Zobrazeno 1 - 10
of 2 662
pro vyhledávání: '"A. E. Powell"'
Autor:
Taylor P. van Doren, Ryan A. Brown, Guangqing Chi, Patricia Cochran, Katie Cueva, Laura Eichelberger, Ruby Fried, Stacey Fritz, Micah B. Hahn, Ron Heintz, Davin Holen, Noor Johnson, Josée Lavoie, Emily Maxwell, Lisa McNair, Todd Nicewonger, Robert W. Orttung, Andrey N. Petrov, James E. Powell
Publikováno v:
International Journal of Circumpolar Health, Vol 83, Iss 1 (2024)
Pandemics are regularly occurring events, and there are foundational principles of pandemic preparation upon which communities, regions, states, and nations may draw upon for elevated preparedness against an inevitable future infectious disease threa
Externí odkaz:
https://doaj.org/article/75493e4d93da491c9ceeee24556eceac
Publikováno v:
The Cryosphere, Vol 18, Pp 2969-2978 (2024)
Determining recent Antarctic ice volume changes from satellite altimeter measurements of ice surface height requires a correction for contemporaneous vertical crustal deformation. This correction must consider two main sources of crustal deformation:
Externí odkaz:
https://doaj.org/article/533e89be190746d985ff540f824a023e
Autor:
Patricia C. Valery, Shruti Roche, Catherine Brown, James O’Beirne, Gunter Hartel, Barbara Leggett, Richard Skoien, Elizabeth E. Powell
Publikováno v:
International Journal for Equity in Health, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Liver disease is an important contributor to the mortality gap between First Nations Peoples and non-Indigenous Australian adults. Despite a high burden of metabolic comorbidities among First Nations Peoples, data about the epidem
Externí odkaz:
https://doaj.org/article/05df21a0938d433fa47b86ba1a600ac8
Autor:
Drew Neavin, Anne Senabouth, Himanshi Arora, Jimmy Tsz Hang Lee, Aida Ripoll-Cladellas, sc-eQTLGen Consortium, Lude Franke, Shyam Prabhakar, Chun Jimmie Ye, Davis J. McCarthy, Marta Melé, Martin Hemberg, Joseph E. Powell
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Recent innovations in single-cell RNA-sequencing (scRNA-seq) provide the technology to investigate biological questions at cellular resolution. Pooling cells from multiple individuals has become a common strategy, and droplets can subsequent
Externí odkaz:
https://doaj.org/article/7209fadf8e984cfb87325f01f83f0d88
Autor:
Karl D. Castillo, Colleen B. Bove, Annabel M. Hughes, Maya E. Powell, Justin B. Ries, Sarah W. Davies
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Local adaptation can increase fitness under stable environmental conditions. However, in rapidly changing environments, compensatory mechanisms enabled through plasticity may better promote fitness. Climate change is causing devastating impa
Externí odkaz:
https://doaj.org/article/eed5976a57994775ba59da48099a590a
Autor:
Elizabeth E Powell, Shruti Roche, Babak Sarraf, Gunter Hartel, Richard Skoien, Barbara Leggett, James O'Beirne, Patricia C Valery
Publikováno v:
JGH Open, Vol 8, Iss 7, Pp n/a-n/a (2024)
Abstract Background and Aim Metabolic dysfunction‐associated steatotic liver disease (MASLD) is associated with an increased risk of extrahepatic morbidity. We compared the incidence of cancers in adults admitted to Queensland hospitals with MASLD
Externí odkaz:
https://doaj.org/article/228bb71fdb25447e8efe6f6bb341faa9
Autor:
Connor J. Greatbatch, MBBS, Qinyi Lu, MD, PhD, Sandy Hung, PhD, Son N. Tran, PhD, Kristof Wing, MBBS, Helena Liang, MD, PhD, Xikun Han, PhD, Tiger Zhou, FRANZCO, PhD, Owen M. Siggs, MD, PhD, David A. Mackey, FRANZCO, MD, Guei-Sheung Liu, PhD, Anthony L. Cook, PhD, Joseph E. Powell, PhD, Jamie E. Craig, FRANZCO, DPhil, Stuart MacGregor, PhD, Alex W. Hewitt, FRANZCO, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 4, Pp 100504- (2024)
Purpose: Genome-wide association studies have recently uncovered many loci associated with variation in intraocular pressure (IOP). Artificial intelligence (AI) can be used to interrogate the effect of specific genetic knockouts on the morphology of
Externí odkaz:
https://doaj.org/article/abb1ee8966924ea990c570465f440c02
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-3 (2024)
Abstract Cancer stem cell plasticity refers to the ability of tumour cells to dynamically switch between states—for example, from cancer stem cells to non-cancer stem cell states. Governed by regulatory processes, cells transition through a continu
Externí odkaz:
https://doaj.org/article/77fd9a26b5714ce78a0e2fae366b13d7
Autor:
Kelly L. Hayward, Rianne A. Weersink, Christina M. Bernardes, Carolyn McIvor, Tony Rahman, Richard Skoien, Paul J. Clark, Katherine A. Stuart, Gunter Hartel, Patricia C. Valery, Elizabeth E. Powell
Publikováno v:
Drugs - Real World Outcomes, Vol 10, Iss 4, Pp 605-618 (2023)
Abstract Background Safe and appropriate use of medicines is essential to improve health outcomes in cirrhosis. However, little is known about the number and type of medicines dispensed to people with cirrhosis in Australia, as this predominantly occ
Externí odkaz:
https://doaj.org/article/40886e4eb468447dbe94b569820c8af7
Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins
Autor:
M. Alejandra Zeballos C., Hayden J. Moore, Tyler J. Smith, Jackson E. Powell, Najah S. Ahsan, Sijia Zhang, Thomas Gaj
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The TDP-43 proteinopathies, which include amyotrophic lateral sclerosis and frontotemporal dementia, are a devastating group of neurodegenerative disorders that are characterized by the mislocalization and aggregation of TDP-43. Here we demo
Externí odkaz:
https://doaj.org/article/806043219e3c4fd2992e4a49b1c8a963