International Health Electives: defining learning outcomes for a unique experience

Autor: M. A. C. Versluis, N. C. Jöbsis, A. D. C. Jaarsma, R. Tuinsma, R. Duvivier

Publikováno v: BMC Medical Education, Vol 23, Iss 1, Pp 1-11 (2023)

Abstract Background An International Health Elective (IHE) can be a unique learning experience for students. However, it has proven difficult to clearly define learning outcomes that capture the complexity of an IHE and are aligned with future profes

Externí odkaz: https://doaj.org/article/d9a7e293735241e790b8d6f65ef2c2ef

FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma

Autor: André N. Vis, Ellen C. Zwarthoff, Theo H. van der Kwast, Wim J. Kirkels, Adriaan C. Jöbsis, Bas W.G. van Rhijn, Egbert R. Boevé

Publikováno v: Van Rhijn, B W G, Van Der Kwast, T H, Vis, A N, Kirkels, W J, Boevé, E R, Jöbsis, A C & Zwarthoff, E C 2004, ' FGFR3 and P53 Characterize Alternative Genetic Pathways in the Pathogenesis of Urothelial Cell Carcinoma ', Cancer Research, vol. 64, no. 6, pp. 1911-1914 . https://doi.org/10.1158/0008-5472.CAN-03-2421
Cancer Research, 64(6), 1911-1914. American Association for Cancer Research Inc.
Cancer Research, 64, 1911-1914. American Association for Cancer Research Inc.

Fibroblast growth factor receptor 3 (FGFR3) and P53 mutations are frequently observed in bladder cancer. We here describe the distribution of FGFR3 mutations and P53 overexpression in 260 primary urothelial cell carcinomas. FGFR3 mutations were obser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49170a3870d21e9180d9fb275e60503b
https://pure.eur.nl/en/publications/8e016aa0-8f35-490e-a0d2-32febb0fd7d5

Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications

Autor: Alexandre R. Zlotta, Tahlita C.M. Zuiverloon, Liyang Liu, Mireia Musquera, Adriaan C. Jöbsis, Michael A.S. Jewett, Geert J.L.H. van Leenders, Egbert R. Boevé, Bharati Bapat, Ellen C. Zwarthoff, Theo van der Kwast, André N. Vis, Bas W.G. van Rhijn, Wim J. Kirkels

Publikováno v: Modern Pathology, 28(5), 695-705. Nature Publishing Group
van Rhijn, B W G, Musquera, M, Liu, L, Vis, A N, Zuiverloon, T C M, van Leenders, G J L H, Kirkels, W J, Zwarthoff, E C, Boevé, E R, Jöbsis, A C, Bapat, B, Jewett, M A S, Zlotta, A R & van der Kwast, T H 2015, ' Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications ', Modern Pathology, vol. 28, no. 5, pp. 695-705 . https://doi.org/10.1038/modpathol.2014.154

Currently, the use of two classification systems for bladder cancer grade is advocated in clinical guidelines because the WHO2004 classification has not been sufficiently validated with biological markers and follow-up. The slides of 325 primary non-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b7159cf2bc0d348226bb397dda0628
https://pure.eur.nl/en/publications/6e7437d8-5600-40f2-b588-e18d91cc85e5

Thyroid morphology in lethal non-thyroidal illness: a post-mortem study

Autor: A. C. Jöbsis, F. E. De Jongh, J. W. F. Elte

Publikováno v: European Journal of Endocrinology. :221-226

OBJECTIVE: Non-thyroidal illness (NTI) is associated with alterations in thyroid hormone metabolism. Whether morphological changes of the thyroid gland accompany NTI is unknown. The aim of the present study was to describe thyroid morphology in patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f65d7dd01fa8916d562fb1537736710
https://doi.org/10.1530/eje.0.1440221

Frequent FGFR3 mutations in urothelial papilloma

Autor: Bas W G, van Rhijn, Rodolfo, Montironi, Ellen C, Zwarthoff, Adriaan C, Jöbsis, Theo H, van der Kwast

Publikováno v: The Journal of pathology. 198(2)

Activating point mutations in the FGFR3 gene occur frequently in low-grade and low-stage bladder carcinomas, whereas they are rare in high-grade carcinomas. This study investigates the incidence of FGFR3 mutations in 12 urothelial papillomas and 79 p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c76284d1845043ee73e62d2d1b0ea2ee
https://pubmed.ncbi.nlm.nih.gov/12237885