Zobrazeno 1 - 10
of 147
pro vyhledávání: '"A. E. Hedin"'
Autor:
Rosalie M. Sterner, BS, BA, Karen E. Hedin, PhD, Richard E. Hayden, MD, Grzegorz S. Nowakowski, MD, Saranya P. Wyles, MD, PhD, Alexandra J. Greenberg-Worisek, PhD, Andre Terzic, MD, PhD, Saad S. Kenderian, MB, ChB
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 4, Iss 2, Pp 203-210 (2020)
Objective: To evaluate the impact of a novel interdisciplinary graduate-level course in chimeric antigenic receptor-T cell therapy on students’ knowledge and interests in translational science. Materials/Participants and Methods: The course ran Nov
Externí odkaz:
https://doaj.org/article/7bf60d0753414707a80b9db0a9f8fecc
Autor:
Kasey R. Boehmer, Suelen Lucio Boschen De Souza, Jason D. Doles, Nirusha Lachman, Dennis Mays, Karen E. Hedin, Cheryl A. Dornink, Louis J. Maher, J. Luis Lujan
Publikováno v:
Frontiers in Education, Vol 6 (2021)
Tactics to increase the number of underrepresented (UR) students in biomedical research PhD training programs have not yet translated to UR faculty numbers that reflect the diversity of the United States. Continued interventions are required to build
Externí odkaz:
https://doaj.org/article/0571700eaa584a47b945339df0881dc0
Autor:
Keith L. Knutson, Ellen L. Goode, Allan B. Dietz, Karen E. Hedin, Haidong Dong, Jo Marie T. Janco, Lynn C. Hartmann, Doris M. Vargas, Marshall D. Behrens, Kimberly R. Kalli, James Krempski, Purushottam Lamichhane, Lavakumar Karyampudi
The PD-1:PD-L1 immune signaling axis mediates suppression of T-cell–dependent tumor immunity. PD-1 expression was recently found to be upregulated on tumor-infiltrating murine (CD11c+CD11b+CD8−CD209a+) and human (CD1c+CD19−) myeloid dendritic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ad0d8e422bb7e0df9b2979850132fa4
https://doi.org/10.1158/0008-5472.c.6507603.v1
https://doi.org/10.1158/0008-5472.c.6507603.v1
Autor:
Keith L. Knutson, Ellen L. Goode, Allan B. Dietz, Karen E. Hedin, Haidong Dong, Jo Marie T. Janco, Lynn C. Hartmann, Doris M. Vargas, Marshall D. Behrens, Kimberly R. Kalli, James Krempski, Purushottam Lamichhane, Lavakumar Karyampudi
Supplementary methods and figures. Fig. 1:TIDCs obtained from the ascites from ovarian cancer patients express PD-1 mRNA. Fig. 2: TIDCs obtained from the ascites of ID8 tumor bearing mice express PD-1 mRNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f20ab553c288b1d20f4a2652ba3641
https://doi.org/10.1158/0008-5472.22408743.v1
https://doi.org/10.1158/0008-5472.22408743.v1
Autor:
Bradley Bowles, Rosalie M. Sterner, Kimberly N. Kremer, Amel Dudakovic, Jennifer J. Westendorf, Andre J. Van Wijnen, Karen E. Hedin
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 26-27 (2018)
OBJECTIVES/SPECIFIC AIMS: Treatment of acute myeloid leukemia (AML) is challenging, as apoptosis-resistant AML cells often persist within the bone marrow microenvironment despite chemotherapy. The overall goal of our laboratory is to identify and ult
Externí odkaz:
https://doaj.org/article/fc5bd80785b344ac88bb728474f4f544
Autor:
J Sorensen, J Bergsten, T Baron, L H Orndahl, T Kero, T Bjerner, E Hedin, H J Harms, F A Flacshkampf
Publikováno v:
European Heart Journal. 42
Objectives To study the association of myocardial external efficiency (MEE) in mitral regurgitation (MR) towards routinely used quantitative indicators of disease severity and progression. Background Quantitative assessment of LV function and regurgi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1581018e81e7728e3e5f09077fa3d0c
https://doi.org/10.1093/eurheartj/ehab724.1610
https://doi.org/10.1093/eurheartj/ehab724.1610
Autor:
Joanna Kim, Michael J Shapiro, Adebowale O Bamidele, Pinar Gurel, Puspa Thapa, Henry N Higgs, Karen E Hedin, Virginia S Shapiro, Daniel D Billadeau
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85090 (2014)
Actin depolymerizing factor-homology (ADF-H) family proteins regulate actin filament dynamics at multiple cellular locations. Herein, we have investigated the function of the ADF-H family member coactosin-like 1 (COTL1) in the regulation of actin dyn
Externí odkaz:
https://doaj.org/article/aa4b7635dda546b7946f964eb2927511
Publikováno v:
Journal of Biological Chemistry. 293:14022-14039
The immune system includes abundant examples of biologically-relevant cross-regulation of signaling pathways by the T cell antigen receptor (TCR) and the G protein-coupled chemokine receptor, CXCR4. TCR ligation induces transactivation of CXCR4 and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d3eb0cee79e609a2f55ab408ecfc02
https://doi.org/10.1074/jbc.ra118.003097
https://doi.org/10.1074/jbc.ra118.003097
Autor:
Rosalie M. Sterner, Aref Al-Kali, Mrinal M. Patnaik, Naseema Gangat, Scott H. Kaufmann, Andre J. van Wijnen, Mark R. Litzow, Kimberly N. Kremer, Jennifer J. Westendorf, Karen E. Hedin
Publikováno v:
Oncotarget
The bone marrow microenvironment protects acute myeloid leukemia (AML) cells during chemotherapy and is a major factor in relapse. Here, we examined which type(s) of bone marrow cells are responsible for the relapse of AML following treatment with cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95146c468330c1336c2fbcf3e318614
http://europepmc.org/articles/PMC5706896
http://europepmc.org/articles/PMC5706896
Autor:
Rosalie M. Sterner, Fang Jin, Omar H. Ahmed, Karen E. Hedin, Katayoun Ayasoufi, Denise K. Walters, Nan Yang, Cynthia L. Forsman, Tarek Sahmoud, Michelle J. Cox, Michael J. Hansen, Reona Sakemura, Dale Chappell, Aaron J. Johnson, Larry R. Pease, Wendy K. Nevala, Neil E. Kay, Mehrdad Hefazi, Mrinal M. Patnaik, Saad S. Kenderian, Kendall J. Schick, Roman H. Khadka, Cameron Durrant
Chimeric antigen receptor T (CAR-T) cell therapy is a new pillar in cancer therapeutics; however, its application is limited by the associated toxicities. These include cytokine release syndrome (CRS) and neurotoxicity. Although the IL-6R antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f891ac68301275acaa9ef7ab31288b
https://europepmc.org/articles/PMC6376281/
https://europepmc.org/articles/PMC6376281/