Zobrazeno 1 - 10
of 2 852
pro vyhledávání: '"A. C. Kelly"'
Autor:
Meijie Tian, Jun S. Wei, Adam Tai-Chi Cheuk, David Milewski, Zhongmei Zhang, Yong Yean Kim, Hsien-Chao Chou, Can Liu, Sherif Badr, Eleanor G. Pope, Abdelrahman Rahmy, Jerry T. Wu, Michael C. Kelly, Xinyu Wen, Javed Khan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Chimeric antigen receptor (CAR) T-cells targeting Fibroblast Growth Factor Receptor 4 (FGFR4), a highly expressed surface tyrosine receptor in rhabdomyosarcoma (RMS), are already in the clinical phase of development, but tumour heterogeneity
Externí odkaz:
https://doaj.org/article/a3964d3bf8e04e298aea51cf07822727
Autor:
Drishti D. Sinha, MD, MPHS, Megan Foeller, MD, Abigail S. Bell, BA, Anthony J. Nixon, Jr., MPH, Darrell Hudson, PhD, MPH, Aimee S. James, PhD, MPH, Amy R. Scheffer, Ana A. Baumann, PhD, Emily Diveley, RN, Ebony B. Carter, MD, MPH, Nandini Raghuraman, MD, MSCI, Indira U. Mysorekar, PhD, Jeannie C. Kelly, MD, MS
Publikováno v:
AJOG Global Reports, Vol 4, Iss 4, Pp 100392- (2024)
Background: The Coronavirus disease 2019 (COVID-19) pandemic led to healthcare system changes aimed at minimizing disease transmission that impacted experiences with obstetric healthcare. Objective: To explore experiences of clinicians providing obst
Externí odkaz:
https://doaj.org/article/86bcee1f900e42beb37e7676c5ed7ed7
Autor:
Jiameng Sun, Yiming Zhang, Joshua A. Adams, Cassandra B. Higgins, Shannon C. Kelly, Hao Zhang, Kevin Y. Cho, Ulysses G. Johnson, Benjamin M. Swarts, Shun-Ichi Wada, Gary J. Patti, Leah P. Shriver, Brian N. Finck, Erik D. Herzog, Brian J. DeBosch
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114865- (2024)
Summary: Organisms integrate circadian and metabolic signals to optimize substrate selection to survive starvation, yet precisely how this occurs is unclear. Here, we show that hepatocyte Period 1 (Per1) is selectively induced during fasting, and mic
Externí odkaz:
https://doaj.org/article/f3f84b6930c6468d8267aafa1547506a
Autor:
S. Rangecroft, C. Clason, R. M. Dextre, I. Richter, C. Kelly, C. Turin, C. V. Grados-Bueno, B. Fuentealba, M. Camacho Hernandez, S. Morera Julca, J. Martin, J. A. Guy
Publikováno v:
Geoscience Communication, Vol 7, Pp 145-150 (2024)
Here we share four key lessons from an interdisciplinary project (Nuestro Rio) that gathered community perspectives on local water quality in the Santa River basin (Peru) utilising a digital technological approach where we collected data via a novel
Externí odkaz:
https://doaj.org/article/b9b3903dd8c04da797af2430bba46b12
Autor:
Subhash Banerjee, MD, Rick A. Weideman, PharmD, David A. Jacob, PharmD, Helene R. DiGregorio, MD, Kevin C. Kelly, PharmD, Avantika Banerjee, MD, Milan Ravishankar, MD, Patrick T. Strickland, MD, Helayna M. Abraham, MD, Nicole E. Minniefield, MD, Bradley R. Grimsley, MD, Jeffrey M. Schussler, MD, Rohit J. Parmar, MD, Robert C. Stoler, MD, Emmanouil S. Brilakis, MD, PhD, Bertis B. Little, PhD
Publikováno v:
JACC: Advances, Vol 4, Iss 1, Pp 101459- (2025)
Background: Estimation of long-term risk for cardiovascular events using the SMART (Secondary Manifestations of Arterial Disease) risk score can be potentially valuable in devising risk mitigation strategies. Objectives: The objective of this study w
Externí odkaz:
https://doaj.org/article/98d8f24f814b487e95984f74f92c4450
Autor:
Joanne Byrne, Lili Gu, Alejandro Garcia-Leon, Colette Marie Gaillard, Gurvin Saini, Dana Alalwan, Julen Tomás-Cortázar, Grace Kenny, Sean Donohue, Bearach Reynolds, Tessa O’Gorman, Alan Landay, Peter Doran, Jannik Stemler, Philipp Koehler, Rebecca Jane Cox, Ole F. Olesen, Jean-Daniel Lelievre, Cathal O’Broin, Stefano Savinelli, Eoin R. Feeney, Jane A. O’Halloran, Aoife Cotter, Mary Horgan, Christine Kelly, Corrina Sadlier, Eoghan de Barra, Oliver A. Cornely, Virginie Gautier, Patrick WG Mallon, All Ireland Infectious Diseases cohort study and VACCELERATE consortium, A. Cotter, E. Muldoon, G. Sheehan, T. McGinty, J. S. Lambert, T. O’Gorman, C. Kelly, K. Leamy, J. Byrne, G. Kenny, K. McCann, R. McCann, C. O’Broin, S. Savinelli, J. O’Halloran, E. Feeney, P. W. G. Mallon, A. Garcia Leon, S. Miles, D. Alalwan, R. Negi, G. Saini, E. Moore, E. de Barra, S. McConkey, K. Hurley, B. Jacob, F. Lyons, M. Horgan, C. Sadlier, T. Bracken, B. Whelan, J Low, O Yousif, B. McNicholas, G. Courtney, C. O’Maoldomhnaigh, P. Gavin, Julia M. Neuhann, Ullrich Bethe, Sarah Heringer, Jon Salmanton-Garcı́a, Lea Tischmann, Arnd Cüppers, Jan Grothe, Antonio J. Carcas, Jesús Frías-Iniesta, Murat Akova, Alejandro Garcia Leon, Patrick Mallon, Riya Negi, Colette Gaillard, Christine Lammens, An Hotterbeekx, Katherine Loens, Surbhi Malhotra-Kumar, Herman Goossens, Samir Kumar-Singh, Franz König, Lusine Yeghiazaryan, Martin Posch
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionA clear immune correlate of protection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has not been defined. We explored antibody, B-cell, and T-cell responses to the third-dose vaccine and relationship to inci
Externí odkaz:
https://doaj.org/article/1469edd2e8884d0ab79ea55f12a635fa
Publikováno v:
South African Journal of Radiology, Vol 28, Iss 1, Pp e1-e5 (2024)
Background: Acute kidney injury (AKI) is common among hospitalised patients and can lead to significant morbidity or mortality if not properly managed. Renal ultrasound (RUS) is often requested in the initial workup of AKI to rule out obstructive uro
Externí odkaz:
https://doaj.org/article/60a61d89087b4006983a78df92643edb
Publikováno v:
IEEE Access, Vol 12, Pp 52215-52226 (2024)
A federated learning-based intrusion detection system (FL-IDS) is introduced to enhance the security of vehicular networks in the context of IoT edge device implementations. The FL-IDS system protects data privacy by using local learning, in which de
Externí odkaz:
https://doaj.org/article/15a7831d69f94f7389867aa52738b308
Autor:
Yiming Zhang, Jiameng Sun, Henry D. Wasserman, Joshua A. Adams, Cassandra B. Higgins, Shannon C. Kelly, Louise Lantier, Brian J. DeBosch
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 5, Pp 801-820 (2024)
Background & Aims: Restoring hepatic and peripheral insulin sensitivity is critical to prevent or reverse metabolic syndrome and type 2 diabetes. Glucose homeostasis comprises in part the complex regulation of hepatic glucose production and insulin-m
Externí odkaz:
https://doaj.org/article/c22f4337f0d34c74a26c716f33616718
Autor:
Aya Ushio, Mami Matsuda-Lennikov, Felix Kalle-Youngoue, Akihide Shimizu, Abdalla Abdelmaksoud, Michael C. Kelly, Naozumi Ishimaru, Yousuke Takahama
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114072- (2024)
Summary: Medullary thymic epithelial cells (mTECs) are essential for the establishment of self-tolerance in T cells. Promiscuous gene expression by a subpopulation of mTECs regulated by the nuclear protein Aire contributes to the display of self-geno
Externí odkaz:
https://doaj.org/article/7078fd472f85403aa1d52ace8be585dd