Zobrazeno 1 - 10
of 31
pro vyhledávání: '"A. F. Vaisburg"'
Autor:
Theresa P. Yan, Silvana Leit, Claire Bonfils, Tammy C. Mallais, Zuomei Li, Marielle Fournel, Jianhong Liu, Jubrail Rahil, Aihua Lu, and Arkadii F. Vaisburg, Sylvain Lefebvre, Isabelle Paquin, Marie-Claude Trachy-Bourget, Oscar Moradei, Jeffrey M. Besterman, James Wang, Sylvie Frechette, Pierre Tessier
Publikováno v:
Journal of Medicinal Chemistry. 50:5543-5546
Significant effort is being made to understand the role of HDAC isotypes in human cancer and to develop antitumor agents with better therapeutic windows. A part of this endeavor was the exploration of the 14 A internal cavity adjacent to the enzyme c
Autor:
A. F. Vaisburg, Heinz Falk
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 126:361-364
In contrast to hitherto published data, phenanthro[1,10,9,8,o,p,q,r,a]perylene-7,14-dione, the fundamental chromophoric system of hypericin type compounds, exhibits an absorption with a long wavelength band at 423 nm in aprotic solvents like dimethyl
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 126:773-781
The acid promoted decomposition of 2-(10-diazo-10H-anthracen-9-ylidene)-malonodinitrile in the presence of water, methanol, ethanol, acetic and propionic acid, ethyl thioglycolate,p-thiocresole, and acetyl acetone yielding 9,10-disubstituted 9,10-dih
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 126:783-788
The reaction of 2-(10-diazo-10H-anthracen-9-ylidene)-malonodinitrile (1) with the cryptohydride system formic acid - triethylamine was studied. The reaction product turned out to be anthracen-9-yl-acetonitrile (2a) instead of the expected 10-dicyanom
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 126:993-1000
A method for the preparation ofbis-ω-appended hypericin derivatives bearingn-octyl,n-hexadecyl, and 2-(2-(2-hydroxyethoxy)-ethoxy)-ethoxymethyl substituents was developed. The key step — the synthesis of appropriately ω-substituted emodin derivat
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 125:1121-1127
The chemical nature of 10-dicyanomethylene-9-anthrone hydrazone was examined. It was shown that this compound bearing the conjugated ylidenemalononitrile fragment and hydrazonic moiety did not undergo transformations characteristic of ylidenemalononi
Autor:
A. F. Vaisburg, A. P. Tarasov, B. V. Tyaglov, E. V. Degterev, V. G. Degtyar, I. I. Malakhova, V. D. Krasikov, V. M. Krylov
Publikováno v:
Pharmaceutical Chemistry Journal. 28:274-277
Publikováno v:
ChemInform. 23
This review is devoted to the latest achievements in the chemistry of vicinal heteroaromatic hydroxy, mercapto and hydroseleno aldimines. The synthesis, structure and reactivity of the above compounds are presented and discussed.
Autor:
Heinz Falk, A. F. Vaisburg
Publikováno v:
ChemInform. 25
A novel reaction of 11,11,12,12-tetracyanoanthraquinodimethane — its transformation into 10-dicyanomethylene-anthrone hydrazone by reaction with hydrazine — is reported. This hydrazone seems to be a convenient starting material in the synthesis o
Autor:
A. F. Vaisburg, Heinz Falk
Publikováno v:
ChemInform. 26
In contrast to hitherto published data, phenanthro[1,10,9,8,o,p,q,r,a]perylene-7,14-dione, the fundamental chromophoric system of hypericin type compounds, exhibits an absorption with a long wavelength band at 423 nm in aprotic solvents like dimethyl