Zobrazeno 1 - 10
of 1 232
pro vyhledávání: '"A. Cirella"'
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
IntroductionLike in many parts of the world, the Baltic Sea experiences a multitude of processes and stressors that influence fish stock dynamics. This paper compartmentalizes 250 publications that examine the cumulative effects and trade-offs of som
Externí odkaz:
https://doaj.org/article/3f896571037f4248b4206784789918f3
Publikováno v:
In Cities October 2024 153
Autor:
A. Pigoni, G. Delvecchio, C. Pini, L. Cirella, C. Prunas, N. Turtulici, L. Squarcina, P. Brambilla
Publikováno v:
European Psychiatry, Vol 67, Pp S348-S349 (2024)
Introduction Bipolar disorder (BD) is a recurrent disorder, causing functional impairment and raised mortality, particularly due to suicide. However, the difficulty in predicting suicidal behaviors relies in the lack of clear biomarkers. Machine lear
Externí odkaz:
https://doaj.org/article/b4b0de6bd7ba4497918fde90077e8788
Autor:
Ignacio Melero, Maria C Ochoa, Carmen Molina, Sandra Sanchez‐Gregorio, Saray Garasa, Carlos Luri‐Rey, Sandra Hervas‐Stubbs, Noelia Casares, Edurne Elizalde, Gabriel Gomis, Assunta Cirella, Pedro Berraondo, Alvaro Teijeira, Maite Alvarez
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-16 (2023)
Abstract NK‐cell reactivity against cancer is conceivably suppressed in the tumor microenvironment by the interaction of the inhibitory receptor NKG2A with the non‐classical MHC‐I molecules HLA‐E in humans or Qa‐1b in mice. We found that in
Externí odkaz:
https://doaj.org/article/dad7d8e3e32044ab82bb7ccfc15b4a39
Autor:
Assunta Cirella, Elixabet Bolaños, Carlos Luri-Rey, Claudia Augusta Di Trani, Irene Olivera, Gabriel Gomis, Javier Glez-Vaz, Beatrice Pinci, Saray Garasa, Sandra Sánchez-Gregorio, Arantza Azpilikueta, Iñaki Eguren-Santamaria, Karmele Valencia, Belén Palencia, Maite Alvarez, Maria C. Ochoa, Álvaro Teijeira, Pedro Berraondo, Ignacio Melero
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 668-682 (2023)
Intratumoral immunotherapy strategies for cancer based on interleukin-12 (IL-12)-encoding cDNA and mRNA are under clinical development in combination with anti-PD-(L)1 monoclonal antibodies. To make the most of these approaches, we have constructed c
Externí odkaz:
https://doaj.org/article/0cbeb48e82c4432eb1d5f41226df6231
Autor:
Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Maite Alvarez, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Nuria Ardaiz, Alvaro Teijeira, Elixabet Bolaños, José González-Gomariz, Itziar Otano, Fernando Aranda, Belén Palencia, Aina Segués, Shuyu Huang, Sander M.J. van Duijnhoven, Andrea van Elsas, Ignacio Melero, Pedro Berraondo
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 599-616 (2023)
IL-12 is a potent cytokine for cancer immunotherapy. However, its systemic delivery as a recombinant protein has shown unacceptable toxicity in the clinic. Currently, the intratumoral injection of IL-12-encoding mRNA or DNA to avoid such side effects
Externí odkaz:
https://doaj.org/article/b7ab44ddf91c4d09a6a701937d803612
Autor:
Alessio Russo, Giuseppe T. Cirella
Publikováno v:
Land, Vol 13, Iss 6, p 786 (2024)
The rapid advancement of urbanization, evident in the relentless expansion of concrete jungles, poses a significant threat to the delicate balance of ecosystem services [...]
Externí odkaz:
https://doaj.org/article/5ab85bdf40694e79bd6e91d2d3c656c9
Publikováno v:
In European Management Journal February 2024 42(1):46-56
Autor:
Maite Alvarez, Carmen Molina, Saray Garasa, Maria C. Ochoa, Maria E Rodriguez-Ruiz, Gabriel Gomis, Assunta Cirella, Irene Olivera, Javier Glez-Vaz, Jose Gonzalez-Gomariz, carlos luri-Rey, arantza azpilikueta, Elixabet Bolaños, Alvaro Teijeira, Pedro Berraondo, Marisol Quintero, Ignacio Melero
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTBO-112 is a poly I:C-based viral mimetic that exerts anti-tumor efficacy when intratumorally delivered in mouse models. Intratumoral BO-112 synergizes in mice with systemic anti-PD-1 mAbs and this combination has attained efficacy in PD1-refr
Externí odkaz:
https://doaj.org/article/44e860c9bad74e59994cd04f69e8b8a5
Autor:
Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Irene Olivera, Elizabeth Bolaños, José González-Gomariz, Maite Álvarez, Iñaki Etxeberria, Belen Palencia, Álvaro Teijeira, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTPrevious studies have shown that local delivery of tumor antigen-specific CD8+ T lymphocytes engineered to transiently express single-chain IL-12 mRNA is highly efficacious. Peritoneal dissemination of cancer is a frequent and often fatal pat
Externí odkaz:
https://doaj.org/article/7995ddacfe9f449ca1ff8dccf0f9a256