Zobrazeno 1 - 10
of 246
pro vyhledávání: '"A. D. Van Der Meer"'
Publikováno v:
Frontiers in Lab on a Chip Technologies, Vol 3 (2024)
Organs-on-chips (OoC) are in vitro models that emulate key functionalities of tissues or organs in a miniaturized and highly controlled manner. Due to their high versatility, OoC have evolved as promising alternatives to animal testing for a more eff
Externí odkaz:
https://doaj.org/article/5d468d7ba7aa4ae8b1744caf7a389e7a
Autor:
H. H. T. Middelkamp, A. H. A. Verboven, A. G. De Sá Vivas, C. Schoenmaker, T. M. Klein Gunnewiek, R. Passier, C. A. Albers, P. A. C. ‘t Hoen, N. Nadif Kasri, A. D. van der Meer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract In vitro neuronal models are essential for studying neurological physiology, disease mechanisms and potential treatments. Most in vitro models lack controlled vasculature, despite its necessity in brain physiology and disease. Organ-on-chip
Externí odkaz:
https://doaj.org/article/801201348ddd426a9c4934d59048c886
Publikováno v:
International Journal of Cell Biology, Vol 2009 (2009)
Vascular endothelial cells have an extensive response to physiological levels of shear stress. There is evidence that the protein caveolin-1 is involved in the early phase of this response. In this study, caveolin-1 was downregulated in human endothe
Externí odkaz:
https://doaj.org/article/f158e71f2d1443879004803ea5963740
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Cardiotoxicity, characterized by severe cardiac dysfunction, is a major problem in patients treated with different classes of anticancer drugs. Development of predictable human-based models and assays for drug screening are crucia
Externí odkaz:
https://doaj.org/article/8ff6dd0ccbc9453ebb43ce6543ef29f0
Autor:
Mees N. S. de Graaf, Aisen Vivas, Andries D. van der Meer, Christine L. Mummery, Valeria V. Orlova
Publikováno v:
Micromachines, Vol 13, Iss 8, p 1359 (2022)
Organ-on-chip (OoC) devices are increasingly used to mimic the tissue microenvironment of cells in intact organs. This includes microchannels to mimic, for example, fluidic flow through blood vessels. Present methods for controlling microfluidic flow
Externí odkaz:
https://doaj.org/article/0998b380767740f0bdcac4f5f3ff011e
Autor:
D. van der Meer, L. Chovet, A. Bera, A. Richard, Pedro Jesus Sánchez Cuevas, J. R. Sánchez-Ibáñez, M. Olivares-Mendez
Publikováno v:
Frontiers in Robotics and AI. 10
Space resource utilisation is opening a new space era. The scientific proof of the presence of water ice on the south pole of the Moon, the recent advances in oxygen extraction from lunar regolith, and its use as a material to build shelters are posi
Autor:
Mees N. S. de Graaf, Aisen Vivas, Dhanesh G. Kasi, Francijna E. van den Hil, Albert van den Berg, Andries D. van der Meer, Christine L. Mummery, Valeria V. Orlova
Publikováno v:
Lab on a chip, 23(1), 168-181. Royal Society of Chemistry
Lab on a Chip, 23(1), 168-181. ROYAL SOC CHEMISTRY
Lab on a Chip, 23(1), 168-181. ROYAL SOC CHEMISTRY
Three-dimensional (3D) blood vessels-on-a-chip (VoC) models integrate the biological complexity of vessel walls with dynamic microenvironmental cues, such as wall shear stress (WSS) and circumferential strain (CS). However, these parameters are diffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35dea81de8eb0e3c91d1de9d4846fd48
https://research.utwente.nl/en/publications/2a7eb61a-c021-4125-8d29-54bc82fbbef9
https://research.utwente.nl/en/publications/2a7eb61a-c021-4125-8d29-54bc82fbbef9
Autor:
E.P. Tissink, A.A. Shadrin, D. van der Meer, N. Parker, G. Hindley, D. Roelfs, O. Frei, C.C. Fan, M. Nagel, T. Nærland, M. Budisteanu, S. Djurovic, L. T. Westlye, M.P. van den Heuvel, D. Posthuma, T. Kaufmann, A.M. Dale, O.A. Andreassen
Genetic pleiotropy is abundant across spatially distributed brain characteristics derived from one neuroimaging modality (e.g. structural, functional or diffusion MRI). A better understanding of pleiotropy across modalities could inform us on the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66a036a2b05d58f70050300d106fec50
https://doi.org/10.1101/2022.12.20.521181
https://doi.org/10.1101/2022.12.20.521181
Publikováno v:
Planetary and space science, 223:105579. Elsevier
A technique for estimating clinoptilolite, montmorillonite, and epsomite mineral abundances from a reflectance spectrum of mineral mixtures using spectral deconvolution and a deep neural network is proposed. Sixty-six ternary mineral mixtures were ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1561284d9e33f0a4d6013ac53ff87fca
https://research.utwente.nl/en/publications/cb43b37e-8c31-420a-bde9-717d26e85f93
https://research.utwente.nl/en/publications/cb43b37e-8c31-420a-bde9-717d26e85f93
Publikováno v:
Geosystems and Geoenvironment. Elsevier
While non-analcime zeolites are plausible mineral constituents of the Martian surface, their lack of prominent spectral characteristics in the visible to shortwave infrared wavelength region makes them difficult to identify using orbital data. This l