No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease

Autor: T. Desta, C. Strout, T. Otrok, Ciaran P. Kelly, A. Vento, P. Varunok, Richard N. Fedorak, Annette Marcantonio, Ronald Fogel, M. Reichelderfer, Michael Torbenson, Anthony J. DiMarino, A. Knoll, Peter H.R. Green, M. Wood, Premysl Bercik, Knut Ea Lundin, R. Kotfila, B. Chipps, S. Saini, T. Ritter, Sveta Shah, R. Phillips, B. Bressler, Saqib Hussain Ansari, J. Condemi, M. DeMeo, Vishal S. Chandan, B. Freilich, G. Pyle, S. Freeman, K. Gill, A. Coates, David S Sanders, Daniel C. Adelman, K. Jagarlamundi, V. Cheekati, R. Hardi, T. Welton, Vandana Nehra, R. Wohlman, K. Marks, A. Goldsobel, Joseph A. Murray, C. Corder, J. Kirstein, M. DuPree, C. Behrend, Marjorie F. Goldstein, K. Merkes, V. Narayen, M. Turner, Suzanne K. Lewis, G. Gordon, S. Liakos, S. Woods, C. Ennis, Richard Krause, R. Holmes, Carol E. Semrad, C. Devereaux, A. Basile, K. Ayub, D. Patel, M. Kaplan, J. Goldstein, D. Geenen, B. Reid, D. Suez, J. Oosthuizen, A. Collatrella, Marja-Leena Lähdeaho, M. Lamet, E. Newton, Markku Mäki, M. Kreines, Tsung Teh Wu, A. Nyberg, G. James, Valerie Byrnes, D. Stockwell, K. Yousef, Lucinda A. Harris, Jonathan Corren, A. Kravitz, C. Pepin, S. Moussa, H. Tatum, C. Curtis, K. Laskin, M. Vazquez-Roque, B. Lebwohl, S. Minton, Daniel A. Leffler, K. Friedenberg, M. Schulman

Publikováno v: Gastroenterology. 152:787-798.e2

Background & Aims Gluten ingestion leads to symptoms and small intestinal mucosal injury in patients with celiac disease. The only option is the strict lifelong exclusion of dietary gluten, which is difficult to accomplish. Many patients following a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387c03feb72edd8ea2519b493304e1ca
https://doi.org/10.1053/j.gastro.2016.11.004