Zobrazeno 1 - 7
of 7
pro vyhledávání: '"A. E. Hearron"'
Publikováno v:
European Journal of Clinical Pharmacology. 45:437-443
We have studied the pharmacokinetics and haemodynamic effects of nicorandil after a 12-h infusion. Nicorandil is a mixed vasodilator combining the actions of a nitrate and a potassium channel opener. Nicorandil was infused for 12 h in 21 healthy volu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009f0fadc736d5592372acd0f812b097
https://doi.org/10.1007/bf00315515
https://doi.org/10.1007/bf00315515
Publikováno v:
European Journal of Clinical Pharmacology. 44:27-33
We have studied the effects of intravenous nicorandil, a mixed arterial and venous vasodilator, in 48 healthy volunteers. Nicorandil (20, 28, 39, 54, 74, 103, 144, or 200 μg·kg−1) or placebo were given over 5 min to subjects supine (16 subjects,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0d109bc3ec8afcfd0768b78d124ff3
https://doi.org/10.1007/bf00315276
https://doi.org/10.1007/bf00315276
Autor:
Ileana L. Pina, R. Stephen Porter, Daniel L. Wolf, J. Scott Mohrland, Dean G. Karalis, Thomas D. Giles, Rhonda Zaleski, Louise Roffidal, Gary E. Sander, Antonio C. Quiroz, Arthur E. Hearron
Publikováno v:
Journal of Cardiovascular Pharmacology. 20:572-578
Nicorandil is a vasodilator drug that combines potassium channel opening properties with nitrate effects. The resulting potent and unique vasodilating properties suggest a potential therapeutic role in congestive heart failure. We therefore studied t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b62475c3a03596b82576038a59c9759
https://doi.org/10.1097/00005344-199210000-00010
https://doi.org/10.1097/00005344-199210000-00010
Autor:
Daniel L. Wolf, Arthur E. Hearron, Peter R. Kowey, Gail L. Jungbluth, J. Malcolm O. Arnold, John R. Luderer
Publikováno v:
International journal of cardiology. 44(3)
We studied the acute haemodynamic dose response of nicorandil, a combined nitrate and potassium channel opener, in patients evaluated for chest pain. Single dose oral nicorandil (5, 10, 20, or 30 mg) or placebo was given to 42 right-heart catheterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0df446c3d5a532f874d34e60384ccb
https://pubmed.ncbi.nlm.nih.gov/8077066
https://pubmed.ncbi.nlm.nih.gov/8077066
Autor:
A. R. Diani, T. Peterson, Karen Jodelis, G. A. Sawada, Barbara J. Gilchrist, Beatrice M. Wyse, Albert Chang, Arthur E. Hearron
Publikováno v:
Nephron. 42:72-77
Kidneys of treated and control C57BL/KsJ-db/db mice were analyzed by semiquantitative light microscopy to determine the effects of ciglitazone on the deposition of fluorescein-conjugated IgM and IgG a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a00de79da0cdb8f0af2ea0689d8c23
https://doi.org/10.1159/000183637
https://doi.org/10.1159/000183637
Autor:
A. R. Diani, A. E. Hearron, B. J. Gilchrist, Beatrice M. Wyse, G. A. Sawada, Albert Y. Chang, T. Peterson
Publikováno v:
Diabetologia. 27:225-234
Pancreases of treated and control male C57BL/6J-ob/ob and C57BL/KsJ-db/db mice were evaluated by qualitative and morphometric microscopic techniques to determine the effects of chronic ciglitazone treatment on the morphology of beta cells and surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28df81c3dba1f5c57e8eebeb3ef3a5a0
https://doi.org/10.1007/bf00273811
https://doi.org/10.1007/bf00273811
Autor:
A R, Diani, T, Peterson, G, Sawada, K, Jodelis, B M, Wyse, B J, Gilchrist, A E, Hearron, A Y, Chang
Publikováno v:
Nephron. 42(1)
Kidneys of treated and control C57BL/KsJ-db/db mice were analyzed by semiquantitative light microscopy to determine the effects of ciglitazone on the deposition of fluorescein-conjugated IgM and IgG and of PAS-positive material in the glomerular mesa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09d96e4dceb09526121f23274b2e2b4a
https://pubmed.ncbi.nlm.nih.gov/3941752
https://pubmed.ncbi.nlm.nih.gov/3941752