Zobrazeno 1 - 10
of 608
pro vyhledávání: '"A. F. Ferris"'
Autor:
Bradley Colarusso, Richard Ortiz, Julian Yeboah, Arnold Chang, Megha Gupta, Praveen Kulkarni, Craig F. Ferris
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract The strongest genetic risk factor for Alzheimer’s disease (AD) is the ε4 allele of apolipoprotein E (ApoE ε4). A high fat diet also adds to the risk of dementia and AD. In addition, there are sex differences as women carriers have a high
Externí odkaz:
https://doaj.org/article/84b841c02c4246fd93591f8ffbdf092a
Autor:
Lila Harris-Blum, Zachary Smith, Richard J. Ortiz, Deepti Athreya, Arnold Chang, Praveen P. Kulkarni, Craig F. Ferris
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract LSD is a hallucinogen with complex neurobiological and behavioral effects. Underlying these effects are changes in brain neuroplasticity. This is the first study to follow the developmental changes in brain structure and function following L
Externí odkaz:
https://doaj.org/article/e5e2dc4fc1124717a84df8062847a3b3
Autor:
Shreyas Balaji, Taylor J. Woodward, Emily Richter, Arnold Chang, Richard Otiz, Praveen P. Kulkarni, Kaashyap Balaji, Heather B. Bradshaw, Craig F. Ferris
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
The present studies were undertaken to understand the effects of the commonly used nutraceutical PEA on brain function and lipid chemistry. These studies using MRI and broad-scale lipidomics are without precedent in animal or human research. During t
Externí odkaz:
https://doaj.org/article/484aa0118d7f4f92940aac8659ec8a1e
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundThere are increasing reports of the misuse of prescription psychostimulants for cognitive enhancement together with recreational cannabis. This raises a concern that chronic use of cannabis high in Δ9-THC may alter the sensitivity to amphe
Externí odkaz:
https://doaj.org/article/f727d7ba3aa846f99d4bbeb35c235fa5
Autor:
Bethany F Ferris, Suganthi Balasubramanian, Anuradha Rajamanickam, Saravanan Munisankar, Bindu Dasan, Pradeep A Menon, P'ng Loke, Subash Babu, Goylette F Chami
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0305819 (2024)
BackgroundIn the first year of roll-out, vaccination for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) prevented almost 20 million deaths from coronavirus disease 2019 (COVID-19). Yet, little is known about the factors influencing acce
Externí odkaz:
https://doaj.org/article/e13f6a09e0094008ac8545598fc79edf
Autor:
Preeti K. Sathe, Gargi R. Ramdasi, Kaylie Giammatteo, Harvens Beauzile, Shuyue Wang, Heng Zhang, Praveen Kulkarni, Raymond G. Booth, Craig F. Ferris
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract A novel serotonin ligand (−)‐MBP was developed for the treatment of schizophrenia that has 5‐HT2A/2B antagonist activity together with 5‐HT2C agonist activity. The multi‐functional activity of this novel drug candidate was characte
Externí odkaz:
https://doaj.org/article/111258ebd5264bafa71dab06a81a5a07
Autor:
Monika Sharma, Ivana Barravecchia, Brian Magnuson, Sarah F. Ferris, April Apfelbaum, Nneka E. Mbah, Jeanette Cruz, Varunkumar Krishnamoorthy, Robert Teis, McKenzie Kauss, Carl Koschmann, Costas A. Lyssiotis, Mats Ljungman, Stefanie Galban
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 44, Iss , Pp 100931- (2023)
Therapeutic resistance remains a major obstacle to preventing progression of H3K27M-altered Diffuse Midline Glioma (DMG). Resistance is driven in part by ALDH-positive cancer stem cells (CSC), with high ALDH1A3 expression observed in H3K27M-mutant DM
Externí odkaz:
https://doaj.org/article/fff441e5d0a2496d9954b19d9f8285d4
Autor:
Joshua S. Danoff, Emma A. Page, Allison M. Perkeybile, William M. Kenkel, Jason R. Yee, Craig F. Ferris, C. Sue Carter, Jessica J. Connelly
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
The neurohormone oxytocin regulates many aspects of physiology primarily by binding to its receptor, the oxytocin receptor. The oxytocin receptor gene (Oxtr) has been shown to have alternative transcripts in the mouse brain which may each have differ
Externí odkaz:
https://doaj.org/article/d830f27abe7e4a6f9d68155600d19e4d
Autor:
Brittany M. Brems, Erin E. Sullivan, Jenna G. Connolly, Jingchun Zhang, Arnold Chang, Richard Ortiz, Lucas Cantwell, Praveen Kulkarni, Ganesh A. Thakur, Craig F. Ferris
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundAlpha 7 nicotinic acetylcholine receptor (α7nAChR) agonists have been developed to treat schizophrenia but failed in clinical trials due to rapid desensitization. GAT107, a type 2 allosteric agonist-positive allosteric modulator (ago-PAM)
Externí odkaz:
https://doaj.org/article/0eedf5d674d74d6d9c71bd536849d86c
Autor:
Katrina A. Milbocker, Gillian L. LeBlanc, Eric K. Brengel, Khan S. Hekmatyar, Praveen Kulkarni, Craig F. Ferris, Anna Y. Klintsova
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract 1 in 20 live births in the United States is affected by prenatal alcohol exposure annually, creating a major public health crisis. The teratogenic impact of alcohol on physical growth, neurodevelopment, and behavior is extensive, together re
Externí odkaz:
https://doaj.org/article/d6b896fd23f341a3bd3416cf82f2b2a8