MEF2C Directly Interacts with Pre-miRNAs and Distinct RNPs to Post-Transcriptionally Regulate miR-23a-miR-27a-miR-24-2 microRNA Cluster Member Expression

Autor: Estefanía Lozano-Velasco, Carlos Garcia-Padilla, Miguel Carmona-Garcia, Alba Gonzalez-Diaz, Angela Arequipa-Rendon, Amelia E. Aranega, Diego Franco

Publikováno v: Non-Coding RNA, Vol 10, Iss 3, p 32 (2024)

Transcriptional regulation constitutes a key step in gene expression regulation. Myocyte enhancer factor 2C (MEF2C) is a transcription factor of the MADS box family involved in the early development of several cell types, including muscle cells. Over

Externí odkaz: https://doaj.org/article/0fe5f4832fdf497bba19bfcf69615286

More than Just a Simple Cardiac Envelope; Cellular Contributions of the Epicardium

Autor: Diego Franco, Angel Dueñas, Amelia E. Aranega

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 5 (2017)

The adult pumping heart is formed by distinct tissue layers. From inside to outside, the heart is composed by an internal endothelial layer, dubbed the endocardium, a thick myocardial component which supports the pumping capacity of the heart and ext

Externí odkaz: https://doaj.org/article/cb3a802f9d4845f99cf61c5441797ac9

Post-Transcriptional Regulation of Molecular Determinants during Cardiogenesis

Autor: Estefania Lozano-Velasco, Carlos Garcia-Padilla, Maria del Mar Muñoz-Gallardo, Francisco Jose Martinez-Amaro, Sheila Caño-Carrillo, Juan Manuel Castillo-Casas, Cristina Sanchez-Fernandez, Amelia E. Aranega, Diego Franco

Publikováno v: International Journal of Molecular Sciences. 23:2839

Cardiovascular development is initiated soon after gastrulation as bilateral precardiac mesoderm is progressively symmetrically determined at both sides of the developing embryo. The precardiac mesoderm subsequently fused at the embryonic midline con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096b1d8890a724d35d4fd8751c51e533
https://doi.org/10.3390/ijms23052839

Oral abstract presentations

Autor: S. M. Davidson, M. M. Duchen, D. M. Yellon, L. Fields, M. Zaccolo, H. Laeremans, E. P. Daskalopoulos, B. J. A. Janssen, W. M. Blankesteijn, J. Tillmanns, D. Hoffmann, Y. Habbaba, D. Fraccarollo, P. Galuppo, J. Bauersachs, S. Novella, G. Segarra, A. P. Dantas, C. Bueno-Beti, L. Novensa, M. Lazaro-Franco, N. Martinez-Gil, P. Medina, C. Hermenegildo, J. Ohanian, A. Liao, A. W. Trafford, V. Ohanian, A. Perez-Moreno, P. Garcia-Canadilla, J. M. Dominguez, F. Crispi, E. Gratacos, I. Amat-Roldan, A. Gotschy, V. Herold, E. Bauer, C. Schrodt, G. Lykowsky, E. Rommel, P. Jakob, W. Bauer, M. Shah, M. B. Sikkel, T. Desplantez, T. P. Collins, P. O'Gara, S. E. Harding, A. R. Lyon, K. T. Macleod, C. Ferrantini, L. Sacconi, I. Lotti, R. Coppini, C. Tesi, P. Yan, L. M. Loew, E. Cerbai, C. Poggesi, F. S. Pavone, D. Franco, H. Daimi, J. N. Dominguez, L. Hove-Madsen, J. Cinca, E. Vazquez, A. E. Aranega, K. L. Poon, B. C. Kirchmaier, T. Schwerte, J. Huisken, C. Winkler, B. C. Jungblut, D. Y. Stainier, T. Brand, D. J. Stuckey, J. L. Tremoleda, S. Mcsweeney, L. Fiedler, M. Harada, C. A. Carr, D. J. Tyler, W. Gsell, K. Clarke, M. D. Schneider, V. Sequeira, J. A. Regan, M. Michels, F. J. Ten Cate, M. A. Van Slegtenhorst, G. J. M. Stienen, C. Dos Remedios, J. Van Der Velden

Publikováno v: Cardiovascular Research. 93:S88-S91

cAMP generated in response to β-adrenoceptor stimulation modulates excitation-contraction coupling via activation of PKA. It is now widely accepted that cAMP signalling is compartmentalised in the heart and that PDEs, the only cAMP degrading enzyme,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::807edb2036f584c76dbd0d67d5678805
https://doi.org/10.1093/cvr/cvr335

Modulation of cardiac intermediate filament proteins in the chick heart by fibric acid derivatives

Autor: A E, Aranega, M C, Velez, F J, Gonzalez, C, Melguizo, J C, Prados, A, Aranega

Publikováno v: European journal of morphology. 33(5)

The effects of different fibrates (bezafibrate, fenofibrate and gemfibrozil) on intermediate filaments were studied in cultured chick embryo heart cells after treatment for 6 or 24 h. Treatment led to alterations in total protein levels, as well as c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08265c8c595fd0eb713ca9ee5f02cdf3
https://pubmed.ncbi.nlm.nih.gov/8907555