Zobrazeno 1 - 10
of 164
pro vyhledávání: '"A. Di Gregoli"'
Autor:
Di Gregoli, Karina1 (AUTHOR) karina.digregoli@gmail.com, Atkinson, Georgia1 (AUTHOR), Williams, Helen1 (AUTHOR), George, Sarah J.1 (AUTHOR), Johnson, Jason L.1 (AUTHOR) jason.l.johnson@bristol.ac.uk
Publikováno v:
International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p5809. 18p.
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Abdominal aortic aneurysms (AAAs) account for up to 8% of deaths in men aged 65 years and over and 2.2% of women. Patients with AAAs often have atherosclerosis, and intimal atherosclerosis is generally present in AAAs. Accordingly, AAAs are considere
Externí odkaz:
https://doaj.org/article/04a1a382ce59481da1c61714e2f4ba52
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100108- (2020)
Summary: Aortic aneurysm rupture is a significant cause of premature mortality worldwide. Although animal models exist, some frequently experience aortic rupture and sudden death. An alternative approach is therefore required that would use human mat
Externí odkaz:
https://doaj.org/article/4043a8657b8b485d84825b4fa9e0f052
Akademický článek
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Autor:
Nur Syahidah Nor Hisam, Azizah Ugusman, Nor Fadilah Rajab, Karina Di Gregoli, Mohd Faizal Ahmad, Nur Najmi Mohamad Anuar
Navitoclax is an effective pro-apoptotic agent against cancer cells. Uncontrolled cell survival is a hallmark of pathological angiogenesis in cancer and could promote plaque instability that contributes to atherosclerosis progression owing to intrapl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4192a6f53f2843bba8b613109e1ab618
https://doi.org/10.21203/rs.3.rs-2759691/v1
https://doi.org/10.21203/rs.3.rs-2759691/v1
Autor:
Aleksandra Frankow, Andrew C. Newby, Jason L. Johnson, Christopher L. Jackson, Sarah J George, Karina Di Gregoli, Rosaria Bianco, Michelle Somerville, Aniita C. Thomas
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Galectin-3 (formerly known as Mac-2), encoded by the LGALS3 gene, is proposed to regulate macrophage adhesion, chemotaxis, and apoptosis. We investigated the role of galectin-3 in
Objective: Galectin-3 (formerly known as Mac-2), encoded by the LGALS3 gene, is proposed to regulate macrophage adhesion, chemotaxis, and apoptosis. We investigated the role of galectin-3 in
Akademický článek
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Autor:
Aikaterini Tsaousi, Elaine M Hayes, Karina Di Gregoli, Andrew R Bond, Laura Bevan, Anita C Thomas, Andrew C Newby
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148873 (2016)
BACKGROUND:Thelper1 (Th1) lymphocytes have been previously implicated in atherosclerotic plaque growth but their role in plaque vulnerability to rupture is less clear. We investigated whether T-bet knockout that prevents Th1 lymphocyte differentiatio
Externí odkaz:
https://doaj.org/article/55f6eff7c91b40f5b0acfdfc775ade44
Autor:
Jason L. Johnson, Nicholas P. Jenkins, Wei-Chun Huang, Karina Di Gregoli, Graciela B. Sala-Newby, Vincent P. W. Scholtes, Frans L. Moll, Gerard Pasterkamp, Andrew C. Newby
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Matrix metalloproteinase-14 (MMP-14) promotes vulnerable plaque morphology in mice, whereas tissue inhibitor of metalloproteinases-3 (TIMP-3) overexpression is protective. MMP-14hi TIMP-3lo rabbit foam cells are more invasive and more prone to apopto
Externí odkaz:
https://doaj.org/article/b700e525ba45472391bf6493c4185e94
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100108-(2020)
Bianco, R, Di Gregoli, K, Caputo, M, George, S J & Johnson, J L 2020, ' A Protocol for a Novel Human Ex Vivo Model of Aneurysm ', STAR Protocols, vol. 1, no. 3, pp. 100108 . https://doi.org/10.1016/j.xpro.2020.100108
Bianco, R, Di Gregoli, K, Caputo, M, George, S J & Johnson, J L 2020, ' A Protocol for a Novel Human Ex Vivo Model of Aneurysm ', STAR Protocols, vol. 1, no. 3, pp. 100108 . https://doi.org/10.1016/j.xpro.2020.100108
Summary Aortic aneurysm rupture is a significant cause of premature mortality worldwide. Although animal models exist, some frequently experience aortic rupture and sudden death. An alternative approach is therefore required that would use human mate