Zobrazeno 1 - 10
of 231
pro vyhledávání: '"A. Dessa Sadovnick"'
Autor:
Mariya V. Cherkasova, Jessie F. Fu, Michael Jarrett, Poljanka Johnson, Shawna Abel, Roger Tam, Alexander Rauscher, Vesna Sossi, Shannon Kolind, David K. B. Li, A. Dessa Sadovnick, Lindsay Machan, J. Marc Girard, Francois Emond, Reza Vosoughi, Anthony Traboulsee, A. Jon Stoessl
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Despite significant insights into the neural mechanisms of acute placebo responses, less is known about longer-term placebo responses, such as those seen in clinical trials, or their interactions with brain disease. We examined brain correla
Externí odkaz:
https://doaj.org/article/30c8b9aed02c4603971a3aaa47f1c6d6
Autor:
Elia Gil-Varea, Elena Urcelay, Carles Vilariño-Güell, Carme Costa, Luciana Midaglia, Fuencisla Matesanz, Alfredo Rodríguez-Antigüedad, Jorge Oksenberg, Laura Espino-Paisan, A. Dessa Sadovnick, Albert Saiz, Luisa M. Villar, Juan Antonio García-Merino, Lluís Ramió-Torrentà, Juan Carlos Triviño, Ester Quintana, René Robles, Antonio Sánchez-López, Rafael Arroyo, Jose C. Alvarez-Cermeño, Angela Vidal-Jordana, Sunny Malhotra, Nicolas Fissolo, Xavier Montalban, Manuel Comabella
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Background It remains unclear whether disease course in multiple sclerosis (MS) is influenced by genetic polymorphisms. Here, we aimed to identify genetic variants associated with benign and aggressive disease courses in MS patients. Methods
Externí odkaz:
https://doaj.org/article/833c0146c0374957a77d4180572e95c7
Autor:
A. Dessa Sadovnick, Anthony L. Traboulsee, Cecily Q. Bernales, Jay P. Ross, Amanda L. Forwell, Irene M. Yee, Lena Guillot-Noel, Bertrand Fontaine, Isabelle Cournu-Rebeix, Antonio Alcina, Maria Fedetz, Guillermo Izquierdo, Fuencisla Matesanz, Kelly Hilven, Bénédicte Dubois, An Goris, Ianire Astobiza, Iraide Alloza, Alfredo Antigüedad, Koen Vandenbroeck, Denis A. Akkad, Orhan Aktas, Paul Blaschke, Mathias Buttmann, Andrew Chan, Joerg T. Epplen, Lisa-Ann Gerdes, Antje Kroner, Christian Kubisch, Tania Kümpfel, Peter Lohse, Peter Rieckmann, Uwe K. Zettl, Frauke Zipp, Lars Bertram, Christina M Lill, Oscar Fernandez, Patricia Urbaneja, Laura Leyva, Jose Carlos Alvarez-Cermeño, Rafael Arroyo, Aroa M. Garagorri, Angel García-Martínez, Luisa M. Villar, Elena Urcelay, Sunny Malhotra, Xavier Montalban, Manuel Comabella, Thomas Berger, Franz Fazekas, Markus Reindl, Mascha C. Schmied, Alexander Zimprich, Carles Vilariño-Güell
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 7, Pp 2073-2079 (2016)
Multiple sclerosis (MS) is a prevalent neurological disease of complex etiology. Here, we describe the characterization of a multi-incident MS family that nominated a rare missense variant (p.G420D) in plasminogen (PLG) as a putative genetic risk fac
Externí odkaz:
https://doaj.org/article/ad94b930f9574b93ac8b8955b0887d3c
Autor:
Geoffrey Paltser, Xue Jun Liu, Jason Yantha, Shawn Winer, Hubert Tsui, Ping Wu, Yuko Maezawa, Lindsay S. Cahill, Christine L. Laliberté, Sreeram V. Ramagopalan, Gabriele C. DeLuca, A. Dessa Sadovnick, Igor Astsaturov, George C. Ebers, R. Mark Henkelman, Michael W. Salter, H.-Michael Dosch
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 149-159 (2013)
Abstract Multiple sclerosis (MS) is a chronic progressive, demyelinating condition whose therapeutic needs are unmet, and whose pathoetiology is elusive. We report that transient receptor potential vanilloid-1 (TRPV1) expressed in a major sensory neu
Externí odkaz:
https://doaj.org/article/e5890ad622bf4df7ba2d1d634ebcb2de
Autor:
Federica Esposito, Ana Maria Osiceanu, Melissa Sorosina, Linda Ottoboni, Bryan Bollman, Silvia Santoro, Barbara Bettegazzi, Andrea Zauli, Ferdinando Clarelli, Elisabetta Mascia, Andrea Calabria, Daniele Zacchetti, Ruggero Capra, Maurizio Ferrari, Paolo Provero, Dejan Lazarevic, Davide Cittaro, Paola Carrera, Nikolaos Patsopoulos, Daniela Toniolo, A Dessa Sadovnick, Gianvito Martino, Philip L. De Jager, Giancarlo Comi, Elia Stupka, Carles Vilariño-Güell, Laura Piccio, Filippo Martinelli Boneschi
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2392
While the role of common genetic variants in multiple sclerosis (MS) has been elucidated in large genome-wide association studies, the contribution of rare variants to the disease remains unclear. Herein, a whole-genome sequencing study in four affec
Autor:
Annika Anderson, William Rowles, Kira Mcpolin, Kristen M. Krysko, Alice Rutatangwa, Jessica Singh, Maria K. Houtchens, A. Dessa Sadovnick, Riley Bove
Publikováno v:
Multiple Sclerosis Journal. 28:970-979
Background: Peripartum depression (PPD) is underexplored in multiple sclerosis (MS). Objective: To evaluate prevalence of and risk factors for PPD in women with MS. Methods: Retrospective single-center analysis of women with MS with a live birth. Pre
Autor:
Bridget LaMonica Ostrem, Annika Anderson, Sarah Conway, Brian C Healy, Jiwon Oh, Dina Jacobs, Ruth Dobson, Edith Larmon Graham, A Dessa Sadovnick, Vanessa Zimmerman, Yanqing Liu, Riley Bove, Maria Houtchens
Publikováno v:
Multiple sclerosis journal-experimental, translational and clinical, vol 8, iss 2
Background The effects of pregnancy on multiple sclerosis (MS) inflammatory activity are not well described in women with moderate to severe disabilities. Objective To quantify the peripartum annualized relapse rate (ARR) in women with MS with an Exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8097f1b79441c190d30f4a49cef62ec1
https://escholarship.org/uc/item/66v2t693
https://escholarship.org/uc/item/66v2t693
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 47:109-114
Multiple sclerosis (MS) is the most common cause of neurological disability, other than trauma, among young adults of reproductive age. In contrast to the past, today there is very little lag time from clinical onset to diagnosis. Disease-modifying t
Publikováno v:
Multiple Sclerosis Journal-Experimental, Translational and Clinical
Objective The objective of this prospective “real world” study is to gain insight into the different “roads to conception” that women with MS take as part of the prospective Canadian Multiple Sclerosis Pregnancy Study (CANPREG-MS). Methods Pa
Autor:
Jacqueline A. Quandt, Cecily Q. Bernales, Carles Vilariño-Güell, A. Dessa Sadovnick, Mary Encarnacion, Anthony Traboulsee, Lisa F Popplewell
Publikováno v:
Immunogenetics. 72(6-7)
Genetic and functional analyses of the inflammasome suggest a role for this multiprotein complex in the biological mechanisms leading to the onset and progression of multiple sclerosis (MS). Nucleotide-binding, leucine-rich repeat (NLR) receptors tri