Zobrazeno 1 - 10
of 24
pro vyhledávání: '"A. D. Kahle"'
Autor:
Sushanth Kumar, Sakar Budhathoki, Christopher B. Oliveira, August D. Kahle, O. Yipkin Calhan, John R. Lukens, Christopher D. Deppmann
Publikováno v:
JCI Insight, Vol 8, Iss 3 (2023)
The molecular mediators of cell death and inflammation in Alzheimer’s disease (AD) have yet to be fully elucidated. Caspase-8 is a critical regulator of several cell death and inflammatory pathways; however, its role in AD pathogenesis has not yet
Externí odkaz:
https://doaj.org/article/2d8e886527cc4f8c949f940257aa15b7
Publikováno v:
Mathematische Semesterberichte. 41:95-112
Publikováno v:
Biochimie. 75:955-962
Several phosphorothioate-madified E coli and yeast pre-tRNAs were synthesized. If this modification included the phosphodiester at the RNase P cleavage site, two different effects were observed. With some pre-tRNAs the RNase P cleavage efficiency was
Autor:
Niels H. Andersen, Alicia D. Kahle, D. Vander Velde, J S Wells, P. Principe, Mark S. Bolgar, Carol Ann Aklonis, P. V. Devasthale, L. A. Mitscher, Helen A. Ax, Donald R. Kirsch, Adrienne A. Tymiak, J.‐Y. Zou, Joseph O'sullivan, William H. Trejo, Michael A. Porubcan, Hanumaiah Telikepalli
Publikováno v:
ChemInform. 24
Publikováno v:
The Journal of Antibiotics. 45:313-319
Two novel antifungal agents, lanomycin and glucolanomycin, as well as a biologically inactive degradation product, lanomycinol, were isolated from liquid fermentations of Pycnidiophora dispersa. All three compounds share an E,E,E-triene appended to a
Autor:
Pacifico A. Principe, Alicia D. Kahle, Joseph O'sullivan, Mark S. Bolgar, Donald R. Kirsch, Carol Ann Aklonis, Michael A. Porubcan, Adrienne A. Tymiak, William H. Trejo
Publikováno v:
The Journal of Organic Chemistry. 58:535-537
The dactylocycline antibiotics are a series of tetracycline glycosides with absolute stereochemistry at C-6 (R) unprecedented amongst natural tetracyclines which, in addition, display an unusual antibiotic spectrum
Autor:
T J, Chando, D W, Everett, A D, Kahle, A M, Starrett, N, Vachharajani, W C, Shyu, K J, Kripalani, R H, Barbhaiya
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(5)
The metabolism of irbesartan, a highly selective and potent nonpeptide angiotensin II receptor antagonist, has been investigated in humans. An aliquot of pooled urine from healthy subjects given a 50-mg oral dose of [14C]irbesartan was added as a tra
Autor:
Helen A. Ax, Niels H. Andersen, Adrienne A. Tymiak, Alicia D. Kahle, Mark S. Bolgar, Michael A. Porubcan
Publikováno v:
The Journal of antibiotics. 45(12)
Fermentation of Dactylosporangium sp. (ATCC 53693) produces a mixture of tetracycline derivatives from which several related tetracycline glycosides, the dactylocyclines, were isolated and their structures determined. The most abundant glycoside in i
Publikováno v:
Journal of Heterocyclic Chemistry. 18:623-626
Analysis of the product from the Mannich reaction of 2-(2-benzofuranyl)-1H-indole via 1H and 13C nmr spectroscopy was performed. The studies included use of Pr(Fod)3 shift reagent, proton-coupled 13C spectra, deuterium isotope induced shifts and prot
Publikováno v:
Journal of Heterocyclic Chemistry. 16:1389-1392
The substituent chemical shifts of a series of para substituted-3-phenyl-as-triazine 4-oxides were studied using the Swain-Lupton F and R values. This data was compared to that obtained for parasubstituted biphenyls, phenyl pyrroles and phenyl furans