Zobrazeno 1 - 10
of 86
pro vyhledávání: '"A. C. Padilha"'
Autor:
Jacob Schimetz, Pranav Shah, Charles Keese, Chris Dehnert, Michael Detweiler, Sam Michael, Catherine Toniatti-Yanulavich, Xin Xu, Elias C. Padilha
Publikováno v:
SLAS Technology, Vol 29, Iss 1, Pp 100116- (2024)
Transepithelial electrical resistance (TEER) is a widely used technique for quantifying the permeability of epithelial and endothelial cell layers. However, traditional methods of measuring TEER are limited to single timepoint measurements and can su
Externí odkaz:
https://doaj.org/article/a609b454386141629841489eac1b65f4
Autor:
Rintaro Kato, Wenyu Zeng, Vishal B. Siramshetty, Jordan Williams, Md Kabir, Natalie Hagen, Elias C. Padilha, Amy Q. Wang, Ewy A. Mathé, Xin Xu, Pranav Shah
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Efficiently circumventing the blood-brain barrier (BBB) poses a major hurdle in the development of drugs that target the central nervous system. Although there are several methods to determine BBB permeability of small molecules, the Parallel Artific
Externí odkaz:
https://doaj.org/article/f2af9b80c1964c48b71ae481314f0507
Autor:
Geovanny Barroso, Carlos Barreto, Aline C. Padilha, Juliano B. Pazini, Jandir C. Santos, Lucas L. Godoy, Pedro T. Yamamoto
Publikováno v:
Entomological Communications, Vol 5 (2023)
In this study we used the average annual temperature in Brazil and four warming predictions to propose a maximum thermal threshold for the predatory mite Cosmolaelaps brevistilis (Karg, 1978) (Mesostigmata: Laelapidae) as an experimental model. Then,
Externí odkaz:
https://doaj.org/article/e21d7894910341d291fe91847bdda137
Autor:
Gabriella P. Belfort, Dayana R. Farias, Patricia de C. Padilha, Letícia B. G. da Silva, Karina dos Santos, Mayara S. dos Santos, Lenita Zajdenverg, Elisa Keating, Claudia Saunders
Publikováno v:
Life, Vol 13, Iss 11, p 2191 (2023)
Background: This study aimed to investigate the influence of the dietary approaches to stop hypertension (DASH) diet on gestational weight gain and perinatal outcomes in pregnant women with pre-existing diabetes mellitus (PDM). Methods: A randomized,
Externí odkaz:
https://doaj.org/article/a47d8f2475e84c31bd35c0a927d704dc
Autor:
Mengbi Yang, Amy Q. Wang, Elias C. Padilha, Pranav Shah, Natalie R. Hagen, China Ryu, Khalida Shamim, Wenwei Huang, Xin Xu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Niclosamide (Nc) is an FDA-approved anthelmintic drug that was recently identified in a drug repurposing screening to possess antiviral activity against SARS-CoV-2. However, due to the low solubility and permeability of Nc, its in vivo
Externí odkaz:
https://doaj.org/article/7f49f978d6434fb4a382907efaad474b
Autor:
Amy Q. Wang, Natalie R. Hagen, Elias C. Padilha, Mengbi Yang, Pranav Shah, Catherine Z. Chen, Wenwei Huang, Pramod Terse, Philip Sanderson, Wei Zheng, Xin Xu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Preclinical pharmacokinetics (PK) and In Vitro ADME properties of GS-441524, a potential oral agent for the treatment of Covid-19, were studied. GS-441524 was stable in vitro in liver microsomes, cytosols, and hepatocytes of mice, rats, monkeys, dogs
Externí odkaz:
https://doaj.org/article/96df82be203a4011897c62432885afde
Autor:
Md Kabir, Elias C. Padilha, Pranav Shah, Ruili Huang, Srilatha Sakamuru, Eric Gonzalez, Lin Ye, Xin Hu, Mark J. Henderson, Menghang Xia, Xin Xu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cytochrome P450 (CYP) 3A7 is one of the major xenobiotic metabolizing enzymes in human embryonic, fetal, and newborn liver. CYP3A7 expression has also been observed in a subset of the adult population, including pregnant women, as well as in various
Externí odkaz:
https://doaj.org/article/f9d354218d0943e386f9679ca6dac038
Autor:
Salazar, Diego F.U., Demattê, José A.M., Vicente, Luiz E., Guimarães, Clécia C.B., Sayão, Veridiana M., Cerri, Carlos E.P., de C. Padilha, Manuela C., Mendes, Wanderson De S.
Publikováno v:
In Geoderma 1 March 2020 361
Autor:
Tuan Xu, Md Kabir, Srilatha Sakamuru, Pranav Shah, Elias C. Padilha, Deborah K. Ngan, Menghang Xia, Xin Xu, Anton Simeonov, Ruili Huang
Publikováno v:
Journal of Chemical Information and Modeling. 63:846-855
Autor:
Juliano de B Pazini, Anderson D Grützmacher, Enio J Seidel, Afrânio M C Vieira, Aline C Padilha, Giovani G de Brito, Daniel Bernardi, José A F Barrigossi, José F da S Martins
Publikováno v:
Pest Management Science. 79:947-958
Oryzophagus oryzae (Costa Lima) (Coleoptera: Curculionidae) is a major pest of flooded rice paddies throughout South America, and species with very similar life histories are present in many rice-producing regions of the world (collectively rice wate