Zobrazeno 1 - 10
of 6 580
pro vyhledávání: '"A. Esteller"'
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 304-311 (2024)
The identification of mechanisms capable of modifying genetic information by the addition of covalent RNA modifications distinguishes a level of complexity in gene expression which challenges key long-standing concepts of RNA biology. One of the curr
Externí odkaz:
https://doaj.org/article/4ea947f99ba944dcb9cfb48246e9d20d
Autor:
Umberto Perron, Elena Grassi, Aikaterini Chatzipli, Marco Viviani, Emre Karakoc, Lucia Trastulla, Lorenzo M. Brochier, Claudio Isella, Eugenia R. Zanella, Hagen Klett, Ivan Molineris, Julia Schueler, Manel Esteller, Enzo Medico, Nathalie Conte, Ultan McDermott, Livio Trusolino, Andrea Bertotti, Francesco Iorio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Patient-derived xenografts (PDXs) are tumour fragments engrafted into mice for preclinical studies. PDXs offer clear advantages over simpler in vitro cancer models - such as cancer cell lines (CCLs) and organoids - in terms of structural com
Externí odkaz:
https://doaj.org/article/e3eb9c07dbae4f8bbe9a18205016643b
Autor:
María Gallardo‐Gómez, Lara Costas‐Ríos, Carlos A. Garcia‐Prieto, Lara Álvarez‐Rodríguez, Luis Bujanda, Maialen Barrero, Antoni Castells, Francesc Balaguer, Rodrigo Jover, Manel Esteller, Antoni Tardío Baiges, Joaquín González‐Carreró Fojón, Joaquín Cubiella, Loretta De Chiara
Publikováno v:
Molecular Oncology, Vol 18, Iss 11, Pp 2696-2713 (2024)
The clinical relevance of the colorectal cancer serrated pathway is evident, but the screening of serrated lesions remains challenging. We aimed to characterize the serum methylome of the serrated pathway and to evaluate circulating cell‐free DNA (
Externí odkaz:
https://doaj.org/article/52a5b5b7bba14705bc89a233d4909de9
Autor:
Sandhya Malla, Kanchan Kumari, Carlos A. García-Prieto, Jonatan Caroli, Anna Nordin, Trinh T. T. Phan, Devi Prasad Bhattarai, Carlos Martinez-Gamero, Eshagh Dorafshan, Stephanie Stransky, Damiana Álvarez-Errico, Paulina Avovome Saiki, Weiyi Lai, Cong Lyu, Ludvig Lizana, Jonathan D. Gilthorpe, Hailin Wang, Simone Sidoli, Andre Mateus, Dung-Fang Lee, Claudio Cantù, Manel Esteller, Andrea Mattevi, Angel-Carlos Roman, Francesca Aguilo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Lysine-specific histone demethylase 1 (LSD1), which demethylates mono- or di- methylated histone H3 on lysine 4 (H3K4me1/2), is essential for early embryogenesis and development. Here we show that LSD1 is dispensable for mouse embryonic stem
Externí odkaz:
https://doaj.org/article/2d6f847ecfc84532b688deb0fc0250d8
Autor:
D. Esteller Gauxax, A. Minguillón Pereiro, B. Martins, J. Sarto Alonso, N. Guillén Soley, N. Falgàs, S. Borrego Écija, A. Tort Merino, M. Castellví, B. Bosch Capdevila, J. Juncà Parella, A. del Val, G. Fernández Villullas, R. Ruiz García, L. Naranjo, R. Puey, A. Antonell, A. Lladó Plarrumaní, R. Sánchez-Valle Díaz, M. Balasa
Publikováno v:
Neurology Perspectives, Vol 4, Iss , Pp 18- (2024)
Externí odkaz:
https://doaj.org/article/8c5407e02d7f4cb79a892c277e7a043e
Autor:
J. Sarto Alonso, D. Esteller-Gauxax, N. Guillén, N. Falgàs, S. BorregoÉcija, G. Fernández-Villullas, Y. González, A. Alberique, A. Tort- Merino, J. Juncà-Parella, A. del Val, B. Bosch-Capdevila, R. Puey, A. Colmenero, S. de la Fuente, A. Antonell, L. Naranjo, R. Ruiz- García, J. Augé, R. Sánchez-Valle, A. Lladó, M. Balasa
Publikováno v:
Neurology Perspectives, Vol 4, Iss , Pp 22- (2024)
Externí odkaz:
https://doaj.org/article/bbb85c9bf9b4420ea8228ccbbb80b1e7
Autor:
A. Tort Merino, A. Pérez-Millán, N. Falgàs, S. Borrego-Écija, N. Guillén, J. Sarto, D. Esteller, B. Bosch, M. Castellví, J. Juncà- Parella, A. del Val, G. Fernández-Villullas, A. Antonell, M. Sánchez-Saudinós, S. Rubio-Guerra, N. Zhu, M. García-Martínez, A. Pozueta, A. Estanga, M. Ecay-Torres, C. López de Luis, M. Tainta, M. Altuna, E. Rodríguez-Rodríguez, P. Sánchez-Juan, P. Martínez-Lage, A. Lleó, J. Fortea, I. Illán-Gala, M. Balasa, A. Lladó, L. Rami, R. Sánchez-Valle
Publikováno v:
Neurology Perspectives, Vol 4, Iss , Pp 176- (2024)
Externí odkaz:
https://doaj.org/article/f3fef9ab903f48c3bb7cea73ecfe0c2a
Autor:
Lorenzo-Esteller, Laia1 (AUTHOR) llorenzo@bellvitgehospital.cat, Ramos-Polo, Raúl1,2,3 (AUTHOR) rramosp@bellvitgehospital.cat, Pons Riverola, Alexandra1,2,3 (AUTHOR) herminiomorillas@bellvitgehospital.cat, Morillas, Herminio1,2,3 (AUTHOR), Berdejo, Javier1,2 (AUTHOR), Pernas, Sonia4 (AUTHOR) spernas@iconcologia.net, Pomares, Helena5 (AUTHOR), Asiain, Leyre6 (AUTHOR) lasiain@iconcologia.net, Garay, Alberto1,2,3,7 (AUTHOR), Martínez Pérez, Evelyn6 (AUTHOR), Jiménez-Marrero, Santiago1,2,3,8 (AUTHOR), Alcoberro, Lidia1,3 (AUTHOR), Nadal, Ernest4,7 (AUTHOR), Gubern-Prieto, Paula4 (AUTHOR), Gual-Capllonch, Francisco9 (AUTHOR), Hidalgo, Encarna1,2 (AUTHOR), Enjuanes, Cristina1,3,8 (AUTHOR), Comin-Colet, Josep1,3,8,10 (AUTHOR), Moliner, Pedro1,2,3,8 (AUTHOR) pmoliner@bellvitgehospital.cat
Publikováno v:
Cancers. Oct2024, Vol. 16 Issue 20, p3466. 14p.
Autor:
Laura Lorenzo-Sanz, Marta Lopez-Cerda, Victoria da Silva-Diz, Marta H. Artés, Sandra Llop, Rosa M. Penin, Josep Oriol Bermejo, Eva Gonzalez-Suarez, Manel Esteller, Francesc Viñals, Enrique Espinosa, Marc Oliva, Josep M. Piulats, Juan Martin-Liberal, Purificación Muñoz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Immune checkpoint blockade (ICB) approaches have changed the therapeutic landscape for many tumor types. However, half of cutaneous squamous cell carcinoma (cSCC) patients remain unresponsive or develop resistance. Here, we show that, during
Externí odkaz:
https://doaj.org/article/6c15c4009def405287d24b7b6ae51b70
Autor:
Joan Jiménez-Balado, Isabel Fernández-Pérez, Cristina Gallego-Fábrega, Uxue Lazcano, Carolina Soriano-Tárraga, Marta Vallverdú-Prats, Marina Mola-Caminal, Lucía Rey-Álvarez, Adrià Macias-Gómez, Antoni Suárez-Pérez, Eva Giralt-Steinhauer, Ana Rodríguez-Campello, Elisa Cuadrado-Godia, Ángel Ois, Manel Esteller, Jaume Roquer, Israel Fernández-Cadenas, Jordi Jiménez-Conde
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background and aims Stroke is the leading cause of adult-onset disability. Although clinical factors influence stroke outcome, there is a significant variability among individuals that may be attributed to genetics and epigenetics, including
Externí odkaz:
https://doaj.org/article/3f0b1b34c1ca432b9a498408bb37c80e