Zobrazeno 1 - 10
of 868
pro vyhledávání: '"A. F. Ziegler"'
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011350 (2023)
In order to recover from infection, organisms must balance robust immune responses to pathogens with the tolerance of immune-mediated pathology. This balance is particularly critical within the central nervous system, whose complex architecture, esse
Externí odkaz:
https://doaj.org/article/83fe8b4be7f84885851baeb38173ee63
Autor:
Tadamichi Kasuya, Shigeru Tanaka, Jun Tamura, Keishi Etori, Jumpei Shoda, Koto Hattori, Yusuke Endo, Masayuki Kitajima, Takahiro Kageyama, Taro Iwamoto, Masaya Yokota, Arifumi Iwata, Akira Suto, Kotaro Suzuki, Harumi Suzuki, Steven F. Ziegler, Hiroshi Nakajima
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Epithelial cells control a variety of immune cells by secreting cytokines to maintain tissue homeostasis on mucosal surfaces. Regulatory T (Treg) cells are essential for immune homeostasis and for preventing tissue inflammation; however, the
Externí odkaz:
https://doaj.org/article/e0fac211478b4b9593b3587845ada559
Autor:
Elizabeth R. Vanderwall, Kaitlyn A. Barrow, Lucille M. Rich, David F. Read, Cole Trapnell, Oghenemega Okoloko, Steven F. Ziegler, Teal S. Hallstrand, Maria P. White, Jason S. Debley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Common alphacoronaviruses and human rhinoviruses (HRV) induce type I and III interferon (IFN) responses important to limiting viral replication in the airway epithelium. In contrast, highly pathogenic betacoronaviruses including SARS-CoV-2 m
Externí odkaz:
https://doaj.org/article/819ee770cae44309ba0d6e569bdb3358
Autor:
Ivan J. Cautain, Kim S. Last, David McKee, Bodil A. Bluhm, Paul E. Renaud, Amanda F. Ziegler, Bhavani E. Narayanaswamy
Publikováno v:
Frontiers in Marine Science, Vol 9 (2022)
On Arctic shelves, where primary production occurs in both the pelagic and sympagic (ice-associated) habitats, sympagic organic material (OM) can constitute a disproportionate fraction of benthic diets due to higher sinking rates and lower grazing pr
Externí odkaz:
https://doaj.org/article/482b27b8db95467983ec9cb685161819
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104998- (2022)
Summary: Foxp3+ regulatory T cells (Tregs) are critical mediators of peripheral tolerance and immune homeostasis and exert tissue-specific functions. In many nonlymphoid tissues, Tregs show enriched expression of the IL-33 receptor ST2. Through compr
Externí odkaz:
https://doaj.org/article/60bbf8efbcb94546bc29ddff72c0232c
Autor:
Jörn F. Ziegler, Chotima Böttcher, Marilena Letizia, Cansu Yerinde, Hao Wu, Inka Freise, Yasmina Rodriguez-Sillke, Ani K. Stoyanova, Martin E. Kreis, Patrick Asbach, Desiree Kunkel, Josef Priller, Ioannis Anagnostopoulos, Anja A. Kühl, Konstanze Miehle, Michael Stumvoll, Florian Tran, Broder Fredrich, Michael Forster, Andre Franke, Christian Bojarski, Rainer Glauben, Britt-Sabina Löscher, Britta Siegmund, Carl Weidinger
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The adipokine leptin modulates intestinal inflammation in mice. Here the authors describe a patient with inflammatory bowel disease and lipodystrophy, providing evidence that leptin aggravates intestinal inflammation with proinflammatory effects on l
Externí odkaz:
https://doaj.org/article/930d669ed7b944499b66502ad66aa5e6
Publikováno v:
The Journal of Immunology. 210:888-894
The thymus is an intricate organ consisting of a diverse population of thymic epithelial cells (TECs). Cortical and medullary TECs and their subpopulations have distinct roles in coordinating the development and selection of functionally competent an
Autor:
Taha Al‐Shaikhly, Ryan C. Murphy, Ying Lai, Charles W. Frevert, Jason S. Debley, Steven F. Ziegler, Kit Wong, Guiquan Jia, Cecile T. J. Holweg, Michael C. Peters, Teal S. Hallstrand
Publikováno v:
Respirology. 28:491-494
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Helminths remain one of the most prolific pathogens in the world. Following infection helminths interact with various epithelial cell surfaces, including skin, lung, and gut. Recent works have shown that epithelial cells produce a series of cytokines
Externí odkaz:
https://doaj.org/article/fdfd86272793436a8308568f7dedb58b
Autor:
Stephanie M. Williams, John F. Ziegler
Publikováno v:
Ear, Nose & Throat Journal. 101:6S-15S
Aspiring physicians face a large amount of information that must be learned and retrieved in real time. The skills that helped medical students reach residency may not be the enough to succeed as a physician. For example, like many students, cramming