Výsledky vyhledávání - "A. C. Specian"

Akademický článek

'You can’t put your head down like an ostrich' - Emotional experiences associated to clozapine treatment protocol reported by patients with schizophrenia seen in a Brazilian university specialized service: a clinical-qualitative study

Autor: E. R. Turato, J.-B. A. Santos, P. Dalgalarrondo, C. R. Dantas, F.-C. Specian-Jr, L. S. Valladão

Publikováno v: European Psychiatry, Vol 66, Pp S260-S260 (2023)

Introduction Understanding the psychological meanings of a rigorous protocol for introducing a drug to patients is a challenge of emotional management for clinical professionals. Clozapine is an effective drug for patients with schizophrenia resistan

Externí odkaz: https://doaj.org/article/138f8354975e40ca8487a5331e7cde0c

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Synthesis of (2R,4'R,8'R)-.alpha.-tocopheryl acetate (vitamin E acetate) using [3,3] sigmatropic rearrangement

Autor: Ka-Kong Chan, Anthony C. Specian, Gabriel Saucy

Publikováno v: The Journal of Organic Chemistry. 43:3435-3440

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cee495f7fda5a9a4f6aadd6cc51375e7
https://doi.org/10.1021/jo00412a001

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Fluorinated retinoic acids and their analogs. 2. Synthesis and biological activity of aromatic 4-fluoro analogs

Autor: K K, Chan, A C, Specian, B A, Pawson

Publikováno v: Journal of Medicinal Chemistry. 24:101-104

Ethyl (E,Z,E,E)-3,7-dimethyl-4-fluoro-9-(4-methoxy-2,3,6-trimethylphenyl)nonatetraenoate (10a) has been found to cause a marked regression of chemically induced skin papillomas in mice. A new synthesis of this compound was achieved by condensation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0433a2916aa651988a941d64ce662b
https://doi.org/10.1021/jm00133a020

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Fluorinated retinoic acids and their analogues. 1. Synthesis and Biological activity of (4-methoxy-2,3,6-trimethylphenyl)nonatetraenoic acid analogues

Autor: B A, Pawson, K K, Chan, J, DeNoble, R J, Han, V, Piermattie, A C, Specian, S, Srisethnil, P W, Trown, O, Bohoslawec, L J, Machlin, E, Gabriel

Publikováno v: Journal of medicinal chemistry. 22(9)

(4-Methoyx-2,3,6-trimethylphenyl)nonatetraenoic acids, esters, and amides (analogues of retinoic acid) bearing a fluorine atom(s) or a trifluoromethyl group on the polyene side chain were synthesized. The biological activities of these compounds and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76789df98b98899a5269fa119ca93aa
https://pubmed.ncbi.nlm.nih.gov/490550

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Synthetic studies on (2R,4'R,8'R)-alpha-tocopherol. Facile syntheses of optically active, saturated, acyclic isoprenoids via stereospecific [3,3]sigmatropic rearrangements

Autor: Noal Cohen, Ka-Kong Chan, Anthony C. Specian, James P. De Noble, Gabriel Saucy

Publikováno v: The Journal of organic chemistry. 41(22)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1784f92a5656b38028db741422f048be
https://pubmed.ncbi.nlm.nih.gov/978300

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ChemInform Abstract: FLUORINATED RETINOIC ACIDS AND THEIR ANALOGS. 1. SYNTHESIS AND BIOLOGICAL ACTIVITY OF (4-METHOXY-2,3,6-TRIMETHYLPHENYL)NONATETRAENOIC ACID ANALOGS

Autor: P. W. Trown, S. Srisethnil, A. C. Specian, E. Gabriel, V. Piermattie, O. Bohoslawec, L. J. Machlin, Ka-Kong Chan, R. J. L. Han, B. A. Pawson, J. Denoble

Publikováno v: Chemischer Informationsdienst. 11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::178bd5639abd7896d9bf8d274babc984
https://doi.org/10.1002/chin.198005201

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