Zobrazeno 1 - 10
of 33
pro vyhledávání: '"A. E. M. Mautes"'
Autor:
Cosmin Glameanu, Wolf-Ingo Steudel, Jacek Szczygielski, Angelika E. M. Mautes, Andreas Müller, Christoph Sippl, Karsten Schwerdtfeger, Joachim Oertel
Publikováno v:
Journal of Neurotrauma. 34:1623-1635
Hypothermia and decompressive craniectomy (DC) have been considered as treatment for traumatic brain injury. The present study investigates whether selective brain hypothermia added to craniectomy could improve neurological outcome after brain trauma
Publikováno v:
Journal of Molecular Neuroscience. 31:95-100
In the present investigation we examined regional ATP, glucose, and lactate content in the cortical and subcortical region, in a mouse model of controlled cortcal impact (CCI) injury. In serial tissue sections, bioluminescence imaging of ATP, glucose
Autor:
Wolf-Ingo Steudel, Jacek Szczygielski, Cosmin Glameanu, Karsten Schwerdtfeger, Andreas Müller, Joachim Oertel, Christoph Sippl, Angelika E. M. Mautes
Publikováno v:
Journal of neurotrauma. 33(1)
Decompressive craniectomy has been widely used in patients with head trauma. The randomized clinical trial on an early decompression (DECRA) demonstrated that craniectomy did not improve the neurological outcome, in contrast to previous animal experi
Autor:
Jacek Szczygielski, Oliver Wirths, Peter Falkai, Thomas A. Bayer, Wolf-Ingo Steudel, Angelika E. M. Mautes
Publikováno v:
Journal of Neural Transmission. 112:1547-1564
Traumatic Brain Injury is the leading cause of death and disability among young individuals in our society. Moreover, according to some epidemiological studies, head trauma is one of the most potent environmental risk factors for subsequent developme
Publikováno v:
Intensivmedizin und Notfallmedizin. 41:71-80
Every year, approximately 55,000 patients suffering from spinal trauma require hospital care in Germany. About 20% of these patients have symptoms of a spinal cord injury. It is important to know that vertebral column injury may be associated with sp
Autor:
Gerhard F. Hamann, Markus Benz, Dorothe Burggraf, Christian U.A. Kloss, Angela Muellner, Angelika E. M. Mautes
Publikováno v:
Journal of Neurotrauma. 20:745-754
The loss of microvascular basal lamina antigen is known to be a consequence of cerebral ischemia, but little information is available on its role in traumatic brain injury (TBI). The aim of our study was (1) to test the hypothesis that there is damag
Publikováno v:
Journal of Anatomy. 203:21-29
Changes in the histochemical profile of 43 rat extensor digitorum longus muscles undergoing de-innervation and re-innervation were recorded. Assessment of fibre type composition and muscle fibre cross-sectional area was performed at 15, 30, 90 and 18
Autor:
Markus Paxian, Hartmut Jaeschke, T. Beate Wolf, Silke Jeblick, Stefan A. Kolb, Michael Bauer, Hauke Rensing, Inge Bauer, Andre Stockhausen, Angelika E. M. Mautes
Publikováno v:
The FASEB Journal. 17:993-1002
Progressive liver dysfunction contributes significantly to the development of multiple organ failure after trauma/hemorrhage. This study tested the relative impact of necrotic and apoptotic cell death in a graded model of hemorrhagic shock (mean arte
Publikováno v:
Neuroscience Letters. 336:13-16
Induction of heme oxygenase-1 (HO-1) in the spinal cord was studied in adult wildtype and transgenic mice overexpressing the antioxidant copper, zinc superoxide dismutase (CuZn SOD) 24 h after intrathecal infusion of heterologous lysed blood. Double
Publikováno v:
European Journal of Trauma. 28:143-156
Treatment in the Acute Phase: Processes of secondary injury significantly enlarge tissue damage after spinal cord injury (SCI). Ischemic and inflammatory processes play a major role. Animal models have shown that in the acute stage, there are numerou