Zobrazeno 1 - 9
of 9
pro vyhledávání: '"A. Carolin Seefeldt"'
Autor:
Javier, Aguirre Rivera, Jimmy, Larsson, Ivan L, Volkov, A Carolin, Seefeldt, Suparna, Sanyal, Magnus, Johansson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance To address the public health challenges caused by the spread of antibiotic resistance, it is critical to enhance our understanding of the mechanisms of action of these compounds. In the present study, we use superresolved single-molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2b952d719e4d6bd1775738a473c1d25
https://pubmed.ncbi.nlm.nih.gov/33619089
https://pubmed.ncbi.nlm.nih.gov/33619089
Autor:
Alba Herrero del Valle, C. Axel Innis, Britta Seip, Guénaël Sacheau, Iñaki Cervera-Marzal, A. Carolin Seefeldt
Publikováno v:
Nature Microbiology
Nature microbiology
Nature microbiology
Polyamines are essential metabolites that play an important role in cell growth, stress adaptation, and microbial virulence1–3. In order to survive and multiply within a human host, pathogenic bacteria adjust the expression and activity of polyamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2af4442df42bb708b5a29a6a770a2dd
Autor:
Britta Seip, A. Carolin Seefeldt, Alba Herrero del Valle, Iñaki Cervera-Marzal, C. Axel Innis, Guénaël Sacheau
Publikováno v:
Nature Microbiology. 5:653-654
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2efaadb854a9b27f85b25119047fc80
https://doi.org/10.1038/s41564-020-0708-y
https://doi.org/10.1038/s41564-020-0708-y
Direct Measurements of Erythromycin’s Effect on Protein Synthesis Kinetics in Living Bacterial Cells
Publikováno v:
Journal of Molecular Biology. 433:166942
Macrolide antibiotics, such as erythromycin, bind to the nascent peptide exit tunnel (NPET) of the bacterial ribosome and modulate protein synthesis depending on the nascent peptide sequence. Whereas in vitro biochemical and structural methods have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede85683ab776de691879bbd97cdb452
https://doi.org/10.1016/j.jmb.2021.166942
https://doi.org/10.1016/j.jmb.2021.166942
Autor:
Britta Seip, A. Carolin Seefeldt
Publikováno v:
BIOspektrum. 23:516-518
In all living cells ribosomes are responsible for the translation of genetic information into the corresponding protein sequence. This central position does not only make them a valuable target for antibiotics but also offers great possibilities to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0bfd768d29165b3bbf3887578ff4909
https://doi.org/10.1007/s12268-017-0833-1
https://doi.org/10.1007/s12268-017-0833-1
Publikováno v:
Methods (San Diego, Calif.).
Chloramphenicol is a broad-spectrum antibiotic targeting the protein synthesis machinery by binding to the bacterial ribosome. Chloramphenicol has been considered a classic general inhibitor of translation, blocking the accommodation of aa-tRNA into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d43a37e812e6fccedd3c6425747ed1a
https://pubmed.ncbi.nlm.nih.gov/30742999
https://pubmed.ncbi.nlm.nih.gov/30742999
Autor:
Gilles Guichard, A. Carolin Seefeldt, Mario Mardirossian, Daniel N. Wilson, Fabian Nguyen, Michael Graf, Marco Scocchi, C. Axel Innis
Covering: up to 2017 The innate immune system employs a broad array of antimicrobial peptides (AMPs) to attack invading microorganisms. While most AMPs act by permeabilizing the bacterial membrane, specific subclasses of AMPs have been identified tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22681a2ab7d7dddf4344f53a2df74f60
http://pubs.rsc.org/en/Content/ArticleLanding/2017/NP/C7NP00020K
http://pubs.rsc.org/en/Content/ArticleLanding/2017/NP/C7NP00020K
Autor:
Natacha Pérébaskine, Marco Scocchi, Michael Graf, A. Carolin Seefeldt, Daniel N. Wilson, C. Axel Innis, Stefan Arenz, Fabian Nguyen, Mario Mardirossian
Publikováno v:
Nucleic Acids Research
Proline-rich antimicrobial peptides (PrAMPs) produced as part of the innate immune response of animals, insects and plants represent a vast, untapped resource for the treatment of multidrug-resistant bacterial infections. PrAMPs such as oncocin or ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fb423677cdc296e83ad5a5cf3836c1
https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkv1545
https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkv1545
Autor:
A. Carolin Seefeldt, Stéphanie Antunes, Natacha Pérébaskine, Daniel N. Wilson, Céline Douat, Gilles Guichard, Michael Graf, C. Axel Innis, Krishna Kishore Inampudi, Stefan Arenz, Fabian Nguyen
Publikováno v:
Nature structuralmolecular biology. 22(6)
The increasing prevalence of multidrug-resistant pathogenic bacteria is making current antibiotics obsolete. Proline-rich antimicrobial peptides (PrAMPs) display potent activity against Gram-negative bacteria and thus represent an avenue for antibiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667d03ff779712b4426af85581d6ffaa
https://pubmed.ncbi.nlm.nih.gov/25984971
https://pubmed.ncbi.nlm.nih.gov/25984971