Zobrazeno 1 - 10
of 47
pro vyhledávání: '"A. F. Paes Leme"'
Autor:
Natália S. Wassano, Gabriela B. da Silva, Artur H. Reis, Jaqueline A. Gerhardt, Everton P. Antoniel, Daniel Akiyama, Caroline P. Rezende, Leandro X. Neves, Elton J. R. Vasconcelos, Fernanda L. de Figueiredo, Fausto Almeida, Patrícia A. de Castro, Camila F. Pinzan, Gustavo H. Goldman, Adriana F. Paes Leme, Taicia P. Fill, Nilmar S. Moretti, André Damasio
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Aspergillus fumigatus represents a public health problem due to the high mortality rate in immunosuppressed patients and the emergence of antifungal-resistant isolates. Protein acetylation is a crucial post-translational modification that co
Externí odkaz:
https://doaj.org/article/e94c592492c34094b6c73563cbaa8160
Autor:
Ariane F. Busso-Lopes, Leandro X. Neves, Guilherme A. Câmara, Daniela C. Granato, Marco Antônio M. Pretti, Henry Heberle, Fábio M. S. Patroni, Jamile Sá, Sami Yokoo, César Rivera, Romênia R. Domingues, Ana Gabriela C. Normando, Tatiane De Rossi, Barbara P. Mello, Nayane A. L. Galdino, Bianca A. Pauletti, Pammela A. Lacerda, André Afonso N. Rodrigues, André Luis M. Casarim, Reydson A. de Lima-Souza, Ingrid I. Damas, Fernanda V. Mariano, Kenneth J. Gollob, Tiago S. Medina, Nilva K. Cervigne, Ana Carolina Prado-Ribeiro, Thaís Bianca Brandão, Luisa L. Villa, Miyuki Uno, Mariana Boroni, Luiz Paulo Kowalski, Wilfredo Alejandro González-Arriagada, Adriana F. Paes Leme
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-24 (2022)
The biological understanding of poor prognosis associated with lymph node metastasis in head and neck cancer (HNC) remains crucial. Here, a proteomic characterisation of 140 multisite samples from a 59-HNC patient cohort and machine learning reveals
Externí odkaz:
https://doaj.org/article/4ccd9c9167ab4e6c9dea6fe4abdd58c2
Autor:
Helder V. Ribeiro-Filho, Lais D. Coimbra, Alexandre Cassago, Rebeca P. F. Rocha, João Victor da Silva Guerra, Rafael de Felicio, Carolina Moretto Carnieli, Luiza Leme, Antonio Cláudio Padilha, Adriana F. Paes Leme, Daniela B. B. Trivella, Rodrigo Villares Portugal, Paulo Sérgio Lopes-de-Oliveira, Rafael Elias Marques
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Mayaro virus (MAYV) is an emerging arbovirus in Central and South America that is transmitted by mosquitoes and causes arthritogenic disease. Here, the authors present the 4.4 Å resolution cryo-EM structure of MAYV and describe specific features of
Externí odkaz:
https://doaj.org/article/ccf9e12fb93247bf974fca9104dc9dea
Autor:
Giselle Pidde, Milton Y. Nishiyama, Ursula Castro de Oliveira, Isadora M. Villas-Boas, Adriana F. Paes-Leme, Inácio L. Junqueira-de-Azevedo, Rafael Marques-Porto, Carla C. Squaiella-Baptistão, Denise V. Tambourgi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The joint disease called pararamosis is an occupational disease caused by accidental contact with bristles of the caterpillar Premolis semirufa. The chronic inflammatory process narrows the joint space and causes alterations in bone structur
Externí odkaz:
https://doaj.org/article/736b93df965e40d5943af7832e4cf9a0
Autor:
Liudmila Lobastova, Marcus Lettau, Felix Babatz, Thais Dolzany de Oliveira, Phuong-Hien Nguyen, Bianca Alves Pauletti, Astrid C. Schauss, Horst Dürkop, Ottmar Janssen, Adriana F. Paes Leme, Michael Hallek, Hinrich P. Hansen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
CD30, a member of the TNF receptor superfamily, is selectively expressed on a subset of activated lymphocytes and on malignant cells of certain lymphomas, such as classical Hodgkin Lymphoma (cHL), where it activates critical bystander cells in the tu
Externí odkaz:
https://doaj.org/article/ee4ad5abc83c476f806f4f05d2d13b45
Autor:
Larissa Tinô de Carvalho-Silva, Ana Gabriela C. Normando, Jamile de Oliveira Sá, Erison Santana dos Santos, Tatiane De Rossi, Ariane Fidelis Busso-Lopes, Ana Karina de Oliveira, Adriana F. Paes Leme
Publikováno v:
Biochemical Society Transactions. 51:771-781
Cancer is a significant cause of death, precluding increasing life expectancy worldwide. That is a multifactorial disease initiated by intrinsic or extrinsic factors that induce cell differentiation into cancer cells. However, cancer development, pro
Autor:
Rute A.P. e Costa, Daniela C. Granato, Luciana D. Trino, Sami Yokoo, Carolina M. Carnielli, Rebeca Kawahara, Romênia R. Domingues, Bianca Alves Pauletti, Leandro Xavier Neves, Aline G. Santana, Joao A. Paulo, Annelize Z.B. Aragão, Fernanda Aparecida Heleno Batista, Ana Carolina Migliorini Figueira, Francisco R.M. Laurindo, Denise Fernandes, Hinrich P. Hansen, Fabio Squina, Steven P. Gygi, Adriana F. Paes Leme
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101735- (2020)
The activity of Thioredoxin-1 (Trx-1) is adjusted by the balance of its monomeric, active and its dimeric, inactive state. The regulation of this balance is not completely understood. We have previously shown that the cytoplasmic domain of the transm
Externí odkaz:
https://doaj.org/article/01655612ffe74f118f13212f27c6770e
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cancer cells generally recruit and influence non-malignant immune cells to support the tumor growth. Classical Hodgkin lymphoma (cHL) is a good example because the affected lymphoid tissue contains only a few malignant Hodgkin and Reed-Sternberg (H-R
Externí odkaz:
https://doaj.org/article/8a9f9fc13cdf4c67b8fa1a8f485b3ab7
Autor:
Alejandro F. Prado, Laena Pernomian, Aline Azevedo, Rute A.P. Costa, Elen Rizzi, Junia Ramos, Adriana F. Paes Leme, Lusiane M. Bendhack, Jose E. Tanus-Santos, Raquel F. Gerlach
Publikováno v:
Redox Biology, Vol 18, Iss , Pp 181-190 (2018)
Increased reactive oxygen species (ROS) formation may enhance matrix metalloproteinase (MMP)-2 activity and promote cardiovascular dysfunction. We show for the first time that MMP-2 is upstream of increased ROS formation and activates signaling mecha
Externí odkaz:
https://doaj.org/article/fe0deb369da74aa592c89176fb3efd02
Autor:
Bianca A. Pauletti, Daniela C. Granato, Carolina M. Carnielli, Guilherme A. Câmara, Ana Gabriela C. Normando, Guilherme P. Telles, Adriana F. Paes Leme
Publikováno v:
Journal of Proteome Research. 22:539-545
The selection of a suitable proteotypic peptide remains a challenge for designing a targeted quantitative proteomics assay. Although the criteria are well-established in the literature, the selection of these peptides is often performed in a subjecti