Zobrazeno 1 - 10
of 186
pro vyhledávání: '"A. E. Downie"'
Autor:
Kevin J. Selva, Pradhipa Ramanathan, Ebene R. Haycroft, Arnold Reynaldi, Deborah Cromer, Chee Wah Tan, Lin-Fa Wang, Bruce D. Wines, P. Mark Hogarth, Laura E. Downie, Samantha K. Davis, Ruth A. Purcell, Helen E. Kent, Jennifer A. Juno, Adam K. Wheatley, Miles P. Davenport, Stephen J. Kent, Amy W. Chung
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
Understanding mucosal antibody responses from SARS-CoV-2 infection and/or vaccination is crucial to develop strategies for longer term immunity, especially against emerging viral variants. We profiled serial paired mucosal and plasma antibodies from
Externí odkaz:
https://doaj.org/article/5642c4f059134a179ab08b3553b928dd
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Corneal immune cells interact with corneal sensory nerves during both homeostasis and inflammation. This study sought to evaluate temporal changes to corneal immune cell density in a mouse model of epithelial abrasion and nerve in
Externí odkaz:
https://doaj.org/article/d16eff70253f47ceb8e4e45884f08300
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
PurposeIn vivo confocal microscopy (IVCM) images are frequently used to quantify corneal epithelial immune cell (IC) density in clinical studies. There is currently limited evidence to inform the selection of a representative image sample size to yie
Externí odkaz:
https://doaj.org/article/babbfddc63df446cb0c458b57a75ca90
Autor:
Mengliang Wu, Laura E. Downie, Liam M. Grover, Richard J. A. Moakes, Saaeha Rauz, Ann Logan, Haihan Jiao, Lisa J. Hill, Holly R. Chinnery
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Abstract Background The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any injury or pathology of the corneal nerves increases the risk of dry eye disease and infection. This study aims t
Externí odkaz:
https://doaj.org/article/d5f36fedb2bc481d91af5d0c3e21f3a9
Autor:
Haihan Jiao, Laura E. Downie, Xin Huang, Mengliang Wu, Sara Oberrauch, Ryan J. Keenan, Laura H. Jacobson, Holly R. Chinnery
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Tauopathy in the central nervous system (CNS) is a histopathological hallmark of frontotemporal dementia (FTD) and Alzheimer’s disease (AD). Although AD is accompanied by various ocular changes, the effects of tauopathy on the i
Externí odkaz:
https://doaj.org/article/f8b031e4e4be4a85a5101403a03da0a7
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 12, p e1009714 (2021)
Hosts diverge widely in how, and how well, they defend themselves against infection and immunopathology. Why are hosts so heterogeneous? Both epidemiology and life history are commonly hypothesized to influence host immune strategy, but the relations
Externí odkaz:
https://doaj.org/article/47b01834dc0140508725180d34507050
Autor:
Melissa Barnett, Noel A. Brennan, Adrian S. Bruce, M.-L. Chantal Coles, W. Neil Charman, Laura E. Downie, Nathan Efron, Suzanne E. Efron, Klaus Ehrmann, Daddi Fadel, Kate Gifford, Paul Gifford, Lyndon W. Jones, John G. Lawrenson, Richard G. Lindsay, Carole Maldonado-Codina, John Meyler, Philip B. Morgan, Sarah L. Morgan, Alison Ng, Clare O'Donnell, David Ruston, Padmaja Sankaridurg, Marc-Mathias Schulze, Joe Tanner, Cindy Tromans, Stephen J. Vincent, Karen Walsh, Helen Wilson, James S. Wolffsohn, Graeme Young
Publikováno v:
Contact Lens Practice ISBN: 9780702084270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69ca063d6ab9fddd7444c3cfbb5a3b9f
https://doi.org/10.1016/b978-0-7020-8427-0.00056-8
https://doi.org/10.1016/b978-0-7020-8427-0.00056-8
Autor:
Laura E. Downie, Richard G. Lindsay
Publikováno v:
Contact Lens Practice ISBN: 9780702084270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3717e2609c2426ab944f0d6e72b79730
https://doi.org/10.1016/b978-0-7020-8427-0.00025-8
https://doi.org/10.1016/b978-0-7020-8427-0.00025-8
Autor:
Ching Yi Wu, Mengliang Wu, Xin Huang, Ben J. Gu, Carole Maldonado-Codina, Philip B. Morgan, Laura E. Downie, Holly R. Chinnery
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9589 (2022)
Meibomian gland orifices (MGOs) are located along the eyelid margin and secrete meibum into the tear film. The profile of resident innate immune cells (ICs) at this site is not well understood. The distribution and phenotype of resident ICs around MG
Externí odkaz:
https://doaj.org/article/35727b343d434283bd6d0849ebce7d51
Autor:
James S. Wolffsohn, Gareth Lingham, Laura E. Downie, Byki Huntjens, Takenori Inomata, Saleel Jivraj, Emmanuel Kobia-Acquah, Alex Muntz, Karim Mohamed-Noriega, Sotiris Plainis, Michael Read, Rony R. Sayegh, Sumeer Singh, Tor P. Utheim, Jennifer P. Craig
Publikováno v:
The Ocular Surface. 28:213-252