Výsledky vyhledávání - "A. Cagnolini"

Akademický článek

P-072 - Mild and direct 18F radiofluorination of tetrazines through sulfonium salt precursors

Autor: Zhang, Wei, Xiong, Hui, Huang, Xuan, Cagnolini, Aldo, Hoye, Adam, Lim, Nathaniel Anthony, Horchler, Carey

Publikováno v: In Nuclear Medicine and Biology May-June 2022 108-109 Supplement:S88-S89

68Ga-AMBA and 18F-FDG for preclinical PET imaging of breast cancer: effect of tamoxifen treatment on tracer uptake by tumor

Autor: Aurélie Prignon, Claire Provost, Jean-Noël Talbot, Françoise Montravers, Adrian D. Nunn, Laura E. Lantry, Aldo Cagnolini, Anne Gruaz-Guyon, Valérie Nataf

Publikováno v: Nuclear Medicine and Biology. 42:92-98

Introduction AMBA is a bombesin analogue that binds to GRPr. In a mouse model of estrogen-dependent human breast cancer, we tested whether 68 Ga-AMBA can be used for PET detection of GRPr-expressing tumors and could be more accurate than 18 F-FDG to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87156c30c9ab5c0e71ea58945c44c37
https://doi.org/10.1016/j.nucmedbio.2014.10.003

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Tetradentate bis-phosphine ligands (P2N2 and P2S2) and their Rh(III), Ni(II) and 105Rh Complexes: X-ray crystal structures of trans-[RhCl2(L2)]PF6, [Ni(L2)](PF6)2 and μ-O2SO2-[Ni(L5)]2(PF6)2

Autor: Beau Ballard, Tammy L. Rold, Hendrick P. Engelbrecht, Kattesh V. Katti, Aldo Cagnolini, Raghuraman Kannan, Cathy S. Cutler, Charles L. Barnes, Timothy J. Hoffman, Silvia S. Jurisson

Publikováno v: Nuclear Medicine and Biology. 38:63-76

Introduction Tetradentate acyclic and macrocyclic diphosphine ligands (P 2 N 2 and P 2 S 2 ) have been synthesized and characterized as potential chelates for Rh(III). Methods The coordination complexes [RhCl 2 ( L1 )]Cl, trans -[RhCl 2 ( L2 )]PF 6 ,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a683a3aee5f8d91b5dbcdb84cfdeae9
https://doi.org/10.1016/j.nucmedbio.2010.06.013

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177Lu-AMBA Biodistribution, Radiotherapeutic Efficacy, Imaging, and Autoradiography in Prostate Cancer Models with Low GRP-R Expression

Autor: Laura E. Lantry, Michael F. Tweedle, Adrian D. Nunn, Karen E. Linder, Aldo Cagnolini, Jianqing Chen, Jaclyn Fox, Weiwei Feng, Mary Ellen Maddalena

Publikováno v: Journal of Nuclear Medicine. 50:2017-2024

(177)Lu-DO3A-CH(2)CO-G-4-aminobenzoyl-Q-W-A-V-G-H-L-M-NH(2) ((177)Lu-AMBA) is a radiolabeled bombesin derivative that is bound and internalized by cells expressing the G-protein-coupled gastrin-releasing peptide receptor (GRP-R) and is currently in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c42dac34a4ce5a911124add39ec132
https://doi.org/10.2967/jnumed.109.064444

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In Vitro and in Vivo Metabolism of Lu-AMBA, a GRP-Receptor Binding Compound, and the Synthesis and Characterization of Its Metabolites

Autor: Natarajan Raju, Edmund Metcalfe, Jianqing Chen, Laura E. Lantry, Aldo Cagnolini, Weiwei Feng, Hong Fan, Karen E. Linder, Stephen M. Eaton, Rolf E. Swenson, Adrian D. Nunn, Thangavel Arunachalam

Publikováno v: Bioconjugate Chemistry. 20:1171-1178

The metabolism of (177)Lu-AMBA (AMBA = DO3A-CH(2)CO-G-(4-aminobenzoyl)-QWAVGHLM-NH(2)), a radiotherapeutic compound in clinical development that binds to GRP and NMB receptors, was studied in vitro (mouse, rat and human plasma, mouse kidney homogenat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9726448053270fb44cadc532cb9d21
https://doi.org/10.1021/bc9000189

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