventing coronavirus disease 2019 (COVID-19) in the previously reported, blinded Part A of the phase 3 Coronavirus Efficacy (COVE; NCT04470427) trial in adults (≥18
Externí odkaz:
https://doaj.org/article/b9044673d7cd478088d5513d33602744
Autor:
Guilherme Bergeijer da Rosa, Diego Nicolau Follmann, Alessandro Alessandro Dal’Col Lúcio, Rodrigo Josemar Seminoti Jacques, Valéria Ortaça Portela, Volmir Sergio Marchioro
Publikováno v:
Acta Scientiarum: Agronomy, Vol 47, Iss 1 (2024)
Soil organisms are vital for soil quality and can indicate environmental conditions. This study aimed to understand the diversity of soil fauna and its connection to plant residue decomposition and maize grain yield across various locations and crop
Externí odkaz:
https://doaj.org/article/31f532a760d34e59ada47bd1b697b093
Autor:
Kunczik, Janosch, Hubbermann, Kerstin, Mösch, Lucas, Follmann, Andreas, Czaplik, Michael, Pereira, Carina Barbosa
Breathing is one of the most important body functions because it provides it with oxygen, which is vital for energy production. In addition, the removal of carbon dioxide actively regulates the acid-base level, which is essential for the physiologica
Externí odkaz:
http://arxiv.org/abs/2210.08799
Autor:
Fay Michael P., Follmann Dean A.
Publikováno v:
Journal of Causal Inference, Vol 12, Iss 1, Pp 43-50 (2024)
We review standard mediation assumptions as they apply to identifying antibody effects in a randomized vaccine trial and propose new study designs to allow the identification of an estimand that was previously unidentifiable. For these mediation anal
Externí odkaz:
https://doaj.org/article/46f4bd7e66a2432298f097ca476d66cb