Method of derivation and differentiation of mouse embryonic stem cells generating synchronous neuronal networks

Autor: Joseph Chen, Elena V. Gazina, Martin F. Pera, Emma Morrisroe, Christian M. Nefzger, Steven Petrou, Benjamin N. Rollo, Gunarathna D.C. Mendis, Christopher A. Reid, Anna E. Michalska

Publikováno v: Journal of Neuroscience Methods. 293:53-58

Background: Stem cells-derived neuronal cultures hold great promise for in vitro disease modelling and drug screening. However, currently stem cells-derived neuronal cultures do not recapitulate the functional properties of primary neurons, such as n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec66c190a50b18fe99cff3788bf82b77
https://doi.org/10.1016/j.jneumeth.2017.08.018

Generation of Induced Pluripotent Stem Cell Lines from Friedreich Ataxia Patients

Autor: Jessie Leung, Jun Liu, Duncan E. Crombie, Anna E. Michalska, Martin B. Delatycki, Mirella Dottori, Robert Williamson, Paul J. Verma, Joseph P. Sarsero, Marguerite V. Evans-Galea, Alice Pébay

Publikováno v: Stem Cell Reviews and Reports. 7:703-713

Friedreich ataxia (FRDA) is an autosomal recessive disorder characterised by neurodegeneration and cardiomyopathy. It is caused by a trinucleotide (GAA) repeat expansion in the first intron of the FXN gene that results in reduced synthesis of FXN mRN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7619ecc4a68f3766219bfe8f5f0cadd
https://doi.org/10.1007/s12015-010-9210-x

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

Autor: Nissim Benvenisty, Minal Patel, Glyn Stacey, Lesley Young, Sanna Vuoristo, Barak Blum, Robert Passier, Steve Oh, Rebecca S. Hamilton, Miodrag Stojkovic, Barbara B. Knowles, Benjamin Reubinoff, Kehkooi Kee, Barbara S. Mallon, Andras Nagy, Michal Amit, Janet Rossant, Paul J. Gokhale, Franck Lebrin, Henrike Siemen, Simon Bevan, Weidong Zhang, Milla Mikkola, Stephen L. Minger, Norio Nakatsuji, Peter W. Andrews, Eric S Sherrer, Paul Bello, Tikva Turetsky, Lorraine S. Berry, Behrouz Aflatoonian, Christine L. Mummery, Masha Mileikovsky, Yoav Mayshar, Angela Ford, Harry Moore, Mark Jones, Joseph Itskovitz-Eldor, Jackie Johnson, Lars Ährlund-Richter, Roland A. Fleck, Oluseun Adewumi, Jamie P. Jackson, Alex Hampl, Andre Bh Choo, Petr Dvorak, Timo Otonkoski, Daisy Manning, Henrik Semb, Marta P. Imreh, Justin Brooking, Marina Gertsenstein, Dorien Ward, Jin P. Szatkiewicz, Timo Tuuri, Thomas C Schulz, Marian S Piekarczyk, Kevin G. Chen, Karin Astrid Maria Gertow, Renee A. Reijo Pera, Thomas A Weaver, Gemma Beighton, Kye-Yoon Park, Majlinda Lako, Ronald D.G. McKay, Katarina Emanuelsson, Cia Olsson, Carmel M. O’Brien, Johan Hyllner, Hema Patel, Outi Hovatta, Allan J. Robins, Hirofumi Suemori, Peter J. Rugg-Gunn, Martin F. Pera, Marie Corbel, Gary A. Churchill, Ivan Damjanov, John S Draper, Benjamin L. King, Lyn Healy, Steineke van den Brink, Roger A. Pedersen, Anna E. Michalska, Kristina Vintersten

Publikováno v: Nature Biotechnology. 25:803-816

The International Stem Cell Initiative characterized 59 human embryonic stem cell lines from 17 laboratories worldwide. Despite diverse genotypes and different techniques used for derivation and maintenance, all lines exhibited similar expression pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867a067cc25cab7204dd3712d4e89593
https://doi.org/10.1038/nbt1318

Lack of metallothionein-I and -II exacerbates the immunosuppressive effect of ultraviolet B radiation andcis-urocanic acid in mice

Autor: Vivienne E. Reeve, Meira Bosnic, K. H. A. Choo, A. E. Michalska, Noriko Nishimura

Publikováno v: Immunology. 100:399-404

The effect of a null mutation for the metallothionein (MT)-I and -II isoforms in mice on the immunosuppressive action of ultraviolet B (UVB; 280-320 nm) radiation has been examined. Mice were exposed to a series of increasing daily UVB doses, each do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4d819a800a3fb52e45fd90a68355121
https://doi.org/10.1046/j.1365-2567.2000.00026.x

Reduced retention of cadmium in the liver of metallothionein-null mice

Autor: Masahiko Satoh, Yoshitaka Kanayama, Andy Choo, Chiharu Tohyama, Akira Naganuma, Naomi Kodama, A. E. Michalska, Hisao Nishimura

Publikováno v: Environmental Toxicology and Pharmacology. 1:213-216

The distribution of cadmium (Cd) in the organs of mice was studied using metallothionein (MT)-null transgenic mice. When mice were administered with Cd chloride at a single subcutaneous dose of 1.0 mg Cd/kg body weight, Cd accumulated mainly in the l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42280c22eb343be4b674a4d832792b58
https://doi.org/10.1016/1382-6689(96)00014-2