Zobrazeno 1 - 10
of 393
pro vyhledávání: '"A. F. Lobuglio"'
Autor:
Christos Vaklavas, Brian S. Roberts, Katherine E. Varley, Nancy U. Lin, Minetta C. Liu, Hope S. Rugo, Shannon Puhalla, Rita Nanda, Anna Maria Storniolo, Lisa A. Carey, Mansoor N. Saleh, Yufeng Li, Jennifer F. Delossantos, William E. Grizzle, Albert F. LoBuglio, Richard M. Myers, Andres Forero-Torres, on behalf of the Translational Breast Cancer Research Consortium (TBCRC)
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-15 (2020)
Abstract Background In preclinical studies, the expression of vascular endothelial growth factor (VEGF) in hormone receptor-positive breast cancer is associated with estrogen-independent tumor growth and resistance to endocrine therapies. This study
Externí odkaz:
https://doaj.org/article/5584ed790988432a9d02c709cacd449f
Autor:
Eddy S. Yang, Susan E. Nozell, Albert F. LoBuglio, Rachel Schiff, C. Kent Osborne, Francisco J. Esteva, Andres Forero, Ling Zeng, Tiffiny S. Cooper, Rajani Rajbhandari, Zhuo Zhang, Monica E. Wielgos
Supplemental Methods and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c5a8b57cc45d1d222f8d418e134855
https://doi.org/10.1158/1535-7163.22505158
https://doi.org/10.1158/1535-7163.22505158
Autor:
Katherine E. Varley, Albert F. LoBuglio, Richard M. Myers, Donald J. Buchsbaum, Christos Vaklavas, Todd C. Burwell, Erinn Downs-Kelly, Natalie D. Merz, Katherine L. Updike, William E. Grizzle, Dongquan Chen, Yufeng Li, Andres Forero
This file contains: Supplementary Methods for Tissue Processing, RNA-seq, RNA-seq analysis, and Immunohistochemistry. Supplementary Figure 1: Overlap between clusters identified in our data and TNBC subtypes described in previous studies. Supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc0ebc556aafb5e0bffd7f3a5ecaae1
https://doi.org/10.1158/2326-6066.22537210.v1
https://doi.org/10.1158/2326-6066.22537210.v1
Autor:
Donald J. Buchsbaum, Yonghe Li, Albert F. LoBuglio, Andres Forero-Torres, Michael Conner, William E. Grizzle, Bertha Hidalgo, Brandon J. Metge, Rajeev S. Samant, Wenyan Lu, Laura Aristizabal, Rebecca C. Arend, Angelina I. Londoño-Joshi
PDF file - 96KB, Supplementary Figure S4. Wnt/beta-catenin signaling proteins in LRP6 KD cells. Western blot for expression of Wnt/beta-catenin signaling proteins in adherent 2LMP shRNA LRP6 knockdown cells compared to shRNA control cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62391a1fdd262bc11149ca51aa330ba1
https://doi.org/10.1158/1535-7163.22501198.v1
https://doi.org/10.1158/1535-7163.22501198.v1
Autor:
Donald J. Buchsbaum, Yonghe Li, Albert F. LoBuglio, Andres Forero-Torres, Michael Conner, William E. Grizzle, Bertha Hidalgo, Brandon J. Metge, Rajeev S. Samant, Wenyan Lu, Laura Aristizabal, Rebecca C. Arend, Angelina I. Londoño-Joshi
PDF file - 59KB, Supplementary Figure S5. In vivo toxicity study. Athymic nude mice were treated with niclosamide (20 mg/kg), TRA-8 (200 ng) or the combination for two weeks. Mice were weighed twice a week for two weeks.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfe308ba5fee13ae447f39f024cdf47
https://doi.org/10.1158/1535-7163.22501195.v1
https://doi.org/10.1158/1535-7163.22501195.v1
Autor:
Katherine E. Varley, Albert F. LoBuglio, Richard M. Myers, Donald J. Buchsbaum, Christos Vaklavas, Todd C. Burwell, Erinn Downs-Kelly, Natalie D. Merz, Katherine L. Updike, William E. Grizzle, Dongquan Chen, Yufeng Li, Andres Forero
Triple-negative breast cancer (TNBC) is a subtype with heterogeneous patient outcomes. Approximately 40% of patients experience rapid relapse, while the remaining patients have long-term disease-free survival. To determine if there are molecular diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3047575fc84af0f45c1779f997f467
https://doi.org/10.1158/2326-6066.c.6548350.v1
https://doi.org/10.1158/2326-6066.c.6548350.v1
Autor:
Donald J. Buchsbaum, Yonghe Li, Albert F. LoBuglio, Andres Forero-Torres, Michael Conner, William E. Grizzle, Bertha Hidalgo, Brandon J. Metge, Rajeev S. Samant, Wenyan Lu, Laura Aristizabal, Rebecca C. Arend, Angelina I. Londoño-Joshi
Basal-like breast cancers (BLBC) are poorly differentiated and display aggressive clinical behavior. These tumors become resistant to cytotoxic agents, and tumor relapse has been attributed to the presence of cancer stem cells (CSC). One of the pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9fc754454330c6f71df77c99c1a53c4
https://doi.org/10.1158/1535-7163.c.6536704.v1
https://doi.org/10.1158/1535-7163.c.6536704.v1
Autor:
Donald J. Buchsbaum, Yonghe Li, Albert F. LoBuglio, Andres Forero-Torres, Michael Conner, William E. Grizzle, Bertha Hidalgo, Brandon J. Metge, Rajeev S. Samant, Wenyan Lu, Laura Aristizabal, Rebecca C. Arend, Angelina I. Londoño-Joshi
PDF file - 128KB, Supplementary Figure S1. Sensitivity of MF10A mammary epithelial cells to niclosamide and TRA-8 mediated cytotoxicity. (A) Attached MCF10A cell line was treated for 48 hours with niclosamide (0.08, 0.1, 0.25 and 0.5 microM) and anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d0e09d6baeec9367ab372c9916dde0
https://doi.org/10.1158/1535-7163.22501207
https://doi.org/10.1158/1535-7163.22501207
Autor:
Donald J. Buchsbaum, Yonghe Li, Albert F. LoBuglio, Andres Forero-Torres, Michael Conner, William E. Grizzle, Bertha Hidalgo, Brandon J. Metge, Rajeev S. Samant, Wenyan Lu, Laura Aristizabal, Rebecca C. Arend, Angelina I. Londoño-Joshi
PDF file - 89KB, Supplementary Table S1. Sensitivity of BLBC cell lines to niclosamide mediated cytotoxicity. SUM159, HCC1187, HCC1143 and 2LMP BLBC NAAE and adherent cell lines were treated with niclosamide for 48 hours and analyzed for viability us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a248301c09377c4d379a741b0c1f11fa
https://doi.org/10.1158/1535-7163.22501192
https://doi.org/10.1158/1535-7163.22501192
Autor:
Eddy S. Yang, Susan E. Nozell, Albert F. LoBuglio, Rachel Schiff, C. Kent Osborne, Francisco J. Esteva, Andres Forero, Ling Zeng, Tiffiny S. Cooper, Rajani Rajbhandari, Zhuo Zhang, Monica E. Wielgos
SFigure1: HER2+ breast cancer cells are sensitive to nirparib SFigure2: HER2+ breast cancer microtumors are sensitive to ABT-888 SFigure3: (A) ABT-888 reduces PAR levels in HER2+ xenograft models. (B) ABT-888 did not cause weight loss in mice SFigure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304cc460640481e9f8fa3bf07cd6c7b4
https://doi.org/10.1158/1535-7163.22505161.v1
https://doi.org/10.1158/1535-7163.22505161.v1