Zobrazeno 1 - 10
of 506
pro vyhledávání: '"A. F. Page"'
Autor:
Florence M. Chardon, Troy A. McDiarmid, Nicholas F. Page, Riza M. Daza, Beth K. Martin, Silvia Domcke, Samuel G. Regalado, Jean-Benoît Lalanne, Diego Calderon, Xiaoyi Li, Lea M. Starita, Stephan J. Sanders, Nadav Ahituv, Jay Shendure
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract CRISPR-based gene activation (CRISPRa) is a strategy for upregulating gene expression by targeting promoters or enhancers in a tissue/cell-type specific manner. Here, we describe an experimental framework that combines highly multiplexed per
Externí odkaz:
https://doaj.org/article/9bd7fc937a4c4d249a6334bbcbf59eb9
Autor:
Elizabeth T. Evans, Emily F. Page, Alex Seok Choi, Zainab Shonibare, Andrea G. Kahn, Rebecca C. Arend, Karthikeyan Mythreye
Publikováno v:
Cancer Medicine, Vol 13, Iss 17, Pp n/a-n/a (2024)
Abstract Objective The TGF‐β superfamily member activin, a dimer of the gene products of INHBA and/or INHBB, has been implicated in immune cell maturation and recruitment, but its immune impact within epithelial ovarian cancer (EOC) is not well ch
Externí odkaz:
https://doaj.org/article/9a6ef7941d9d4424a939ec5da6563127
Autor:
Siavash Fazel Darbandi, Joon-Yong An, Kenneth Lim, Nicholas F. Page, Lindsay Liang, David M. Young, Athena R. Ypsilanti, Matthew W. State, Alex S. Nord, Stephan J. Sanders, John L.R. Rubenstein
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114329- (2024)
Summary: Many autism spectrum disorder (ASD)-associated genes act as transcriptional regulators (TRs). Chromatin immunoprecipitation sequencing (ChIP-seq) was used to identify the regulatory targets of ARID1B, BCL11A, FOXP1, TBR1, and TCF7L2, ASD-ass
Externí odkaz:
https://doaj.org/article/96b97b7930204f6ea8932076d915ef71
Autor:
Iva Salamon, Yongkyu Park, Terezija Miškić, Janja Kopić, Paul Matteson, Nicholas F. Page, Alfonso Roque, Geoffrey W. McAuliffe, John Favate, Marta Garcia-Forn, Premal Shah, Miloš Judaš, James H. Millonig, Ivica Kostović, Silvia De Rubeis, Ronald P. Hart, Željka Krsnik, Mladen-Roko Rasin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Abnormalities in neocortical and synaptic development are linked to neurodevelopmental disorders. However, the molecular and cellular mechanisms governing initial synapse formation in the prenatal neocortex remain poorly understood. Using po
Externí odkaz:
https://doaj.org/article/0ecc88f4fb9b43139559f4cbaf05e541
Autor:
Fiona L. Macphee, Stephanie K. Brewer, Margaret H. Sibley, Paulo Graziano, Joseph S. Raiker, Stefany J. Coxe, Pablo Martin, Shauntal J. Van Dreel, Mercedes Ortiz Rodriguez, Aaron R. Lyon, Timothy F. Page
Publikováno v:
BMC Psychology, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Background Youth with ADHD are at risk of academic impairments, dropping out of high school, and dysfunction in young adulthood. Interventions delivered early in high school could prevent these harmful outcomes, yet few high school students
Externí odkaz:
https://doaj.org/article/3474705f032d47ef906127315c617fc8
Autor:
Tatiana Popovitchenko, Yongkyu Park, Nicholas F. Page, Xiaobing Luo, Zeljka Krsnik, Yuan Liu, Iva Salamon, Jessica D. Stephenson, Matthew L. Kraushar, Nicole L. Volk, Sejal M. Patel, H. R. Sagara Wijeratne, Diana Li, Kandarp S. Suthar, Aaron Wach, Miao Sun, Sebastian J. Arnold, Wado Akamatsu, Hideyuki Okano, Luc Paillard, Huaye Zhang, Steven Buyske, Ivica Kostovic, Silvia De Rubeis, Ronald P. Hart, Mladen-Roko Rasin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Translational regulation of isoforms in the developing nervous system is not well understood. Here, the authors report translational de-repression of RNA binding protein isoforms at their 5′UTRs in the neocortex and show the neurodevelopmental risk
Externí odkaz:
https://doaj.org/article/26ec0393d8414ff985171a47ea4a1728
Publikováno v:
Population Health Management. 26:83-91
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c1931de76f238f6f8534e7e0be0a8c3
https://doi.org/10.1089/pop.2022.0258
https://doi.org/10.1089/pop.2022.0258
Publikováno v:
Population Health Management. 25:480-486
Emergency department (ED) visits for drug overdoses increased nationally during COVID-19 despite declines in all-cause ED visits. The study purpose was to compare characteristics of ED visits for opioid and stimulant overdoses before and during COVID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff796a7eb7d9d080aedfbf0c560eb30
https://doi.org/10.1089/pop.2021.0369
https://doi.org/10.1089/pop.2021.0369
Autor:
Jennifer Piscitello, Amy R. Altszuler, Jessica Robb Mazzant, Dara E. Babinski, Elizabeth M. Gnagy, Timothy F. Page, Brooke S. G. Molina, William E. Pelham
Publikováno v:
Research on Child and Adolescent Psychopathology. 50:1275-1288
Childhood attention-deficit/hyperactivity disorder (ADHD) is associated with substantial burden to caregiver quality of life (QoL). However, a paucity of work has focused on quantifying QoL among caregivers of adolescents with a history of ADHD. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456be8f05905db3f1576ac4de913bf7a
https://doi.org/10.1007/s10802-022-00935-z
https://doi.org/10.1007/s10802-022-00935-z
Publikováno v:
Population Health Management. 25:109-118
The integration of medical schools and clinical partners is effectively established through the formation of academic medical centers (AMCs). The tripartite mission of AMCs emphasizes the importance of providing critical clinical services, medical in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8363977710b8a756e56e8ca1904cc8
https://doi.org/10.1089/pop.2021.0097
https://doi.org/10.1089/pop.2021.0097