Zobrazeno 1 - 10
of 687
pro vyhledávání: '"A. C. Shore"'
Autor:
F. Casanova, D. D. Adingupu, F. Adams, K. M. Gooding, H. C. Looker, K. Aizawa, F. Dove, S. Elyas, J. J. F. Belch, P. E. Gates, R. C. Littleford, M. Gilchrist, H. M. Colhoun, A. C. Shore, F. Khan, W. D. Strain
Publikováno v:
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-11 (2017)
Abstract Background Good glycaemic control in type 2 diabetes (T2DM) protects the microcirculation. Current guidelines suggest glycaemic targets be relaxed in advanced diabetes. We explored whether disease duration or pre-existing macrovascular compl
Externí odkaz:
https://doaj.org/article/fa3ba5c4c84d4c1aa8248f75dd5ba348
Autor:
Kunihiko Aizawa, Alun D. Hughes, Francesco Casanova, Kim M. Gooding, Phillip E. Gates, David M. Mawson, Jennifer Williams, Isabel Goncalves, Jan Nilsson, Faisel Khan, Helen M. Colhoun, Carlo Palombo, Kim H. Parker, Angela C. Shore
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 3290-3298 (2024)
Abstract Aims Parameters derived from reservoir‐excess pressure analysis have been demonstrated to predict cardiovascular events. Thus, altered reservoir‐excess pressure parameters could have a detrimental effect on highly‐perfused organs like
Externí odkaz:
https://doaj.org/article/90221f9627714e60b5164d980c6f572e
Autor:
Emily Chesshyre, Fiona C. Warren, Angela C. Shore, Jane C. Davies, Darius Armstrong-James, Adilia Warris
Publikováno v:
Journal of Fungi, Vol 10, Iss 9, p 599 (2024)
Observational studies indicate that Aspergillus colonization and allergic bronchopulmonary aspergillosis (ABPA) in people with cystic fibrosis (CF) are associated with poorer lung health and increased disease severity. We performed a longitudinal obs
Externí odkaz:
https://doaj.org/article/7a3851802f7d45e689e90d09fda8e59d
Autor:
Andrew N. Jordan, Christine Anning, Lindsay Wilkes, Claire Ball, Nicola Pamphilon, Christopher E. Clark, Nicholas G. Bellenger, Angela C. Shore, Andrew S. P. Sharp, Jose M. Valderas
Publikováno v:
Health and Quality of Life Outcomes, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Hypertension is a highly prevalent condition, with optimal treatment to BP targets conferring significant gains in terms of cardiovascular outcomes. Understanding why some patients do not achieve BP targets would be enhanced throu
Externí odkaz:
https://doaj.org/article/1a66dbfedbc04164b112da27c56ed56f
Autor:
Chuanyan Wu, Yan Borné, Rui Gao, Maykel López Rodriguez, William C. Roell, Jonathan M. Wilson, Ajit Regmi, Cheng Luan, Dina Mansour Aly, Andreas Peter, Jürgen Machann, Harald Staiger, Andreas Fritsche, Andreas L. Birkenfeld, Rongya Tao, Robert Wagner, Mickaël Canouil, Mun-Gwan Hong, Jochen M. Schwenk, Emma Ahlqvist, Minna U. Kaikkonen, Peter Nilsson, Angela C. Shore, Faisel Khan, Andrea Natali, Olle Melander, Marju Orho-Melander, Jan Nilsson, Hans-Ulrich Häring, Erik Renström, Claes B. Wollheim, Gunnar Engström, Jianping Weng, Ewan R. Pearson, Paul W. Franks, Morris F. White, Kevin L. Duffin, Allan Arthur Vaag, Markku Laakso, Norbert Stefan, Leif Groop, Yang De Marinis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Follistatin promotes in type 2 diabetes (T2D) pathogenesis in model animals and is elevated in patients with T2D. Here the authors report that plasma follistatin associates with increased risk of incident T2D in two longitudinal cohorts, and show tha
Externí odkaz:
https://doaj.org/article/718976e80f5648f99659b5ea904f47e5
Autor:
Andrew N. Jordan, Jon Fulford, Kim Gooding, Christine Anning, Lindsay Wilkes, Claire Ball, Nicola Pamphilon, David Mawson, Christopher E. Clark, Angela C. Shore, Andrew S. P. Sharp, Nicholas G. Bellenger
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 23, Iss 1, Pp 1-11 (2021)
Abstract Background Left ventricular (LV) hypertrophy (LVH) in uncontrolled hypertension is an independent predictor of mortality, though its regression with treatment improves outcomes. Retrospective data suggest that early control of hypertension p
Externí odkaz:
https://doaj.org/article/688c5272a3004040832af28a006555d8
Autor:
Annelie Shami, Andreas Edsfeldt, Eva Bengtsson, Jan Nilsson, Angela C. Shore, Andrea Natali, Faisel Khan, Esther Lutgens, Isabel Gonçalves
Publikováno v:
Journal of Stroke, Vol 23, Iss 3, Pp 367-376 (2021)
Background and Purpose CD40 and CD40 ligand (CD40L) are costimulatory molecules of the tumor necrosis factor receptor superfamily and well known for their involvement in inflammatory diseases: atherosclerotic mouse models with disrupted CD40 signalli
Externí odkaz:
https://doaj.org/article/a59fad5770eb4319b4cb7cdafcbcb201
Autor:
Josie Carmichael, Hassan Fadavi, Fukashi Ishibashi, Susan Howard, Andrew J. M. Boulton, Angela C. Shore, Mitra Tavakoli
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveScreening for diabetic peripheral neuropathy (DPN) is essential for early detection and timely intervention. Quantitative assessment of small nerve fiber damage is key to the early diagnosis and assessment of its progression. Corneal confoca
Externí odkaz:
https://doaj.org/article/30fe9f975c1440479683d5afd2b9ffab
Autor:
Kim M. Gooding, Chrysta Lienczewski, Massimo Papale, Niina Koivuviita, Marlena Maziarz, Anna-Maria Dutius Andersson, Kanishka Sharma, Paola Pontrelli, Alberto Garcia Hernandez, Julie Bailey, Kay Tobin, Virva Saunavaara, Anna Zetterqvist, David Shelley, Irvin Teh, Claire Ball, Sapna Puppala, Mark Ibberson, Anil Karihaloo, Kaj Metsärinne, Rosamonde E. Banks, Peter S. Gilmour, Michael Mansfield, Mark Gilchrist, Dick de Zeeuw, Hiddo J. L. Heerspink, Pirjo Nuutila, Matthias Kretzler, Matthew Welberry Smith, Loreto Gesualdo, Dennis Andress, Nicolas Grenier, Angela C. Shore, Maria F. Gomez, Steven Sourbron, for the BEAt-DKD consortium
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Diabetic kidney disease (DKD) remains one of the leading causes of premature death in diabetes. DKD is classified on albuminuria and reduced kidney function (estimated glomerular filtration rate (eGFR)) but these have modest value
Externí odkaz:
https://doaj.org/article/e94cbf7fb6ec48ce9d18b5b1e307048f
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/82d408820f15497f8e02339c38398cfe