Zobrazeno 1 - 10
of 34
pro vyhledávání: '"A. E. Marneth"'
Autor:
J. S. Jutzi, A. E. Marneth, M. J. Jimenez-Santos, A. Guerra-Moreno, S. A. Myers, S. A. Carr, P. van Galen, F. Al-Shahrour, A. S. Nam, A. Mullally
Publikováno v:
HemaSphere, Vol 6, Pp 92-93 (2022)
Externí odkaz:
https://doaj.org/article/2d045ef5f4ac4b75af1f26846a5b6cc8
Publikováno v:
Frontiers in Hematology, Vol 3 (2024)
Although the involvement of glycan structures in diseases has long been recognized, their detailed and high-throughput investigation has only recently been made possible due to technological advancements. For this reason, glycosylation is a generally
Externí odkaz:
https://doaj.org/article/f89846b58b844d87a675276b1b42b307
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/14c8901f764747f4a4997f90636fb002
Autor:
Julie Ng, Anna E. Marneth, Alec Griffith, Daniel Younger, Sailaja Ghanta, Alan Jiao, Gareth Willis, Junwen Han, Jewel Imani, Bailin Niu, Joshua W. Keegan, Brandon Hancock, Fei Guo, Yang Shi, Mark A. Perrella, James A. Lederer
Publikováno v:
Journal of Innate Immunity, Vol 15, Iss 1, Pp 765-781 (2023)
Novel therapeutics are urgently needed to prevent opportunistic infections in immunocompromised individuals undergoing cancer treatments or other immune-suppressive therapies. Trained immunity is a promising strategy to reduce this burden of disease.
Externí odkaz:
https://doaj.org/article/12ec38b6a3d0419793c624e7617e2e10
Autor:
Jonas S. Jutzi, Anna E. Marneth, María José Jiménez-Santos, Jessica Hem, Angel Guerra-Moreno, Benjamin Rolles, Shruti Bhatt, Samuel A. Myers, Steven A. Carr, Yuning Hong, Olga Pozdnyakova, Peter van Galen, Fátima Al-Shahrour, Anna S. Nam, Ann Mullally
Publikováno v:
Leukemia. 37:359-369
Cancer is driven by somatic mutations that provide a fitness advantage. While targeted therapies often focus on the mutated gene or its direct downstream effectors, imbalances brought on by cell-state alterations may also confer unique vulnerabilitie
Autor:
Anna E. Marneth, Ann Mullally
Publikováno v:
Haematologica, Vol 105, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/8d8a195321934f5bbe8e957715f12fd1
Autor:
Marten Hansen, Eszter Varga, Tatjana Wüst, Clemens Mellink, Anne-Marie van der Kevie-Kersemaekers, Anne E. Marneth, Marieke von Lindern, Bert van der Reijden, Emile van den Akker
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 34-37 (2017)
Peripheral blood mononuclear cells were isolated from an individual harboring a heterozygous c.859C → T p.Q287* mutation in GFI1B, causing an autosomal dominant bleeding disorder, platelet type, 17 (BDPLT17). PBMCs were differentiated to erythrobla
Externí odkaz:
https://doaj.org/article/91a2cfd943dd436f9e9a8fa9f4e6c4e8
Autor:
Jonas S. Jutzi, Anna E. Marneth, Michele Ciboddo, Angel Guerra-Moreno, María José Jiménez-Santos, Anastasia Kosmidou, James W. Dressman, Hongyan Liang, Rebecca Hamel, Patricia Lozano, Elisa Rumi, John G. Doench, Jason Gotlib, Anandi Krishnan, Shannon Elf, Fátima Al-Shahrour, Ann Mullally
Publikováno v:
Blood
Calreticulin (CALR) mutations are frequent, disease-initiating events in myeloproliferative neoplasms (MPNs). Although the biological mechanism by which CALR mutations cause MPNs has been elucidated, there currently are no clonally selective therapie
Autor:
Kyle H. Vining, Anna E. Marneth, Kwasi Adu-Berchie, Joshua M. Grolman, Christina M. Tringides, Yutong Liu, Waihay J. Wong, Olga Pozdnyakova, Mariano Severgnini, Alexander Stafford, Georg N. Duda, F. Stephen Hodi, Ann Mullally, Kai W. Wucherpfennig, David J. Mooney
Publikováno v:
Nature Materials. 21:939-950
Autor:
Rinske van Oorschot, Marten Hansen, Johanna M. Koornneef, Anna E. Marneth, Saskia M. Bergevoet, Maaike G.J.M. van Bergen, Floris P.J. van Alphen, Carmen van der Zwaan, Joost H.A. Martens, Michiel Vermeulen, Pascal W.T.C. Jansen, Marijke P.A. Baltissen, Britta A.P. Laros-van Gorkom, Hans Janssen, Joop H. Jansen, Marieke von Lindern, Alexander B. Meijer, Emile van den Akker, Bert A. van der Reijden
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
Dominant-negative mutations in the transcription factor Growth Factor Independence-1B (GFI1B), such as GFI1BQ287*, cause a bleeding disorder characterized by a plethora of megakaryocyte and platelet abnormalities. The deregulated molecular mechanisms
Externí odkaz:
https://doaj.org/article/fa460826edfb42dbb79b809d6ce5fa66