Zobrazeno 1 - 10
of 111
pro vyhledávání: '"A. E. Ansell"'
Autor:
Alexander D. Walsh, Sarrabeth Stone, Saskia Freytag, Andrea Aprico, Trevor J. Kilpatrick, Brendan R. E. Ansell, Michele D. Binder
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Microglia regulate multiple processes in the central nervous system, exhibiting a considerable level of cellular plasticity which is facilitated by an equally dynamic transcriptional environment. While many gene networks that regulate microg
Externí odkaz:
https://doaj.org/article/38de1b89c4074016a7cfc2ccfcc14aef
Autor:
Kevin T. Eade, Brendan Robert E. Ansell, Sarah Giles, Regis Fallon, Sarah Harkins-Perry, Takayuki Nagasaki, Simone Tzaridis, Martina Wallace, Elizabeth A. Mills, Samaneh Farashi, Alec Johnson, Lydia Sauer, Barbara Hart, M. Elena Diaz-Rubio, Melanie Bahlo, Christian Metallo, Rando Allikmets, Marin L. Gantner, Paul S. Bernstein, Martin Friedlander
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Patient-derived induced pluripotent stem cells (iPSCs) provide a powerful tool for identifying cellular and molecular mechanisms of disease. Macular telangiectasia type 2 (MacTel) is a rare, late-onset degenerative retinal disease with an extremely h
Externí odkaz:
https://doaj.org/article/c36953378fea49618ef3b23be50c87cb
Autor:
Roberto Bonelli, Brendan R. E. Ansell, Luca Lotta, Thomas Scerri, Traci E. Clemons, Irene Leung, The MacTel Consortium, Tunde Peto, Alan C. Bird, Ferenc B. Sallo, Claudia Langenberg, Melanie Bahlo
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background Macular telangiectasia type 2 (MacTel) is a rare, heritable and largely untreatable retinal disorder, often comorbid with diabetes. Genetic risk loci subtend retinal vascular calibre and glycine/serine/threonine metabolism genes.
Externí odkaz:
https://doaj.org/article/8032d5f734e6454196e3e20390376c09
Autor:
Roberto Bonelli, Victoria E. Jackson, Aravind Prasad, Jacob E. Munro, Samaneh Farashi, Tjebo F. C. Heeren, Nikolas Pontikos, Lea Scheppke, Martin Friedlander, MacTel Consortium, Catherine A. Egan, Rando Allikmets, Brendan R. E. Ansell, Melanie Bahlo
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Melanie Bahlo and colleagues report a genome-wide association study on the retinal degenerative disease Macular Telangiectasia Type 2, identifying 8 new genome-wide significant loci. Further analyses suggest key roles for genes that transport and syn
Externí odkaz:
https://doaj.org/article/9cba7a84572b4acc832cac9a6d05482a
Autor:
Alexander C. Perino, Peter Shrader, Mintu P. Turakhia, Jack E. Ansell, Bernard J. Gersh, Gregg C. Fonarow, Alan S. Go, Daniel W. Kaiser, Elaine M. Hylek, Peter R. Kowey, Daniel E. Singer, Laine Thomas, Benjamin A. Steinberg, Eric D. Peterson, Jonathan P. Piccini, Kenneth W. Mahaffey
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 9 (2019)
Background Patient satisfaction with therapy is an important metric of care quality and has been associated with greater medication persistence. We evaluated the association of patient satisfaction with warfarin therapy to other metrics of anticoagul
Externí odkaz:
https://doaj.org/article/3f5c0c4632c64617860042a4d7d61964
Autor:
Hannah F. Norton, Margaret E. Ansell, Ariel Pomputius, Mary E. Edwards, Matthew Daley, Susan Harnett
Publikováno v:
Journal of the Medical Library Association, Vol 107, Iss 2 (2019)
Background: While rates of new HIV diagnoses have gone down nationally, Florida’s HIV-positive population is growing and remains one of the largest in the country. Given this landscape, it is clear that diverse, creative, and collaborative efforts
Externí odkaz:
https://doaj.org/article/6f02bcd4538a4a5185553a231f0ed4c2
Autor:
Roberto Bonelli, Victoria E. Jackson, Aravind Prasad, Jacob E. Munro, Samaneh Farashi, Tjebo F. C. Heeren, Nikolas Pontikos, Lea Scheppke, Martin Friedlander, MacTel Consortium, Catherine A. Egan, Rando Allikmets, Brendan R. E. Ansell, Melanie Bahlo
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01972-y
Externí odkaz:
https://doaj.org/article/8e9e260332a94a1b9593ace90158e3ba
Autor:
Roberto Bonelli, Sasha M. Woods, Sarah Lockwood, Paul N. Bishop, Kamron N. Khan, Melanie Bahlo, Brendan R. E. Ansell, Marcus Fruttiger
Publikováno v:
Metabolomics. 19
Introduction The primate retina has evolved regional specialisations for specific visual functions. The macula is specialised towards high acuity vision and is an area that contains an increased density of cone photoreceptors and signal processing ne
Autor:
Jeffrey B. Washam, DaJuanicia N. Holmes, Laine E. Thomas, Sean D. Pokorney, Elaine M. Hylek, Gregg C. Fonarow, Kenneth W. Mahaffey, Bernard J. Gersh, Peter R. Kowey, Jack E. Ansell, Alan S. Go, James A. Reiffel, James V. Freeman, Daniel E. Singer, Gerald Naccarelli, Rosalia Blanco, Eric D. Peterson, Jonathan P. Piccini
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 18 (2018)
Background Chronic kidney disease (CKD) is a common comorbidity in patients with atrial fibrillation. The presence of CKD complicates drug selection for stroke prevention and rhythm control. Methods and Results Patients enrolled in ORBIT AF (Outcomes
Externí odkaz:
https://doaj.org/article/0ef1abfb713f46d0b6b200b18ab7877d
Autor:
Showgy Y. Ma'ayeh, Livia Knörr, Karin Sköld, Alexandra Garnham, Brendan R. E. Ansell, Aaron R. Jex, Staffan G. Svärd
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Externí odkaz:
https://doaj.org/article/47cc7dc1c30b4e63be8f095e4a549fae