Zobrazeno 1 - 10
of 2 308
pro vyhledávání: '"A. Counihan"'
Autor:
Margaret Ebob Besem E.O, Elisabeth G. Chestnutt, Laura Donovan, Ann-Sophie Stratil, Helen Counihan, Claude Ngwayu Nkfusai, Helen Hawkings, Blanka Homolova, Kolawole Maxwell, Kevin Baker, Yakouba Zoungrana, Elvis Asangbeng Tanue, Glennise Ayuk, Noukeme Bibiche Modjenpa, Alain Metuge, Isabelle Nganmou, Dorothy Achu, Samuel Wanji, Elizabeth Berryman, Lundi-Anne Omam
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Cameroon is one of the countries with the highest burden of malaria. Since 2018, there has been an ongoing conflict in the country, which has reduced access to healthcare for populations in affected regions, and little is known ab
Externí odkaz:
https://doaj.org/article/9de56911fac8467499affd72beaeeb74
Autor:
Elvis Asangbeng Tanue, Lundi-Anne Omam, Glennis T. Ayuk, Bibiche Modjenpa Noukeme, Alain Metuge, Isabelle Nganmou, Margaret Besem Ebob, Laura Donovan, Ann-Sophie Stratil, Helen Counihan, Claude Ngwayu Nkfusai, Helen Hawkings, Blanka Homolova, Elizabeth Berryman, Maxwell Kolawole, Yakouba Zoungrana, Dorothy Achu, Samuel Wanji, Esther Njomo Omam
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Malaria remains a major global health problem often worsened by political instability and armed conflict. The purpose of the study was to explore community knowledge, attitudes and practices on malaria prevention, and to understan
Externí odkaz:
https://doaj.org/article/d910056ac14444bdbb2780e1dcb8c204
Autor:
Carlo Giannangelo, Matthew P Challis, Ghizal Siddiqui, Rebecca Edgar, Tess R Malcolm, Chaille T Webb, Nyssa Drinkwater, Natalie Vinh, Christopher Macraild, Natalie Counihan, Sandra Duffy, Sergio Wittlin, Shane M Devine, Vicky M Avery, Tania De Koning-Ward, Peter Scammells, Sheena McGowan, Darren J Creek
Publikováno v:
eLife, Vol 13 (2024)
New antimalarial drug candidates that act via novel mechanisms are urgently needed to combat malaria drug resistance. Here, we describe the multi-omic chemical validation of Plasmodium M1 alanyl metalloaminopeptidase as an attractive drug target usin
Externí odkaz:
https://doaj.org/article/332f337244e8411285174e5b2343498f
Autor:
Rebecca C. S. Edgar, Tess R. Malcolm, Ghizal Siddiqui, Carlo Giannangelo, Natalie A. Counihan, Matthew Challis, Sandra Duffy, Mrittika Chowdhury, Jutta Marfurt, Madeline Dans, Grennady Wirjanata, Rintis Noviyanti, Kajal Daware, Chathura D. Suraweera, Ric N. Price, Sergio Wittlin, Vicky M. Avery, Nyssa Drinkwater, Susan A. Charman, Darren J. Creek, Tania F. de Koning-Ward, Peter J. Scammells, Sheena McGowan
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT To combat the global burden of malaria, development of new drugs to replace or complement current therapies is urgently required. Here, we show that the compound MMV1557817 is a selective, nanomolar inhibitor of both Plasmodium falciparum an
Externí odkaz:
https://doaj.org/article/2d940180a1bd41efa98e153bebf7c041
Autor:
Sky Harper, Katrina L. Counihan, Siddhartha Kanrar, George C. Paoli, Shannon Tilman, Andrew G. Gehring
Publikováno v:
Foods, Vol 13, Iss 20, p 3304 (2024)
Six hundred million cases of disease and roughly 420,000 deaths occur globally each year due to foodborne pathogens. Current methods to screen and identify pathogens in swine, poultry, and cattle products include immuno-based techniques (e.g., immuno
Externí odkaz:
https://doaj.org/article/d8696665e348422d962c6b3c9b9cad98
Autor:
Trickey, Mitchell L.1,2 (AUTHOR) mtrickey@deakin.edu.au, Counihan, Natalie A.1,2 (AUTHOR) n.counihan@deakin.edu.au, Modak, Joyanta K.1,2 (AUTHOR) joyanta.modak@deakin.edu.au, de Koning-Ward, Tania F.1,2 (AUTHOR) taniad@deakin.edu.au
Publikováno v:
Biomolecules (2218-273X). Jul2024, Vol. 14 Issue 7, p781. 14p.
Autor:
Counihan, Timothy D.1 tcounihan@usgs.gov, Thom, Theresa2
Publikováno v:
Management of Biological Invasions. Jun2024, Vol. 15 Issue 2, p187-200. 14p.
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 781 (2024)
Parasite-derived new permeation pathways (NPPs) expressed at the red blood cell (RBC) membrane enable Plasmodium parasites to take up nutrients from the plasma to facilitate their survival. Thus, NPPs represent a potential novel therapeutic target fo
Externí odkaz:
https://doaj.org/article/c598ceda8aaa4ad2be72351fc0c4b057
Publikováno v:
BJPsych Open, Vol 10 (2024)
Background The ‘at-risk mental state’ (ARMS) for psychosis has been critiqued for its limited prognostic ability and identification of a limited proportion of those who will develop a first episode of psychosis (FEP). Broadening the search for hi
Externí odkaz:
https://doaj.org/article/c1034f7fd922474f817e190a5f9143b1
Autor:
Ethan L. Pitman, Natalie A. Counihan, Joyanta K. Modak, Mrittika Chowdury, Paul R. Gilson, Chaille T. Webb, Tania F. de Koning-Ward
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
Apicomplexan parasites that reside within a parasitophorous vacuole harbor a conserved pore-forming protein that enables small-molecule transfer across the parasitophorous vacuole membrane (PVM). In Plasmodium parasites that cause malaria, this nutri
Externí odkaz:
https://doaj.org/article/2c2296a400ba4f69a1d25067b58f9743