Zobrazeno 1 - 10
of 122
pro vyhledávání: '"A. Douglas Laird"'
Autor:
Nicholas C. Turner, A. Douglas Laird, Melinda L. Telli, Hope S. Rugo, Audrey Mailliez, Johannes Ettl, Eva-Maria Grischke, Lida A. Mina, Judith Balmaña, Peter A. Fasching, Sara A. Hurvitz, Julia F. Hopkins, Lee A. Albacker, Jijumon Chelliserry, Ying Chen, Umberto Conte, Andrew M. Wardley, Mark E. Robson
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract These analyses explore the impact of homologous recombination repair gene mutations, including BRCA1/2 mutations and homologous recombination deficiency (HRD), on the efficacy of the poly(ADP-ribose) polymerase (PARP) inhibitor talazoparib i
Externí odkaz:
https://doaj.org/article/38e11546389a453baf13464d8594cd8f
Autor:
Daniel J. DeAngelo, Wendy Stock, Anthony S. Stein, Andrei Shustov, Michaela Liedtke, Charles A. Schiffer, Erik Vandendries, Katherine Liau, Revathi Ananthakrishnan, Joseph Boni, A. Douglas Laird, Luke Fostvedt, Hagop M. Kantarjian, Anjali S. Advani
Publikováno v:
Blood Advances, Vol 1, Iss 15, Pp 1167-1180 (2017)
Abstract: This study evaluated the safety, antitumor activity, pharmacokinetics, and pharmacodynamics of inotuzumab ozogamicin (InO) for CD22-positive relapsed/refractory acute lymphoblastic leukemia. In phase 1, patients received InO 1.2 (n = 3), 1.
Externí odkaz:
https://doaj.org/article/75e7d5b654074258b13162642cc5791e
Autor:
Mylène Ratelle, Andrew Spring, Brian Douglas Laird, Leon Andrew, Deborah Simmons, Alexa Scully, Kelly Skinner
Publikováno v:
FACETS, Vol 7, Iss , Pp 343-359 (2022)
Resource development and climate change are increasing concerns regarding safe water for Indigenous people in Canada. A research study was completed to characterize the consumption of water and beverages prepared with water and identify the perceptio
Externí odkaz:
https://doaj.org/article/0cbb26c80abc46a7afa65347c75e2751
Autor:
Julia Gyapay, Kanelsa Noksana, Sonja Ostertag, Sonia Wesche, Brian Douglas Laird, Kelly Skinner
Publikováno v:
Nutrients, Vol 14, Iss 9, p 1915 (2022)
Northern Indigenous communities require collaborative approaches to health communication about food that are grounded in Indigenous knowledges and cultures; however, preferences and best methods for this process remain understudied. This participator
Externí odkaz:
https://doaj.org/article/e5cf738f03f148ae828f5b3c36ae1f07
Publikováno v:
Nutrients, Vol 14, Iss 2, p 378 (2022)
A dietary transition away from traditional foods and toward a diet of the predominantly unhealthy market is a public health and sociocultural concern throughout Indigenous communities in Canada, including those in the sub-Arctic and remote regions of
Externí odkaz:
https://doaj.org/article/3ce8bd01a36c4fa79082d224a1f504f0
Autor:
Shunsuke Kimura, Lindsey Montefiori, Ilaria Iacobucci, Yaqi Zhao, Qingsong Gao, Elisabeth M. Paietta, Claudia Haferlach, A. Douglas Laird, Paul E. Mead, Zhaohui Gu, Wendy Stock, Mark Litzow, Jacob M. Rowe, Selina M. Luger, Stephen P. Hunger, Georgina L. Ryland, Breon Schmidt, Paul G. Ekert, Alicia Oshlack, Sean M. Grimmond, Jacqueline Rehn, James Breen, David Yeung, Deborah L. White, Ibrahim Aldoss, Elias J. Jabbour, Ching-Hon Pui, Manja Meggendorfer, Wencke Walter, Wolfgang Kern, Torsten Haferlach, Samuel Brady, Jinghui Zhang, Kathryn G. Roberts, Piers Blombery, Charles G. Mullighan
Publikováno v:
Blood
Transcriptome sequencing has identified multiple subtypes of B-progenitor acute lymphoblastic leukemia (B-ALL) of prognostic significance, but a minority of cases lack a known genetic driver. Here, we used integrated whole-genome (WGS) and -transcrip
Autor:
Ilaria Iacobucci, Reiji Fukano, Jake D. Friske, Chunxu Qu, Laura J. Janke, Yaqi Zhao, Pradyuamna Baviskar, Emily A. Backhaus, Peter Chockley, Aman Seth, A. Douglas Laird, Anjali S. Advani, Charles G. Mullighan
Publikováno v:
Blood Advances. 6:3255-3259
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Dose-response relationships for inhibition of PI3K pathway signaling by XL147 in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260634cb87fb5d622eb4168f46e64fc0
https://doi.org/10.1158/1535-7163.22501281.v1
https://doi.org/10.1158/1535-7163.22501281.v1
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Effects of XL147 on PI3K Signaling Pathway in OVCAR-3 and U87-MG cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f71be1beb32a7e6d834de7d7f0c096d
https://doi.org/10.1158/1535-7163.22501287.v1
https://doi.org/10.1158/1535-7163.22501287.v1
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Effects of XL147 on PI3K Signaling Pathway in EGF-Stimulated PC-3 Cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9669a150af5e5be12d3299122d031454
https://doi.org/10.1158/1535-7163.22501293.v1
https://doi.org/10.1158/1535-7163.22501293.v1