Zobrazeno 1 - 10
of 1 696
pro vyhledávání: '"A. Dobrovic"'
Autor:
Ksenija Nesic, John J. Krais, Yifan Wang, Cassandra J. Vandenberg, Pooja Patel, Kathy Q. Cai, Tanya Kwan, Elizabeth Lieschke, Gwo-Yaw Ho, Holly E. Barker, Justin Bedo, Silvia Casadei, Andrew Farrell, Marc Radke, Kristy Shield-Artin, Jocelyn S. Penington, Franziska Geissler, Elizabeth Kyran, Robert Betsch, Lijun Xu, Fan Zhang, Alexander Dobrovic, Inger Olesen, Rebecca Kristeleit, Amit Oza, Iain McNeish, Gayanie Ratnayake, Nadia Traficante, Australian Ovarian Cancer Study, Anna DeFazio, David D. L. Bowtell, Thomas C. Harding, Kevin Lin, Elizabeth M. Swisher, Olga Kondrashova, Clare L. Scott, Neil Johnson, Matthew J. Wakefield
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract PARP inhibitor (PARPi) therapy has transformed outcomes for patients with homologous recombination DNA repair (HRR) deficient ovarian cancers, for example those with BRCA1 or BRCA2 gene defects. Unfortunately, PARPi resistance is common. Mul
Externí odkaz:
https://doaj.org/article/8f0a9b712db94dd79db01d43d570add9
Autor:
Irina Pristas, Josip Ujevic, Kristian Bodulić, Natasa Andrijasevic, Branka Bedenic, Marina Payerl-Pal, Edita Susic, Karolina Dobrovic, Sien De Koster, Surbhi Malhotra-Kumar, Arjana Tambic Andrasevic
Publikováno v:
Microorganisms, Vol 12, Iss 10, p 1997 (2024)
Klebsiella pneumoniae is an opportunistic pathogen known for two main pathotypes: classical K. pneumoniae (cKp), often multidrug-resistant and common in hospitals, and hypervirulent K. pneumoniae (hvKp), associated with severe community-acquired infe
Externí odkaz:
https://doaj.org/article/84e90a221d1b4537b98f4aaf3fddb5b4
Landscape of microalgae omics and metabolic engineering research for strain improvement: An overview
Autor:
Stavridou, Evangelia, Karapetsi, Lefkothea, Nteve, Georgia Maria, Tsintzou, Georgia, Chatzikonstantinou, Marianna, Tsaousi, Meropi, Martinez, Angel, Flores, Pablo, Merino, Marián, Dobrovic, Luka, Mullor, José Luis, Martens, Stefan, Cerasino, Leonardo, Salmaso, Nico, Osathanunkul, Maslin, Labrou, Nikolaos E., Madesis, Panagiotis
Publikováno v:
In Aquaculture 30 June 2024 587
Autor:
Jihoon E. Joo, Khalid Mahmood, Romy Walker, Peter Georgeson, Ida Candiloro, Mark Clendenning, Julia Como, Sharelle Joseland, Susan Preston, Lise Graversen, Mathilda Wilding, Michael Field, Michelle Lemon, Janette Wakeling, Helen Marfan, Rachel Susman, Joanne Isbister, Emma Edwards, Michelle Bowman, Judy Kirk, Emilia Ip, Lynne McKay, Yoland Antill, John L. Hopper, Alex Boussioutas, Finlay A. Macrae, Alexander Dobrovic, Mark A. Jenkins, Christophe Rosty, Ingrid M. Winship, Daniel D. Buchanan
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-17 (2023)
Abstract Background MLH1 epimutation is characterised by constitutional monoallelic MLH1 promoter hypermethylation, which can cause colorectal cancer (CRC). Tumour molecular profiles of MLH1 epimutation CRCs were used to classify germline MLH1 promot
Externí odkaz:
https://doaj.org/article/205aa9e2d6d045aca7e0fc588c972c5c
Autor:
Franziska Geissler, Ksenija Nesic, Olga Kondrashova, Alexander Dobrovic, Elizabeth M. Swisher, Clare L. Scott, Matthew J. Wakefield
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Epigenetic alterations, including aberrant DNA methylation, are now recognized as bone fide hallmarks of cancer, which can contribute to cancer initiation, progression, therapy responses and therapy resistance. Methylation of gene promoters can have
Externí odkaz:
https://doaj.org/article/149fbe6f4eb449958647e023e6a32ed0
Autor:
Boštjančić, Ljudevit Luka, Francesconi, Caterina, Bonassin, Lena, Hudina, Sandra, Gračan, Romana, Maguire, Ivana, Rutz, Christelle, Beck, Ana, Dobrović, Ana, Lecompte, Odile, Theissinger, Kathrin
Publikováno v:
In Fish and Shellfish Immunology December 2023 143
Autor:
Genevieve Dall, Cassandra J. Vandenberg, Ksenija Nesic, Gayanie Ratnayake, Wenying Zhu, Joseph H. A. Vissers, Justin Bedő, Jocelyn Penington, Matthew J. Wakefield, Damien Kee, Amandine Carmagnac, Ratana Lim, Kristy Shield-Artin, Briony Milesi, Amanda Lobley, Elizabeth L. Kyran, Emily O’Grady, Joshua Tram, Warren Zhou, Devindee Nugawela, Kym Pham Stewart, Reece Caldwell, Lia Papadopoulos, Ashley P. Ng, Alexander Dobrovic, Stephen B. Fox, Orla McNally, Jeremy D. Power, Tarek Meniawy, Teng Han Tan, Ian M. Collins, Oliver Klein, Stephen Barnett, Inger Olesen, Anne Hamilton, Oliver Hofmann, Sean Grimmond, Anthony T. Papenfuss, Clare L. Scott, Holly E. Barker
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background Uterine leiomyosarcoma (uLMS) is a rare and aggressive gynaecological malignancy, with individuals with advanced uLMS having a five-year survival of 0.2) but only two samples had a CHORD score > 50%, one of which had a homozygous
Externí odkaz:
https://doaj.org/article/90697e9e0fe04ca583a35a4167337ba8
Autor:
Daniel R A Cox, William Chung, Josephine Grace, Darren Wong, Numan Kutaiba, Dinesh Ranatunga, Richard Khor, Marcos V Perini, Michael Fink, Robert Jones, Mark Goodwin, Alex Dobrovic, Adam Testro, Vijayaragavan Muralidharan
Publikováno v:
JGH Open, Vol 7, Iss 4, Pp 249-260 (2023)
Abstract Hepatocellular carcinoma (HCC) is an aggressive primary malignancy of the liver and is the third most common cause of cancer‐related global mortality. There has been a steady increase in treatment options for HCC in recent years, including
Externí odkaz:
https://doaj.org/article/5b783e2327914303b4b3d22c5e2e2928
Autor:
Gwo Yaw Ho, Cassandra J. Vandenberg, Ratana Lim, Elizabeth L. Christie, Dale W. Garsed, Elizabeth Lieschke, Ksenija Nesic, Olga Kondrashova, Gayanie Ratnayake, Marc Radke, Jocelyn S. Penington, Amandine Carmagnac, Valerie Heong, Elizabeth L. Kyran, Fan Zhang, Nadia Traficante, Ruby Huang, Alexander Dobrovic, Elizabeth M. Swisher, Orla McNally, Damien Kee, Matthew J. Wakefield, Anthony T. Papenfuss, David D. L. Bowtell, Holly E. Barker, Clare L. Scott
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Despite initial response to platinum-based chemotherapy and PARP inhibitor therapy (PARPi), nearly all recurrent high-grade serous ovarian cancer (HGSC) will acquire lethal drug resistance; indeed, ~15% of individuals have de novo platinu
Externí odkaz:
https://doaj.org/article/acfd52763fdb4a6092abd9806478e071
Autor:
Daniel RA Cox, Boris Ka Leong Wong, Eunice Lee, Adam Testro, Vijayaragavan Muralidharan, Alexander Dobrovic, Su Kah Goh
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 1956-1960 (2022)
The detection of methylated templates in cell-free DNA (cfDNA) is increasingly recognized as a valuable, non-invasive tool for diagnosis, monitoring and prognostication in a range of medical contexts. The importance of controlling pre-analytical cond
Externí odkaz:
https://doaj.org/article/302e82ba934d49aca4424702599ea6d5