Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells

Autor: Eric Eldering, Lisette Waanders, Lieve E H van der Donk, Louis S Ates, Janneke Maaskant, John L van Hamme, Jaco A C van Bruggen, Joanne M Rietveld, Wilbert Bitter, Teunis B H Geijtenbeek, Coenraad P Kuijl

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)

Background Interferon (IFN)-β induction via activation of the stimulator of interferon genes (STING) pathway has shown promising results in tumor models. STING is activated by cyclic dinucleotides such as cyclic GMP–AMP dinucleotides with phosphod

Externí odkaz: https://doaj.org/article/31940c490bd64fc09c995d4d78516705

Healthy Ageing and Intellectual Disability study: summary of findings and the protocol for the 10-year follow-up study

Autor: Patrick J E Bindels, Roy G Elbers, Marleen J de Leeuw, Alyt Oppewal, Mireille W E J Knulst, Marco C van Maurik, Marjoleine C van Bruggen, Thessa I M Hilgenkamp, Dederieke A M Maes-Festen

Publikováno v: BMJ Open, Vol 12, Iss 2 (2022)

Externí odkaz: https://doaj.org/article/4d3d4d3d9e584230ba85222a3f28a168

The black-necked grebe Podiceps nigricollis. A new bird record for the Kruger National Park

Autor: A. C. van Bruggen

Publikováno v: Koedoe: African Protected Area Conservation and Science, Vol 19, Iss 1, Pp 169-170 (1976)

The avifauna of the Kruger National Park (KNP) was described in detail by Kemp (1974). However, species new to the list are bound to turn up occasionally. Joubert and English (1973), who discovered the occurrence of the crimson-breasted shrike Laniar

Externí odkaz: https://doaj.org/article/02a5e8e12dd44797be72bfa42a65a6f5

Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells

Autor: Lisette Waanders, Lieve E H van der Donk, Louis S Ates, Janneke Maaskant, John L van Hamme, Eric Eldering, Jaco A C van Bruggen, Joanne M Rietveld, Wilbert Bitter, Teunis B H Geijtenbeek, Coenraad P Kuijl

Publikováno v: Journal for immunotherapy of cancer, 11(4). BioMed Central Ltd.
Waanders, L, van der Donk, L E H, Ates, L S, Maaskant, J, van Hamme, J L, Eldering, E, van Bruggen, J A C, Rietveld, J M, Bitter, W, Geijtenbeek, T B H & Kuijl, C P 2023, ' Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells ', Journal for Immunotherapy of Cancer, vol. 11, no. 4, jitc-2022-005839, pp. 1-13 . https://doi.org/10.1136/jitc-2022-005839
Journal for Immunotherapy of Cancer, 11(4):jitc-2022-005839. BioMed Central
Waanders, L, van der Donk, L E H, Ates, L S, Maaskant, J, van Hamme, J L, Eldering, E, van Bruggen, J A C, Rietveld, J M, Bitter, W, Geijtenbeek, T B H & Kuijl, C P 2023, ' Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells ', Journal for Immunotherapy of Cancer, vol. 11, no. 4, jitc-2022-005839 . https://doi.org/10.1136/jitc-2022-005839
Journal for Immunotherapy of Cancer, 11(4):jitc-2022-005839, 1-13. BioMed Central

BackgroundInterferon (IFN)-β induction via activation of the stimulator of interferon genes (STING) pathway has shown promising results in tumor models. STING is activated by cyclic dinucleotides such as cyclic GMP–AMP dinucleotides with phosphodi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2149b7bf3d883993fac5482fcf45611a
https://pure.amc.nl/en/publications/ectopic-expression-of-cgas-in-salmonella-typhimurium-enhances-stingmediated-ifn-response-in-human-macrophages-and-dendritic-cells(946d907b-8e7c-4291-b92d-ff52383ad71b).html

Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells

Autor: J. A. C. van Bruggen, G. J. W. van der Windt, M. Hoogendoorn, J. Dubois, Arnon P. Kater, F. S. Peters

Publikováno v: Blood advances, 6(14):14, 4185-4195. American Society of Hematology
Blood, 6(14), 4185-4195. American Society of Hematology
van Bruggen, J A C, van der Windt, G J W, Hoogendoorn, M, Dubois, J, Kater, A P & Peters, F S 2022, ' Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells ', Blood, vol. 6, no. 14, pp. 4185-4195 . https://doi.org/10.1182/bloodadvances.2022007034
Blood advances. American Society of Hematology

Acquired T-cell dysfunction is characteristic of chronic lymphocytic leukemia (CLL) and is associated with reduced efficacy of T cell–based therapies. A recently described feature of dysfunctional CLL-derived CD8 T cells is reduced metabolic plasti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915cce59982bfb2da80f8394cb2cf11d
https://pure.amc.nl/en/publications/depletion-of-cll-cells-by-venetoclax-treatment-reverses-oxidative-stress-and-impaired-glycolysis-in-cd4-t-cells(00276d61-cea4-4d1c-92c1-c5034bbb7044).html