Zobrazeno 1 - 10
of 830
pro vyhledávání: '"A. E. Cummings"'
Autor:
Samantha F. Kornfeld, Sarah E. Cummings, Rebecca Yaworski, Yves De Repentigny, Sabrina Gagnon, Stephanie Zandee, Samaneh Fathi, Alexandre Prat, Rashmi Kothary
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Strategies for treating progressive multiple sclerosis (MS) remain limited. Here, we found that miR-145-5p is overabundant uniquely in chronic lesion tissues from secondary progressive MS patients. We induced both acute and chronic demyelina
Externí odkaz:
https://doaj.org/article/44c7ebcf25614e2aabf92ea59d7493d9
Autor:
Dawoon Jung, BPharm, Omayma A. Kishk, PharmD, Adnan T. Bhutta, MBBS, Ginny E. Cummings, CRNP, Hana M. El Sahly, MD, Manpreet K. Virk, MD, Brady S. Moffett, PharmD, MPH, MBA, Jennifer L. Morris Daniel, PharmD, Amy Watanabe, MS, Nicholas Fishbane, MSc, Karen L. Kotloff, MD, Kenan Gu, PhD, Varduhi Ghazaryan, MD, PhD, Jogarao V. S. Gobburu, PhD, MBA, Ayse Akcan-Arikan, MD, James D. Campbell, MD, MS
Publikováno v:
Critical Care Explorations, Vol 6, Iss 10, p e1159 (2024)
OBJECTIVES:. To investigate which independent factor(s) have an impact on the pharmacokinetics of vancomycin in critically ill children, develop an equation to predict the 24-hour area under the concentration-time curve from a trough concentration, a
Externí odkaz:
https://doaj.org/article/a34a6293aafe4e51a718ca5102e78dff
Autor:
Frederic St‐Denis‐Bissonnette, Shirley Qiu, Sarah E. Cummings, Melanie Kirkby, Yohannes Haile, Sarah Wassmer, Gauri Muradia, Jelica Mehic, Andrew Stalker, Amit Shrestha, Michele Ardolino, Seung‐Hwan Lee, Dylan Burger, Lisheng Wang, Jessie R. Lavoie
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 7, Pp n/a-n/a (2024)
Abstract Natural killer cell‐derived extracellular vesicles (NK‐EVs) are candidate biotherapeutics against various cancers. However, standardised potency assays are necessary for a reliable assessment of NK‐EVs' cytotoxicity. This study aims to
Externí odkaz:
https://doaj.org/article/e9c74a4ae6444282ad687844f70ffab3
Autor:
Helen P. Bartlett, Clinton C. Dawson, Cody M. Glickman, David W. Osborn, Christopher R. Evans, Benjamin J. Garcia, Lauren C. Frost, Jason E. Cummings, Nicholas Whittel, Richard A. Slayden, Jason W. Holder
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTTo address intracellular mycobacterial infections, we developed a cocktail of four enzymes that catalytically attack three layers of the mycobacterial envelope. This cocktail is delivered to macrophages, through a targeted liposome presented
Externí odkaz:
https://doaj.org/article/75c0c1c5c1174a9db6bee2933f0b4e4f
Autor:
Camilo Serrano Damha, Bryan E. Cummings, Meredith Schervish, Manabu Shiraiwa, Michael S. Waring, Andreas Zuend
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 3, Pp n/a-n/a (2024)
Abstract Aerosol water affects the physicochemical properties and mass concentration of organic aerosols (OA), but it is typically omitted by air quality, weather, and climate models. We compare two classes of simplified models to estimate the OA wat
Externí odkaz:
https://doaj.org/article/b2be4757100c438ba38a7ab6f2530951
Autor:
Sarah E. Cummings, Sean P. Delaney, Frederic St-Denis Bissonnette, Andrew Stalker, Gauri Muradia, Jelica Mehic, Tyson E. Graber, Tommy Alain, Jessie R. Lavoie
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108708- (2024)
Summary: Extracellular vesicles (EVs) are entering the clinical arena as novel biologics for infectious diseases, potentially serving as the immunogenic components of next generation vaccines. However, relevant human assays to evaluate the immunogeni
Externí odkaz:
https://doaj.org/article/46998e4c994a4f13a53d86c66f5bea2f
Autor:
Frederic St‐Denis‐Bissonnette, Sarah E. Cummings, Shirley Qiu, Andrew Stalker, Gauri Muradia, Jelica Mehic, Karan Mediratta, Shelby Kaczmarek, Dylan Burger, Seung‐Hwan Lee, Lisheng Wang, Jessie R. Lavoie
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Natural killer cell‐derived extracellular vesicles (NK‐EVs) have shown promising potential as biotherapeutics for cancer due to their unique attributes as cytotoxic nanovesicles against cancer cells and immune‐modulatory activity towar
Externí odkaz:
https://doaj.org/article/1906ed4190454e6db53b02b8e2e4579a
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011795 (2023)
Burkholderia pseudomallei is the causative agent of melioidosis, which is increasingly being reported worldwide. Mortality rates as high as 40% have been reported based on clinical patient outcomes in the endemic areas of Australia and Thailand. Nove
Externí odkaz:
https://doaj.org/article/507864f1f55e4eee9340ff09864717bb
Autor:
Margaret A. Redick, Milo E. Cummings, George F. Neuhaus, Lila M. Ardor Bellucci, Andrew R. Thurber, Kerry L. McPhail
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Deep-sea methane seeps host highly diverse microbial communities whose biological diversity is distinct from other marine habitats. Coupled with microbial community analysis, untargeted metabolomics of environmental samples using high resolution tand
Externí odkaz:
https://doaj.org/article/a9b66c2d48294754a7d25245256f9327
Autor:
Kaitlyn Tate, Rachel Ma, R. Colin Reid, Patrick McLane, Jen Waywitka, Garnet E. Cummings, Greta G. Cummings
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Documentation during resident transitions from long-term care (LTC) to the emergency department (ED) can be inconsistent, leading to inappropriate care. Inconsistent documentation can lead to undertreatment, inefficiencies and adv
Externí odkaz:
https://doaj.org/article/37eb06dcdfc04091aeab3483054b7ea4