Zobrazeno 1 - 10
of 338
pro vyhledávání: '"A. Castelvetri"'
Autor:
Peter Androvic, Martina Schifferer, Katrin Perez Anderson, Ludovico Cantuti-Castelvetri, Hanyi Jiang, Hao Ji, Lu Liu, Garyfallia Gouna, Stefan A. Berghoff, Simon Besson-Girard, Johanna Knoferle, Mikael Simons, Ozgun Gokce
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Understanding the complexity of cellular function within a tissue necessitates the combination of multiple phenotypic readouts. Here, we developed a method that links spatially-resolved gene expression of single cells with their ultrastructu
Externí odkaz:
https://doaj.org/article/c66140bd92484a63acc14ed3e67b9854
Publikováno v:
In Seminars in Immunology January 2022 59
Akademický článek
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Autor:
Safaiyan, Shima, Besson-Girard, Simon, Kaya, Tuğberk, Cantuti-Castelvetri, Ludovico, Liu, Lu, Ji, Hao, Schifferer, Martina, Gouna, Garyfallia, Usifo, Fumere, Kannaiyan, Nirmal, Fitzner, Dirk, Xiang, Xianyuan, Rossner, Moritz J., Brendel, Matthias, Gokce, Ozgun, Simons, Mikael
Publikováno v:
In Neuron 7 April 2021 109(7):1100-1117
Autor:
Alessio Colombo, Lina Dinkel, Stephan A. Müller, Laura Sebastian Monasor, Martina Schifferer, Ludovico Cantuti-Castelvetri, Jasmin König, Lea Vidatic, Tatiana Bremova-Ertl, Andrew P. Lieberman, Silva Hecimovic, Mikael Simons, Stefan F. Lichtenthaler, Michael Strupp, Susanne A. Schneider, Sabina Tahirovic
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Niemann-Pick type C disease is a rare childhood neurodegenerative disorder predominantly caused by mutations in NPC1, resulting in abnormal late endosomal and lysosomal defects. Here the authors show that NPC1 disruption largely impairs microglial fu
Externí odkaz:
https://doaj.org/article/086477f8dbac4c818ed45236ab495029
Autor:
Kai Schlepckow, Kathryn M Monroe, Gernot Kleinberger, Ludovico Cantuti‐Castelvetri, Samira Parhizkar, Dan Xia, Michael Willem, Georg Werner, Nadine Pettkus, Bettina Brunner, Alice Sülzen, Brigitte Nuscher, Heike Hampel, Xianyuan Xiang, Regina Feederle, Sabina Tahirovic, Joshua I Park, Rachel Prorok, Cathal Mahon, Chun‐Chi Liang, Ju Shi, Do Jin Kim, Hanna Sabelström, Fen Huang, Gilbert Di Paolo, Mikael Simons, Joseph W Lewcock, Christian Haass
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 4, Pp 1-22 (2020)
Abstract Triggering receptor expressed on myeloid cells 2 (TREM2) is essential for the transition of homeostatic microglia to a disease‐associated microglial state. To enhance TREM2 activity, we sought to selectively increase the full‐length prot
Externí odkaz:
https://doaj.org/article/a1d63c8ac22b4f22bf081e18a44b1145
Autor:
Cantuti-Castelvetri, Ludovico, Fitzner, Dirk, Bosch-Queralt, Mar, Weil, Marie-Theres, Su, Minhui, Sen, Paromita, Ruhwedel, Torben, Mitkovski, Miso, Trendelenburg, George, Lütjohann, Dieter, Möbius, Wiebke, Simons, Mikael
Publikováno v:
Science, 2018 Feb 01. 359(6376), 684-688.
Externí odkaz:
https://www.jstor.org/stable/26401452
Akademický článek
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Autor:
Tuğberk Kaya, Nicola Mattugini, Lu Liu, Hao Ji, Ludovico Cantuti-Castelvetri, Jianping Wu, Martina Schifferer, Janos Groh, Rudolf Martini, Simon Besson-Girard, Seiji Kaji, Arthur Liesz, Ozgun Gokce, Mikael Simons
Publikováno v:
Nature neuroscience 25(11), 1446-1457 (2022). doi:10.1038/s41593-022-01183-6
A hallmark of nervous system aging is a decline of white matter volume and function, but the underlying mechanisms leading to white matter pathology are unknown. In the present study, we found age-related alterations of oligodendrocyte cell state wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633eb56ce91b5ce4422df1cae8b81df0
https://doi.org/10.1038/s41593-022-01183-6
https://doi.org/10.1038/s41593-022-01183-6
Publikováno v:
In BBA - Molecular and Cell Biology of Lipids August 2015 1851(8):999-1005